GB2156343B - 13,14,19,19,20,20-hexadehydro derivatives of carboprostacyclins and process for their preparation - Google Patents

13,14,19,19,20,20-hexadehydro derivatives of carboprostacyclins and process for their preparation

Info

Publication number
GB2156343B
GB2156343B GB08407794A GB8407794A GB2156343B GB 2156343 B GB2156343 B GB 2156343B GB 08407794 A GB08407794 A GB 08407794A GB 8407794 A GB8407794 A GB 8407794A GB 2156343 B GB2156343 B GB 2156343B
Authority
GB
United Kingdom
Prior art keywords
carboprostacyclins
hexadehydro
derivatives
preparation
hexadehydro derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08407794A
Other versions
GB8407794D0 (en
GB2156343A (en
Inventor
Nicola Mongelli
Roberto Ceserani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ERBO SpA FARMITALIA CARLO
Pfizer Italia SRL
Original Assignee
ERBO SpA FARMITALIA CARLO
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ERBO SpA FARMITALIA CARLO, Farmitalia Carlo Erba SRL filed Critical ERBO SpA FARMITALIA CARLO
Priority to GB08407794A priority Critical patent/GB2156343B/en
Publication of GB8407794D0 publication Critical patent/GB8407794D0/en
Priority to IT19765/85A priority patent/IT1183477B/en
Priority to DE19853507940 priority patent/DE3507940A1/en
Priority to JP60055777A priority patent/JPS60209546A/en
Priority to BE0/214703A priority patent/BE902015A/en
Publication of GB2156343A publication Critical patent/GB2156343A/en
Application granted granted Critical
Publication of GB2156343B publication Critical patent/GB2156343B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
GB08407794A 1984-03-26 1984-03-26 13,14,19,19,20,20-hexadehydro derivatives of carboprostacyclins and process for their preparation Expired GB2156343B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB08407794A GB2156343B (en) 1984-03-26 1984-03-26 13,14,19,19,20,20-hexadehydro derivatives of carboprostacyclins and process for their preparation
IT19765/85A IT1183477B (en) 1984-03-26 1985-03-05 13,14,19,19,20,20-HEXADERIDE CARBOSTACYCLINE DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
DE19853507940 DE3507940A1 (en) 1984-03-26 1985-03-06 13,14,19,19,20,20-HEXADEHYDRO DERIVATIVES OF CARBOPROSTACYCLINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AND ANIMAL MEDICAL PREPARATIONS CONTAINING THEM
JP60055777A JPS60209546A (en) 1984-03-26 1985-03-22 13,14,19,19,20,20-hexadehydro derivatives of carboprostacyclines and manufacture
BE0/214703A BE902015A (en) 1984-03-26 1985-03-25 NEWS 13,14,19,19,20-HEXADEHYDRO-CARBOPROSTACYCLINES AND METHOD OF PREPARATION.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08407794A GB2156343B (en) 1984-03-26 1984-03-26 13,14,19,19,20,20-hexadehydro derivatives of carboprostacyclins and process for their preparation

Publications (3)

Publication Number Publication Date
GB8407794D0 GB8407794D0 (en) 1984-05-02
GB2156343A GB2156343A (en) 1985-10-09
GB2156343B true GB2156343B (en) 1988-01-13

Family

ID=10558691

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08407794A Expired GB2156343B (en) 1984-03-26 1984-03-26 13,14,19,19,20,20-hexadehydro derivatives of carboprostacyclins and process for their preparation

Country Status (5)

Country Link
JP (1) JPS60209546A (en)
BE (1) BE902015A (en)
DE (1) DE3507940A1 (en)
GB (1) GB2156343B (en)
IT (1) IT1183477B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2845770A1 (en) * 1978-10-19 1980-04-30 Schering Ag NEW PROSTACYCLINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
GB8407794D0 (en) 1984-05-02
IT8519765A0 (en) 1985-03-05
GB2156343A (en) 1985-10-09
DE3507940A1 (en) 1985-09-26
IT1183477B (en) 1987-10-22
BE902015A (en) 1985-07-16
JPS60209546A (en) 1985-10-22

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee