GB2146351A - Monoclonal antibody - Google Patents
Monoclonal antibodyInfo
- Publication number
- GB2146351A GB2146351A GB08423719A GB8423719A GB2146351A GB 2146351 A GB2146351 A GB 2146351A GB 08423719 A GB08423719 A GB 08423719A GB 8423719 A GB8423719 A GB 8423719A GB 2146351 A GB2146351 A GB 2146351A
- Authority
- GB
- United Kingdom
- Prior art keywords
- monoclonal antibody
- alpha
- sub
- type human
- human interferon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
A monoclonal antibody having a greater binding efficiency to D sub-type human interferon- alpha than to A sub-type human interferon- alpha . A particular monoclonal antibody is designated YOK5/19. A process is described for the preparation of the monoclonal antibody and uses of the monoclonal antibody in immunopurification and immunoassay are described.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838303165A GB8303165D0 (en) | 1983-02-04 | 1983-02-04 | Monoclonal antibody |
PCT/GB1984/000031 WO1984003105A1 (en) | 1983-02-04 | 1984-02-06 | Monoclonal antibody |
Publications (3)
Publication Number | Publication Date |
---|---|
GB8423719D0 GB8423719D0 (en) | 1984-10-24 |
GB2146351A true GB2146351A (en) | 1985-04-17 |
GB2146351B GB2146351B (en) | 1986-10-22 |
Family
ID=10537497
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB838303165A Pending GB8303165D0 (en) | 1983-02-04 | 1983-02-04 | Monoclonal antibody |
GB08423719A Expired GB2146351B (en) | 1983-02-04 | 1984-02-06 | Monoclonal antibody |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB838303165A Pending GB8303165D0 (en) | 1983-02-04 | 1983-02-04 | Monoclonal antibody |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0134803A1 (en) |
JP (1) | JPS60500714A (en) |
GB (2) | GB8303165D0 (en) |
WO (1) | WO1984003105A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3306060A1 (en) * | 1983-02-22 | 1984-08-23 | Boehringer Ingelheim International GmbH, 6507 Ingelheim | NEW IMMUNGLOBULIN-PRODUCING HYBRID CELL LINES, THEIR USE AND METHOD FOR THE PRODUCTION THEREOF |
FR2560212B1 (en) * | 1984-02-24 | 1989-12-29 | Unicet | MONOCLONAL ANTIBODIES AGAINST INTERFERON A2 AND HYBRIDOMAS PRODUCING SUCH ANTIBODIES |
DE69528751T2 (en) * | 1994-03-07 | 2003-07-10 | Imperial College Of Science, Technology & Medicine | Use of Interferon alpha 8 subtype for the preparation of medicaments for the treatment of viral infections of the liver |
US7087726B2 (en) | 2001-02-22 | 2006-08-08 | Genentech, Inc. | Anti-interferon-α antibodies |
KR20090088932A (en) | 2006-12-06 | 2009-08-20 | 메디뮨 엘엘씨 | Methods of treating systemic lupus erythematosus |
WO2008137835A2 (en) | 2007-05-03 | 2008-11-13 | Medimmune, Llc | Auto-antibody markers of autoimmune disease |
ES2557352T3 (en) | 2007-11-05 | 2016-01-25 | Medimmune, Llc | Methods of treatment of scleroderma |
US20110262928A1 (en) | 2008-02-08 | 2011-10-27 | Medimmune Llc | Disease markers and uses thereof |
KR20120101340A (en) | 2009-09-03 | 2012-09-13 | 메디뮨 엘엘씨 | Type 1 interferon diagnostic |
JP7522749B2 (en) | 2019-02-15 | 2024-07-25 | アストラゼネカ・アクチエボラーグ | Type I Interferon-Mediated Disorders |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1981002899A1 (en) * | 1980-04-11 | 1981-10-15 | D Secher | Monoclonal antibody |
WO1982001773A1 (en) * | 1980-11-07 | 1982-05-27 | Secher David S | Assay for interferon |
FR2500754A1 (en) * | 1981-02-27 | 1982-09-03 | Hoffmann La Roche | MONOCLONAL ANTIBODIES |
-
1983
- 1983-02-04 GB GB838303165A patent/GB8303165D0/en active Pending
-
1984
- 1984-02-06 WO PCT/GB1984/000031 patent/WO1984003105A1/en not_active Application Discontinuation
- 1984-02-06 JP JP50076784A patent/JPS60500714A/en active Pending
- 1984-02-06 GB GB08423719A patent/GB2146351B/en not_active Expired
- 1984-02-06 EP EP19840900633 patent/EP0134803A1/en not_active Ceased
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1981002899A1 (en) * | 1980-04-11 | 1981-10-15 | D Secher | Monoclonal antibody |
WO1982001773A1 (en) * | 1980-11-07 | 1982-05-27 | Secher David S | Assay for interferon |
FR2500754A1 (en) * | 1981-02-27 | 1982-09-03 | Hoffmann La Roche | MONOCLONAL ANTIBODIES |
Also Published As
Publication number | Publication date |
---|---|
WO1984003105A1 (en) | 1984-08-16 |
EP0134803A1 (en) | 1985-03-27 |
GB8303165D0 (en) | 1983-03-09 |
GB8423719D0 (en) | 1984-10-24 |
JPS60500714A (en) | 1985-05-16 |
GB2146351B (en) | 1986-10-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |