GB2128998B - Pharmaceutical compositions of iron complexes of 3 hydroxy-4-pyrone - Google Patents

Pharmaceutical compositions of iron complexes of 3 hydroxy-4-pyrone

Info

Publication number
GB2128998B
GB2128998B GB08327612A GB8327612A GB2128998B GB 2128998 B GB2128998 B GB 2128998B GB 08327612 A GB08327612 A GB 08327612A GB 8327612 A GB8327612 A GB 8327612A GB 2128998 B GB2128998 B GB 2128998B
Authority
GB
United Kingdom
Prior art keywords
pyrone
hydroxy
pharmaceutical compositions
iron complexes
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08327612A
Other languages
English (en)
Other versions
GB8327612D0 (en
GB2128998A (en
Inventor
Robert Charles Hider
George Kontoghiorghes
Michael Arthur Stockham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NAT RES DEV
National Research Development Corp UK
Original Assignee
NAT RES DEV
National Research Development Corp UK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NAT RES DEV, National Research Development Corp UK filed Critical NAT RES DEV
Publication of GB8327612D0 publication Critical patent/GB8327612D0/en
Publication of GB2128998A publication Critical patent/GB2128998A/en
Application granted granted Critical
Publication of GB2128998B publication Critical patent/GB2128998B/en
Priority claimed from CA000524044A external-priority patent/CA1338496C/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
GB08327612A 1982-10-22 1983-10-14 Pharmaceutical compositions of iron complexes of 3 hydroxy-4-pyrone Expired GB2128998B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8230150 1982-10-22
CA000446932A CA1243606A (en) 1982-10-22 1984-02-07 Pharmaceutical compositions containing iron complexes of 3-hydroxy-4-pyrones
CA000524044A CA1338496C (en) 1982-10-22 1986-11-28 Pharmaceutically active iron complexes of 3-hydroxy-4-pyrones

Publications (3)

Publication Number Publication Date
GB8327612D0 GB8327612D0 (en) 1983-11-16
GB2128998A GB2128998A (en) 1984-05-10
GB2128998B true GB2128998B (en) 1986-07-16

Family

ID=27167414

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08327612A Expired GB2128998B (en) 1982-10-22 1983-10-14 Pharmaceutical compositions of iron complexes of 3 hydroxy-4-pyrone

Country Status (8)

Country Link
US (3) US4575502A (enExample)
EP (1) EP0107458B1 (enExample)
JP (2) JPS5993071A (enExample)
AU (1) AU567915B2 (enExample)
CA (1) CA1243606A (enExample)
DK (1) DK485383D0 (enExample)
GB (1) GB2128998B (enExample)
HK (1) HK16090A (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128998B (en) * 1982-10-22 1986-07-16 Nat Res Dev Pharmaceutical compositions of iron complexes of 3 hydroxy-4-pyrone
USRE37534E1 (en) 1982-10-22 2002-01-29 Btg International Limited Pharmaceutical compositions
US4708862A (en) * 1983-02-22 1987-11-24 Xoma Corporation Radioimmuno detection of human cancers using anti-tumor monoclonal antibody
US4912118A (en) * 1983-09-23 1990-03-27 National Research Development Corporation Pharmaceutical compositions
GB8329043D0 (en) * 1983-10-31 1983-11-30 Hider R C Pharmaceutical compositions
GB8410290D0 (en) * 1984-04-19 1984-05-31 Callingham B A Pharmaceutical compositions
US5177068A (en) * 1984-04-19 1993-01-05 National Research Development Corporation Pharmaceutical compositions
GB8410289D0 (en) * 1984-04-19 1984-05-31 Callingham B A Pharmaceutical compositions
GB8615041D0 (en) * 1986-06-20 1986-07-23 Silver J Pharmaceutical compositions
US6004951A (en) * 1989-11-22 1999-12-21 Bernstein; Lawrence Richard Administration of gallium complexes of 3-hydroxy-4-pyrones to provide physiologically active gallium levels in a mammalian individual
US5574027A (en) * 1989-11-22 1996-11-12 Bernstein; Lawrence R. Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
US5258376A (en) * 1989-11-22 1993-11-02 Bernstein Lawrence R Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
GB9006522D0 (en) * 1990-03-23 1990-05-23 Hider Robert C Metal complexes
AU7981791A (en) * 1990-05-24 1991-12-10 Fujisawa, Inc. Orally administrable gallium compositions and methods of treatment therewith
US5298525A (en) * 1992-11-23 1994-03-29 University Technologies International, Inc. Diabetes prevention and treatment
EP0833627B1 (en) 1995-06-10 2004-08-18 Vitra Pharmaceuticals Ltd. Iron compounds, compositions, methods of making the same and uses thereof
US5906978A (en) 1996-08-14 1999-05-25 Hemocleanse, Inc. Method for iron delivery to a patient by transfer from dialysate
GB9621273D0 (en) 1996-10-11 1996-11-27 Cortecs Ltd Therapeutic method
WO2000016736A1 (en) * 1998-09-23 2000-03-30 Unilever N.V. Oral care compositions
PT1072198E (pt) * 1999-07-28 2008-06-17 Swiss Caps Rechte & Lizenzen Preparado, especialmente para utilização como medicamento e/ou como suplemento alimentar
US6767741B1 (en) 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
CA2421410C (en) 2000-09-19 2009-11-10 Vitra Pharmaceuticals Limited Iron compositions
US7073271B2 (en) * 2002-02-14 2006-07-11 Faro Technologies Inc. Portable coordinate measurement machine
RU2209062C1 (ru) * 2002-03-19 2003-07-27 Институт физиологии им. И.П.Павлова РАН Вещество, обладающее седативным действием
GB0211500D0 (en) 2002-05-18 2002-06-26 Vitra Pharmaceuticals Ltd Method of forming iron hydroxypyrone compounds
JP4950890B2 (ja) * 2004-09-13 2012-06-13 ギリアード サイエンシーズ， インコーポレイテッド 動物に対する鉄の送達
BRPI0515847A (pt) * 2004-10-08 2008-08-12 Unilever Nv uso de um complexo de ferro, composição alimentìcia, gênero alimentìcio fortificado com ferro, composição de bebida, bebida fortificada com ferro, suplemento alimentar e composição farmacêutica
US7857977B2 (en) * 2005-07-12 2010-12-28 Rockwell Medical Technologies, Inc. Packaging of ferric pyrophosphate for dialysis
US7816404B2 (en) 2007-07-20 2010-10-19 Rockwell Medical Technologies, Inc. Methods for the preparation and use of ferric pyrophosphate citrate chelate compositions
GB0808835D0 (en) * 2008-05-15 2008-06-18 Vitra Pharmaceuticals Ltd Therapeutic compositions
TW201111392A (en) 2009-06-16 2011-04-01 Schering Corp Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof
AU2011231710B2 (en) 2010-03-23 2013-07-25 Vifor (International) Ag Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias
GB201101370D0 (en) 2011-01-27 2011-03-09 Iron Therapeutics Holdings Ag Process
CA2829240C (en) 2011-03-29 2016-11-22 Vifor (International) Ag Fe(iii) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias
AR086606A1 (es) 2011-05-31 2014-01-08 Vifor Int Ag Compuestos del complejo de fe(iii) para el tratamiento y profilaxis de los sintomas de la deficiencia de hierro y las anemias por deficiencia de hierro
RU2641030C2 (ru) 2012-12-21 2018-01-15 Вифор (Интернациональ) Аг Комплексные соединения трехвалентного железа для лечения и профилактики симптомов дефицита железа и железодефицитных анемий
GB201404390D0 (en) * 2014-03-12 2014-04-23 Iron Therapeutics Holdings Ag Composition
GB2531742B (en) * 2014-10-28 2016-10-05 Iron Therapeutics Holdings Ag Polymorphs of ferric maltol
IT202100018578A1 (it) * 2021-07-14 2023-01-14 Indena Spa Dispersione amorfa di maltolo ferrico e relativo processo di preparazione
US11661819B2 (en) 2021-08-03 2023-05-30 Baker Hughes Oilfield Operations Llc Valve, method and system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2904573A (en) * 1957-05-06 1959-09-15 Ortho Pharma Corp Ferrous citrate complex
US2865938A (en) * 1957-09-25 1958-12-23 Hyman Rosenstein Iron choline compound and production thereof
US3130204A (en) * 1962-02-07 1964-04-21 Pfizer & Co C Preparation of gamma-pyrones
FR2130M (fr) * 1962-04-25 1963-11-12 Rech S Appliquees Soc D Expl Médicament a base d'une solution aqueuse stable de chlorure ferreux et d'acide ascorbique.
DE1518098A1 (de) * 1963-09-19 1969-04-10 Pfizer & Co C Verfahren zur Herstellung von Pyromekonsaeurederivaten
US3821192A (en) * 1971-08-18 1974-06-28 Central Pharmacal Co Process for preparing an iron-saccharide complex
US4018937A (en) * 1972-12-14 1977-04-19 Rca Corporation Electron beam recording comprising polymer of 1-methylvinyl methyl ketone
US4058621A (en) * 1975-02-24 1977-11-15 Peter, Strong & Company, Inc. Iron complexes and foodstuffs containing them
DE2613500A1 (de) * 1975-04-01 1976-10-21 Procter & Gamble Mundpflegemittel und verfahren zur verhinderung von verfaerbungen der zaehne
US4018907A (en) * 1975-08-25 1977-04-19 General Foods Corporation Coloring food with iron-complexes
US4018934A (en) * 1975-08-25 1977-04-19 General Foods Corporation Stabilization of iron - complex colors
US4311691A (en) * 1979-10-09 1982-01-19 Fichera Anthony T Tobacco smoking inhibitor
GB2128998B (en) * 1982-10-22 1986-07-16 Nat Res Dev Pharmaceutical compositions of iron complexes of 3 hydroxy-4-pyrone

Also Published As

Publication number Publication date
JPH0336807B1 (enExample) 1991-06-03
EP0107458A1 (en) 1984-05-02
AU2455284A (en) 1985-08-15
US4575502A (en) 1986-03-11
AU567915B2 (en) 1987-12-10
GB8327612D0 (en) 1983-11-16
GB2128998A (en) 1984-05-10
US4861767A (en) 1989-08-29
JPS5993071A (ja) 1984-05-29
US4834983A (en) 1989-05-30
CA1243606A (en) 1988-10-25
HK16090A (en) 1990-03-09
DK485383D0 (da) 1983-10-21
EP0107458B1 (en) 1987-07-29
JPH0545589B2 (enExample) 1993-07-09
JPH03223274A (ja) 1991-10-02

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Legal Events

Date Code Title Description
7732 Case decided by the comptroller ** patent revoked (sect. 73(2)/1977)