GB2146351A - Monoclonal antibody - Google Patents

Monoclonal antibody

Info

Publication number
GB2146351A
GB2146351A GB08423719A GB8423719A GB2146351A GB 2146351 A GB2146351 A GB 2146351A GB 08423719 A GB08423719 A GB 08423719A GB 8423719 A GB8423719 A GB 8423719A GB 2146351 A GB2146351 A GB 2146351A
Authority
GB
United Kingdom
Prior art keywords
monoclonal antibody
alpha
sub
type human
human interferon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB08423719A
Other versions
GB8423719D0 (en
GB2146351B (en
Inventor
David Stanley Secher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB8423719D0 publication Critical patent/GB8423719D0/en
Publication of GB2146351A publication Critical patent/GB2146351A/en
Application granted granted Critical
Publication of GB2146351B publication Critical patent/GB2146351B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A monoclonal antibody having a greater binding efficiency to D sub-type human interferon- alpha than to A sub-type human interferon- alpha . A particular monoclonal antibody is designated YOK5/19. A process is described for the preparation of the monoclonal antibody and uses of the monoclonal antibody in immunopurification and immunoassay are described.
GB08423719A 1983-02-04 1984-02-06 Monoclonal antibody Expired GB2146351B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838303165A GB8303165D0 (en) 1983-02-04 1983-02-04 Monoclonal antibody
PCT/GB1984/000031 WO1984003105A1 (en) 1983-02-04 1984-02-06 Monoclonal antibody

Publications (3)

Publication Number Publication Date
GB8423719D0 GB8423719D0 (en) 1984-10-24
GB2146351A true GB2146351A (en) 1985-04-17
GB2146351B GB2146351B (en) 1986-10-22

Family

ID=10537497

Family Applications (2)

Application Number Title Priority Date Filing Date
GB838303165A Pending GB8303165D0 (en) 1983-02-04 1983-02-04 Monoclonal antibody
GB08423719A Expired GB2146351B (en) 1983-02-04 1984-02-06 Monoclonal antibody

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB838303165A Pending GB8303165D0 (en) 1983-02-04 1983-02-04 Monoclonal antibody

Country Status (4)

Country Link
EP (1) EP0134803A1 (en)
JP (1) JPS60500714A (en)
GB (2) GB8303165D0 (en)
WO (1) WO1984003105A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3306060A1 (en) * 1983-02-22 1984-08-23 Boehringer Ingelheim International GmbH, 6507 Ingelheim NEW IMMUNGLOBULIN-PRODUCING HYBRID CELL LINES, THEIR USE AND METHOD FOR THE PRODUCTION THEREOF
FR2560212B1 (en) * 1984-02-24 1989-12-29 Unicet MONOCLONAL ANTIBODIES AGAINST INTERFERON A2 AND HYBRIDOMAS PRODUCING SUCH ANTIBODIES
US6007805A (en) * 1994-03-07 1999-12-28 Imperial College Of Science And Technology Use of interferon subtype alpha-8 (IFN-α8) to treat viral infections of the liver
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
AU2007327995B2 (en) 2006-12-06 2013-10-10 Medimmune, Llc Interferon alpha-induced pharmacodynamic markers
JP5411129B2 (en) 2007-05-03 2014-02-12 メディミューン，エルエルシー Interferon alpha-inducible pharmacodynamic marker
CA2703705A1 (en) 2007-11-05 2009-05-14 Medimmune, Llc Methods of treating scleroderma
KR20110005783A (en) 2008-02-08 2011-01-19 메디뮨 엘엘씨 Disease markers and uses therof
BR112012004781A2 (en) 2009-09-03 2017-02-14 Medimmune Llc diagnosis of interferon type 1
JP2022520417A (en) 2019-02-15 2022-03-30 アストラゼネカ・アクチエボラーグ Type I interferon-mediated disorders

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981002899A1 (en) * 1980-04-11 1981-10-15 D Secher Monoclonal antibody
WO1982001773A1 (en) * 1980-11-07 1982-05-27 Secher David S Assay for interferon
FR2500754A1 (en) * 1981-02-27 1982-09-03 Hoffmann La Roche MONOCLONAL ANTIBODIES

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981002899A1 (en) * 1980-04-11 1981-10-15 D Secher Monoclonal antibody
WO1982001773A1 (en) * 1980-11-07 1982-05-27 Secher David S Assay for interferon
FR2500754A1 (en) * 1981-02-27 1982-09-03 Hoffmann La Roche MONOCLONAL ANTIBODIES

Also Published As

Publication number Publication date
GB8423719D0 (en) 1984-10-24
WO1984003105A1 (en) 1984-08-16
EP0134803A1 (en) 1985-03-27
JPS60500714A (en) 1985-05-16
GB8303165D0 (en) 1983-03-09
GB2146351B (en) 1986-10-22

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee