GB2155204A - Method and apparatus for Korsakovian dilution - Google Patents

Abstract

An apparatus for producing very dilute solutions in which the walls of a vessel are coated with a master tincture. A measured volume of distilled water is introduced into the vessel. After agitation the vessel is emptied and the process of filling with water, agitation and emptying is repeated until the required dilution is attained. A display indicates the number of cycles carried out. <IMAGE>

Description

SPECIFICATION Method and apparatus for Korsakovian dilution The present invention relates to a method and an apparatus making it possible to carry out automatically and in an industrial sequence dilutions of the type done particularly for producing homeopathic medicines.

The method and apparatus relates more particularly but not exclusively to the operation known under the name of "Korsakovian dilution The manufacture of a homeopathic medicine by this process requires impregnating the inner wall of a bottle with a master tincture, filling the bottle with a premeasured amount of distilled water, then agitating the water by repeated standard shakings, and emptying the bottle. Since traces of the solution to be diluted still adhere to the inner wall of the bottle, it is filled anew with a new premeasured amount of distilled water, and subjected to a new agitation operation, and so on.

Traditionally, the dilution operations were performed manually. Besides the fact that this involves a considerable expenditure of manual work, there is a danger of error in counting the successive dilution cyles, especially if there are many cycles.

The primary object of the present invention is to provide a method and an apparatus capable of carrying out the successive Korsakovian dilution operations of the type of those observed in the production of homeopathic medicines whilst avoiding the above disadvantages.

The present invention provides a method and an apparatus for a Korsakovian dilution intended to process at least one bottle for refilling it, agitating its contents and emptying the latter before starting another similar cycle.

The apparatus of the present invention for processing at least one bottle by impregnating the inner wall of said at least one bottle with a tincture and repeatedly filling said at least one bottle with a predetermined amount of fluid comprises automatic control means for automatically carrying out the above process and repetition thereof.

According to one feature of the present invention the apparatus is characterised in that it includes two distinct sub-assemblies.

The first sub-assembly is a mechanical apparatus where the bottle is mounted on the shaking clamp of an agitator. The bottle is connected by a first pipe to a feed station filled with distilled water. The bottle is connected by a second pipe with a draining station.

The second sub-assembly is a control apparatus including the electronic components which automatically insure control of the dosing, the starting of each operation and the display of the number of dilutions made. A first counter serves to display the number of dilutions desired. A second counter indicates at any moment the number of dilutions made.

According to another feature of the present invention, the mechanical unit has two similar stations where two identical operations take place completely independently.

According to still another feature of the present invention, the dosing is ensured by piston syringes, each of which has a selectively adjustable filling stroke.

According to yet another feature of the present invention, a three-way cock is provided at each dosing station for the intake and delivery 6f the liquid.

The attached drawings illustrate an example of an apparatus according to the present invention and are provided as a non-limiting example to facilitate understanding of the many objects, features, and advantages of the present invention.

Figure 1 is an overall view diagrammatically illustrating the principle of operation of a dilution apparatus according to the present invention with two operating stations; Figure 2 shows the corresponding mechanical unit where two bottles are processed at the same time; Figure 3 shows details of the "water trap" according to the present invention provided for verifying that the corresponding bottle is emptied; Figure 4 is a cutaway view and illustrates the principle of operation of each dosing station according to the present invention.

Figure 5 is a front elevational view showing the whole of the control box of the control unit.

Figure 6 is a side elevational view of portions of the control box of Figure 5; and Figure 7 is a front view of a possible embodiment of a control console through which an operator operates and controls the apparatus of the present invention.

Referring now to the drawings, and more partic ularlyto Figure 1, a mechanical apparatus 26 according to the invention is provided for processing two bottles 1 and 2 independently but with the same cycle. Each of these bottles contains a solution of a medicinal master tincture which is proposed to reduce in concentration by the Korsakov method until homeopathic dilutions are obtained.

As best shown in Figure 2, the mechanical apparatus 26 includes two agitators 3 and 4, each of which has a clamp 5. Each clamp 5 is placed at the end of an arm 6 which can swing around a fixed pin 7. The end of the arm 6 beyond the fixed pin 7 is pivotally mounted to one end of a rod 8 driven by an eccentric 9. A motor, not represented, drives the rotation of the eccentric 9 during the agitation cycle. Thus each clamp 5 is subjected to a shaking motion transmitted to the bottle 1 and 2 which it contains.

The mechanical apparatus 26 illustrated in Figures 1 and 2 moreover includes two feed stations 10 and 11. These two stations are identical to one another. The station 10 has been illustrated in more detail in Figure 4.

The station 10 includes two vertical syringes 12 and 13, the fixed cylinders 12a and 13a, respectively, of which are placed side by side. The pistons 12b and 13b, respectively, of each syringe 12 and 13 are interconnected with a base plate 15.

The base plate 15 is a distance 16 from a drive carriage 17 which is fixed, but adjustable by means of a knurled nut 18. The carriage 17 causes the emptying of the cylinders 12a and 13a by an alternating vertical movement in the direction of the arrow 19.

For this purpose, the face of the base plate 15 opposite the pistons 12b and 13b has a roller 20. An eccentric 21 driven by a motor, not illustrated, rotates thereunder and engages the roller 20. The useful stroke of the pistons 12b and 13b, respectively, for the two syringes 12 and 13 can be adjusted, as desired, by rotation of the knurled nut 18 to adjust the distance 16.

The cylinders 12a and 13a are surmounted by a valve box 22, the intakes 23 of which are connected to a distilled water reservoir 24, shown only in Figure 1, surmounting the assembly. The delivery openings of the valve box 22 are each connected by a flexible line 25 to the detachable bottle fitting of the corresponding bottle 1 or 2 into which it empties. The detachable bottle fitting is not illustrated in the drawing but is provided generally at 14, as shown in Figures 1 and 2.

Thus the syringes 12 and 13 draw in an amount of distilled water which can be proportioned with the aid of the knurled nut 18, and then they deliver it into the bottles, 1 and 2, respectively.

The eccentrics 21 are driven at the two feed stations 10 and 11. Thus, the syringe 12 of the feed station 10 draws in a proportioned amount of distilled water, independently of the movement of the syringe 12 of the feed station 11.

The mechanical apparatus 26 also has an intake and drainage station 27, as shown in Figures 1 and 2. The intake and drainage station 27, as shown in Figure 1, consists of a vacuum pump 28 which, by way of a condenser 29, provides continuous suction in a line 30. The line 30 is divided by forking into two lines 31 and 32, each provided with an opening or closing electromagnetic valve 33 and 34, respectively. The line 31 is connected, by way of a control cell 35 or water trap, to a line 36 which goes through the bottle fitting 14 of the bottle 1 to go into the bottle 1.

Similarly, the line 32 is connected by a control cell 37 or water trap to an intake line 38 into the interior of the bottle 2.

Each of the intake lines 36 and 38 goes into the bottom of the corresponding bottle 1 or 2, in such a manner as to be able to empty the bottles as completely as possible.

The control cells 35 and 37 are identical, and only one of these, the cell 35, has been illustrated in detail in Figure 3. The cell 35 consists of a reservoir 39 provided at its base with an opening or closing electromagnetic valve 40. The tight lid 41 of the reservoir 39 is crossed by the corresponding ends of the lines 31 and 36. The line 31 maintains a reduced pressure inside the reservoir 39.

The reduced pressure has the effect of intake of the liquid 42 coming from the bottle 1. As long as the electromagnetic draining valve 40 remains closed, the liquid 42 accumulates in the reservoir 39, and a little ball 43 floats on its surface. A radiation transmitting cell 44 and a receiving cell 45 are built in face to face in the wall of the reservoir 39.

If the level of the liquid 42 puts the floating ball 43 between the transmitter 44 and the receiver 45, the radiation transmitted by the radiation transmitting cell 44 becomes interrupted. The receiver 45 then detects the presence of the ball 43 and actuates the opening of the draining valve 40. When the ball 43 drops to the bottom of the reservoir 39, it is certain that the bottle 1 has been completely emptied, and the receiver 45 simultaneously actuates the closing of the two electromagnetic valves 33 and 40.

The control cell 37 operates in the same manner as the control cell 35.

By this arrangement, a single vacuum pump 28 is used to selectively empty one or another of the two bottles 1 and 2.

The control apparatus 70 according to the present invention is illustrated in Figures 5 to 7. The control apparatus 70 ensures the operation in sequence of the programmes on the two stations of the mechanical apparatus 26.

The control apparatus 70, as shown in Figure 5, includes a terminal unit 46, a supply transformer 47, memory relays 48, 49 and 50, time-lag relays 51, and two counters 52 and 53 each relating to one of the feed stations 10 and 11, respectively, for counting their cycles.

The control apparatus 70 is further provided with a control console 54, best shown in Figure 7. The control console 54 includes a general start-stop switch 55, a pilot iamp 56 for starting authorisation, a pilot lamp 57 signalling the existence of voltage, and two control units 58 and 59 corresponding to each of the two feed stations, 10 and 11, respectively.

Each of the control units 58 and 59 includes digital indicators 60 which display at each moment the number of dilutions carried out and the desired number of dilutions and indicators 61 for monitoring the volume, and for signalling whether the dosing is good or if it is defective, or if some other defect appears. Each of the control units 58 and 59 includes a display 62 for the automatic operation, that is, automatic start-stop, and a display 63 for manual control, that is, one grouping the buttons and indicators which makes it possible to actuate, one by one, the successive operations of starting, dosing, agitating, intake, draining, etc.

The operation of the present invention is as follows: The operator initiates the operation of the apparatus by means of the start-stop switch 55. With the aid of the displays 62 and 63, the operator chooses an automatic operating sequence, or one with manual control, for the dilution operations.

When the bottle 1 is full of the diluted master tincture, the valve 33 is opened, which causes the intake of the liquid. Once the bottle I is emptied, the floating ball 43 causes the draining valve 40 to open, while the valve 33 is closed. Thus "the vacuum is broken".

The syringes of the dosing station 10 then send to the bottle 1 a proportioned quantity of distilled water, which makes the dilution, while the agitator 3 agitates the bottle 1. At the end of this operation the valve 33 is opened anew, which empties the bottle into the water trap 35. Once the emptying operation is complete, the valve 40 is opened anew. The above operations are therefore repeated for a preselected number of cycles.

The number of dilution cycles is automatically displayed on the instrument panel 54.

As stated previously, the operating cycles are staggered on the two feed statidns 10 and 11, which makes it possible to use only a single vacuum pump 29 connected alternately to the bottle 1, then to the bottle 2.

It will be appreciated by those skilled in the art that many modifications and variations are possible to the method and apparatus described above within the scope of the present invention. Such modifications and variations are within the intended scope of the claims appended hereto.

Claims (11)

1. A Korsakovian dilution apparatus for processing at least one bottle by impregnating the inner wall of said at least one bottle with a tincture and repeatedly filling said at least one bottle with a predetermined amount of fluid wherein automatic control means is provided for automatically carrying out the above process and repetition thereof.

2. A Korsakovian dilution apparatus according to Claim 1 for processing at least one bottle by impregnating the inner wall of said at least one bottle with a tincture and repeatedly filling said at least one bottle with a predetermined amount of fluid, agitating said at least one bottle to dissolve a portion of said tincture into said fluid to produce a solution, and emptying said solution from said bottle for a predetermined number of cycles, said Korsakovian dilution apparatus comprising:: bottle clamping means for securing said at least one bottle; fluid supply means for selectively supplying said at least one bottle with said predetermined amount of fluid; shaking means selectively imparting a shaking motion to said bottle clamping means such that a portion of said tincture dissolves in said fluid to produce said solution; solution intake means selectively operable to draw said solution from said at least one bottle; automatic control means sequentially controlling said fluid supply means, said shaking means, and said intake means to repeatedly produce said solution from said predetermined amount of said fluid; and automatic counting means counting the number of cycles of operation controlled by said automatic control means.

3. A Korsakovian dilution apparatus according to Claim 2, wherein said fluid is distilled water.

4. A Korsakovian dilution apparatus according to Claim 2 or Claim 3, wherein said fluid supply means comprises at least one syringe having a cylinder, a piston, and stroke adjusting means such that the stroke of said syringe is adjustable to provide said predetermined amount of fluid.

5. A Korsakovian dilution apparatus according to Claim 4, wherein said fluid supply means further comprises; at least one syringe having a cylinder, and a piston movably inserted into said cylinder, said cylinder and said piston each having a free end; frame means interconnected with one of said free ends; plate means interconnected with the other of said free ends opposite said one of said free ends; and rotary eccentric means interposed said plate means and said frame means, said rotary eccentric means reciprocating said plate means relative to said frame means and, thereby, reciprocating said piston relative to said cylinder to inject a preselected quantity of fluid into said at least one bottle.

6. A Korsakovian dilution apparatus according to Claim 5, further comprising adjustment means interposed said other free end and said plate means such as to permit adjustment of said preselected quantity of fluid to said predetermined amount of fluid.

7. A Korsakovian dilution apparatus according to any one of Claims 2 to 6, wherein said fluid supply means further comprises two syringes selectively operable simultaneously to inject said predetermined amount of fluid into said at least one bottle.

8. A Korsakovian dilution apparatus according to any one of Claims 2 to 7, wherein said shaking means comprises an arm interconnected with said bottle clamping means and eccentric drive means pivotally driving said arm to oscillate said bottle clamping means.

9. A Korsakovian dilution apparatus according to any one of the Claims 2 to 8, wherein said solution intake means further comprises: water trap means having a reservoir; a first line extending from said at least one bottle to said reservoir; vacuum pump means having a vacuum port and being selectively operable to create a vacuum pressure at said vacuum port; and a second line extending from said vacuum port to said reservoir to create a vacuum therein such that said vacuum in said reservoir draws said fluid from said at least one bottle into said resrvoir.

10. A Korsakovian dilution apparatus according to Claim 9, wherein said water trap means further comprises first selectively operable valve means at the lower end of said reservoir selectively operable to permit drainage of said solution from said reservoir.

11. A Korsakovian dilution apparatus according to Claim 10, wherein said water trap means further comprises solution level detection means responsive to the level of solution in said reservoir such that when said level of solution reaches a predetermined level indicative of the draining of a predetermined amount of solution from said at least one bottle, said solution level detection means opens said first selectively operable valve means.

11. A Korsakovian dilution apparatus according to Claim 10, wherein said water trap means further comprises solution level detection means responsive to the level of solution in said reservoir such that when said level of solution reaches a predetermined level indicative of the draining of a predetermined amount of solution from said at least one bottle, said solution level detection means opens said first selectively operable valve means.

12. A Korsakovian dilution apparatus according to Claim 11, wherein said solution level detection means further comprises; radiation transmitting means disposed adjacent said reservoir; radiation receiving means disposed adjacent said reservoir and on the opposite side thereof from said radiation transmitting means such that said radiation receiving means detects radiation from said radiation transmitting means which has traversed said reservoir at said predetermined level; and radiation blocking means in said reservoir, said radiation blocking means being comprised of a material having a specific gravity less than said solution such that said radiation blocking means floats in said solution, said radiation blocking means thereby blocking said radiation receiving means from receiving radiation from said radiation transmitting means when said solution reaches said predetermined level.

13. A Korsakovian dilution apparatus according to any one of Claims 10 to 12, further comprising valve closing means selectively operable to close said first selectively operable valve means after said reservoir has been drained of said solution.

14. A Korsakovian dilution apparatus according to any one of Claims 9 to 13, wherein said vacuum pump means comprises: a vacuum pump; and a second selectively operable valve means interposed said vacuum pump and said second line such as to selectively create a vacuum in said reservoir.

15. A Korsakovian dilution apparatus according to any one of Claims 2 to 14, wherein two of said bottles are used, each being impregnated with tincture, said Korsakovian dilution apparatus further comprising: two of said bottle clamping means for independently securing said bottles; two of said fluid supply means for independently supplying said bottles with said fluid; two of said shaking means for shaking said bottle clamping means; and two of said solution intake means for selectively draining solution from said two bottles, said automatic control means sequentially controlling each of said fluid supply means, shaking means, and intake means to repeatedly produce said solution from fluid and said tincture, said automatic control means alternatively supplying fluid to said bottles such that said two bottles supply said solution in an alternating manner.

16. A Korsakovian dilution apparatus according to Claim 15, wherein said two solution intake means comprise: two water trap means each having a reservoir; two first lines each interconnecting one of said reservoirs with one of said bottles; a vacuum pump means having a vacuum port and being selectively operable to create a vacuum pressure at said vacuum port; two second lines each interconnecting said vacuum port with one of said reservoirs; and two second selectively operable valve means each interposed said vacuum port and one of said second lines.

17. A method of Korsakovian dilution comprising the steps of: impregnating two bottles with tincture; alternatingly filling said two bottles with distilled water; shaking each of said two bottles to dissolve a portion of said tincture into said distilled water to produce a solution; and alternatingly drawing said solution from said two bottles using a common vacuum pump means.

18. A method according to Claim 17, further comprising the step of automatically controlling said alternating filling and drawing steps.

19. A method according to Claim 17 or Claim 18, further comprising the step of automatically counting the number of repetitions of said alternatingly drawing step.

20. A Korsakovian dilution apparatus constructed, arranged and adapted to operate substantially as hereinbefore described with reference to, and as illustrated by, the accompanying drawings.

21. A method of Korsakovian dilution substantially as hereinbefore described with reference to, and as illustrated by, the accompanying drawings.

Amendments to the claims have been filed, and have the following effect: (a) Claims 11 and 17, 18, 19 & 21 above have been deleted or textually amended.

(b) New or textually amended claims have been filed as follows: (c) Claim 20 above have been re-numbered as 17 and their appendancies corrected.