GB2148713B - Pharmaceutical composition and food product comprising higher fatty acids - Google Patents

Pharmaceutical composition and food product comprising higher fatty acids

Info

Publication number
GB2148713B
GB2148713B GB08426765A GB8426765A GB2148713B GB 2148713 B GB2148713 B GB 2148713B GB 08426765 A GB08426765 A GB 08426765A GB 8426765 A GB8426765 A GB 8426765A GB 2148713 B GB2148713 B GB 2148713B
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical composition
fatty acids
food product
higher fatty
food
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08426765A
Other versions
GB2148713A (en
GB8426765D0 (en
Inventor
David Rubin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Century Laboratories Inc
Original Assignee
Century Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/545,349 external-priority patent/US4526902A/en
Application filed by Century Laboratories Inc filed Critical Century Laboratories Inc
Publication of GB8426765D0 publication Critical patent/GB8426765D0/en
Publication of GB2148713A publication Critical patent/GB2148713A/en
Application granted granted Critical
Publication of GB2148713B publication Critical patent/GB2148713B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
    • C11C1/025—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by saponification and release of fatty acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
    • A23D7/0056—Spread compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/005—Splitting up mixtures of fatty acids into their constituents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Edible Oils And Fats (AREA)
GB08426765A 1983-10-24 1984-10-23 Pharmaceutical composition and food product comprising higher fatty acids Expired GB2148713B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54535083A 1983-10-24 1983-10-24
US06/545,349 US4526902A (en) 1983-10-24 1983-10-24 Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions

Publications (3)

Publication Number Publication Date
GB8426765D0 GB8426765D0 (en) 1984-11-28
GB2148713A GB2148713A (en) 1985-06-05
GB2148713B true GB2148713B (en) 1987-04-23

Family

ID=27067902

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08426765A Expired GB2148713B (en) 1983-10-24 1984-10-23 Pharmaceutical composition and food product comprising higher fatty acids

Country Status (7)

Country Link
CA (1) CA1239587A (en)
CH (1) CH661209A5 (en)
DE (1) DE3438630A1 (en)
FR (1) FR2553662B1 (en)
GB (1) GB2148713B (en)
IT (1) IT1178170B (en)
SE (1) SE462701B (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8431560B1 (en) 2009-02-10 2013-04-30 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US8551521B2 (en) 2009-04-29 2013-10-08 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8563608B2 (en) 2009-04-29 2013-10-22 Amarin Pharmaceuticals Ireland Limited Methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US8669245B2 (en) 2009-06-15 2014-03-11 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy

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GB8507058D0 (en) * 1985-03-19 1985-04-24 Efamol Ltd Pharmaceutical & dietary compositions
US4792418A (en) * 1985-08-14 1988-12-20 Century Laboratories, Inc. Method of extraction and purification of polyunsaturated fatty acids from natural sources
GB8601915D0 (en) * 1986-01-27 1986-03-05 Efamol Ltd Pharmaceutical compositions
DE3603000A1 (en) * 1986-01-31 1987-08-06 Milupa Ag NEW FATTY MIXTURE OF POLYENIC ACID AND THEIR USE IN THE PRODUCTION OF INFANT FOODS
DE3615710A1 (en) * 1986-05-09 1987-11-26 Hoechst Ag PREPARATIONS FOR THE SYNTHESIS OF PROSTAGLANDINES AND HYDROXY FATTY ACIDS IN BIOLOGICAL SYSTEMS
HU204199B (en) * 1987-03-18 1991-12-30 Caola Kozmetikai Process for producing pharmaceutical compositions containing unsaturated fatty acids and selenium as active components
GB8715914D0 (en) * 1987-07-07 1987-08-12 Efamol Ltd Treatment of cerabral disorders
US4843095A (en) * 1987-08-07 1989-06-27 Century Laboratories, Inc. Free fatty acids for treatment or propyhlaxis of rheumatoid arthritis arthritis
FR2623692B1 (en) * 1987-11-30 1991-05-03 Vernin Jean Gilles NEW DIETETIC OIL
HU210122B (en) * 1988-03-23 1995-02-28 Biorex Kutato Fejlesztoe Kft Process for production of composition against thromboembolytic conditions of circulating system and heart
GB8813766D0 (en) * 1988-06-10 1988-07-13 Efamol Holdings Essential fatty acid compositions
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
IE63225B1 (en) * 1988-09-13 1995-04-05 Efamol Holdings Use of fatty acids in the treatment of myalgic encephalomyelitis
DK162621C (en) * 1989-04-27 1992-04-13 Jon Katborg FOOD FAT PRODUCT AND PROCEDURE FOR PRODUCING THE SAME
DE3924607A1 (en) * 1989-07-21 1991-01-24 Singer Peter Dr Sc Med Diet food contg. omega-3-fatty acid, omega-6-fatty acid - with sodium ions and potassium ions, reducing risk of heart and circulation disease
DE19503993A1 (en) * 1995-02-08 1996-08-14 Johann Friedrich Dr Med Desaga Enteral product contg n-3-fatty acid or deriv and medium chain length tri:glyceride
EP0831805A1 (en) * 1995-06-07 1998-04-01 Martek Biosciences Corporation Methods for controlling highly unsaturated fatty acid content in various tissues
KR100657642B1 (en) 1996-10-11 2006-12-19 스카리스타 리미티드 Oil comprising eicosapentaenoic acid and/or stearidonic acid
DE19903095C2 (en) * 1999-01-27 2003-05-22 Nutrinova Gmbh Obtaining gamma-linolenic acid from protozoa of the genus Colpidium
GB9901809D0 (en) 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
EP2295529B2 (en) 2002-07-11 2022-05-18 Basf As Use of a volatile environmental pollutants-decreasing working fluid for decreasing the amount of pollutants in a fat for alimentary or cosmetic use
SE0202188D0 (en) 2002-07-11 2002-07-11 Pronova Biocare As A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product
US6846942B2 (en) 2003-05-20 2005-01-25 David Rubin Method for preparing pure EPA and pure DHA
ITMI20040069A1 (en) 2004-01-21 2004-04-21 Tiberio Bruzzese USE OF HIGH CONCENTRATION N-3 FATTY ACID COMPOSITIONS FOR THE TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM
ES2281270B1 (en) 2005-11-30 2008-07-01 La Morella Nuts, S.A. FUNCTIONAL FOOD WITH POSITIVE EFFECTS IN THE PREVENTION OF CARDIOVASCULAR DISEASES.
EP3578177A1 (en) 2008-09-02 2019-12-11 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same
WO2011018096A1 (en) * 2009-08-10 2011-02-17 K.D. Pharma Bexbach Gmbh Phytanic acid fractionation process, fatty acid products and use thereof
CA2775339C (en) 2009-09-23 2017-03-28 Amarin Corporation Plc Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
NZ744990A (en) 2010-11-29 2019-10-25 Amarin Pharmaceuticals Ie Ltd Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
EP2775837A4 (en) 2011-11-07 2015-10-28 Amarin Pharmaceuticals Ie Ltd Methods of treating hypertriglyceridemia
EP2800469B1 (en) 2012-01-06 2021-08-25 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering levels of high-sensitivity (hs-crp) in a subject
EP4342546A3 (en) 2012-06-29 2024-05-22 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
US20150265566A1 (en) 2012-11-06 2015-09-24 Amarin Pharmaceuticals Ireland Limited Compositions and Methods for Lowering Triglycerides without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
WO2015195662A1 (en) 2014-06-16 2015-12-23 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
TW201900160A (en) 2017-05-19 2019-01-01 愛爾蘭商艾瑪琳製藥愛爾蘭有限公司 Compositions and Methods for Lowering Triglycerides in a Subject Having Reduced Kidney Function
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
FI4056176T3 (en) 2018-09-24 2024-05-30 Amarin Pharmaceuticals Ie Ltd Methods of reducing the risk of cardiovascular events in a subject
AU2022263358A1 (en) 2021-04-21 2023-11-30 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure

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GB1476624A (en) * 1973-05-30 1977-06-16 Cepbepe Tranquiliser medicaments
GB1604554A (en) * 1978-05-26 1981-12-09 Dyerberg J Pharmaceutical and food formulations
AU527784B2 (en) * 1978-05-26 1983-03-24 Bang, Hans Olaf Dr. Treatment of thromboembolic conditions withall-z)-5, 8, 11, 14, 17-eicosapentaenoic acid
GB2033745B (en) * 1978-05-26 1983-08-17 Wellcome Found Fatty acid and derivatives thereof for use in treatment or prophylaxis of thromboembolic conditions
DE3152174A1 (en) * 1980-06-27 1982-08-12 Nippon Oils & Fats Co Ltd THROMBOSIS-PROPHYLATIC AND CURING AGENT
US4377526A (en) * 1981-05-15 1983-03-22 Nippon Suisan Kaisha, Ltd. Method of purifying eicosapentaenoic acid and its esters
GB8302708D0 (en) * 1983-02-01 1983-03-02 Efamol Ltd Pharmaceutical and dietary composition
FR2548021B1 (en) * 1983-06-29 1986-02-28 Dick P R PROLONGED AND CONTINUOUS DERMAL PHARMACEUTICAL COMPOSITIONS BASED ON ESSENTIAL FATTY ACIDS
GB8319073D0 (en) * 1983-07-14 1983-08-17 Efamol Ltd Fatty acid compositions

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8431560B1 (en) 2009-02-10 2013-04-30 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US8440650B1 (en) 2009-02-10 2013-05-14 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US8518929B2 (en) 2009-02-10 2013-08-27 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US8524698B2 (en) 2009-02-10 2013-09-03 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US8546372B2 (en) 2009-02-10 2013-10-01 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US9056088B2 (en) 2009-04-29 2015-06-16 Amarin Pharmaceuticals Ireland Limited Pharmaceutical compositions comprising fatty acids
US8709475B2 (en) 2009-04-29 2014-04-29 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8617594B2 (en) 2009-04-29 2013-12-31 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8618166B2 (en) 2009-04-29 2013-12-31 Amarin Pharmaceuticals Ireland Limited Methods of treating mixed dyslipidemia
US8623406B2 (en) 2009-04-29 2014-01-07 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8642077B2 (en) 2009-04-29 2014-02-04 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8663662B2 (en) 2009-04-29 2014-03-04 Amarin Pharma, Inc. Stable pharmaceutical composition and methods of using same
US9585856B2 (en) 2009-04-29 2017-03-07 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8680144B2 (en) 2009-04-29 2014-03-25 Amarin Pharmaceuticals Ireland Limited Methods of treating mixed dyslipidemia
US8691871B2 (en) 2009-04-29 2014-04-08 Amarin Pharmaceuticals Ireland Limited Methods of treating mixed dyslipidemia
US8703185B2 (en) 2009-04-29 2014-04-22 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8563608B2 (en) 2009-04-29 2013-10-22 Amarin Pharmaceuticals Ireland Limited Methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US9138415B2 (en) 2009-04-29 2015-09-22 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8551521B2 (en) 2009-04-29 2013-10-08 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US9060983B2 (en) 2009-04-29 2015-06-23 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US9060982B2 (en) 2009-04-29 2015-06-23 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US9072715B2 (en) 2009-04-29 2015-07-07 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8710041B2 (en) 2009-06-15 2014-04-29 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy
US8669245B2 (en) 2009-06-15 2014-03-11 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy

Also Published As

Publication number Publication date
IT1178170B (en) 1987-09-09
IT8449063A1 (en) 1986-04-24
SE8405308L (en) 1985-04-25
FR2553662B1 (en) 1989-06-09
SE462701B (en) 1990-08-20
FR2553662A1 (en) 1985-04-26
CA1239587A (en) 1988-07-26
GB2148713A (en) 1985-06-05
IT8449063A0 (en) 1984-10-24
DE3438630A1 (en) 1985-05-02
SE8405308D0 (en) 1984-10-24
GB8426765D0 (en) 1984-11-28
CH661209A5 (en) 1987-07-15

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19931023