GB2111491B - Aminofluorescein derivatives and their use in fluorescence polarization immunoassay - Google Patents

Aminofluorescein derivatives and their use in fluorescence polarization immunoassay

Info

Publication number
GB2111491B
GB2111491B GB08233403A GB8233403A GB2111491B GB 2111491 B GB2111491 B GB 2111491B GB 08233403 A GB08233403 A GB 08233403A GB 8233403 A GB8233403 A GB 8233403A GB 2111491 B GB2111491 B GB 2111491B
Authority
GB
United Kingdom
Prior art keywords
aminofluorescein
derivatives
fluorescence polarization
polarization immunoassay
immunoassay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08233403A
Other versions
GB2111491A (en
Inventor
Chao-Huei Jeffrey Wang
Stephen Denham Stroupe
Michael Ernest Jolley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of GB2111491A publication Critical patent/GB2111491A/en
Application granted granted Critical
Publication of GB2111491B publication Critical patent/GB2111491B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB08233403A 1981-12-11 1982-11-23 Aminofluorescein derivatives and their use in fluorescence polarization immunoassay Expired GB2111491B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32997581A 1981-12-11 1981-12-11

Publications (2)

Publication Number Publication Date
GB2111491A GB2111491A (en) 1983-07-06
GB2111491B true GB2111491B (en) 1985-08-21

Family

ID=23287816

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08233403A Expired GB2111491B (en) 1981-12-11 1982-11-23 Aminofluorescein derivatives and their use in fluorescence polarization immunoassay

Country Status (9)

Country Link
JP (1) JPS58113189A (en)
AU (1) AU558800B2 (en)
BE (1) BE895300A (en)
CA (1) CA1248086A (en)
DE (1) DE3245854C2 (en)
FR (1) FR2518096B1 (en)
GB (1) GB2111491B (en)
IT (1) IT1155424B (en)
NZ (1) NZ202613A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574184B1 (en) * 1984-11-30 1988-04-22 Centre Nat Rech Scient FLUORESCENT COMPOUNDS, DERIVATIVES OF (AMINO-4 DISULFONATO-3,6) NAPHTALIMIDE, THEIR APPLICATION TO IMMUNOLOGICAL ASSAYS IN POLARIZATION OF FLUORESCENCE
EP0201633A3 (en) * 1984-12-20 1989-02-22 Abbott Laboratories Substituted anilide compounds and their use
EP0199042A1 (en) * 1985-03-26 1986-10-29 Abbott Laboratories Procainamide assay, tracers, immunogens and antibodies
DE3682105D1 (en) * 1985-04-01 1991-11-28 Abbott Lab SAMPLE, TRACERS, IMMUNOGENIC AND ANTIBODIES OF ETHOSUXIMID.
EP0242847B1 (en) * 1986-04-25 1993-06-02 Abbott Laboratories Tracers for use in flecainide fluorescence polarization immunoassay
ATE155893T1 (en) * 1990-05-16 1997-08-15 Abbott Lab TEST FOR BARBITURATES, TRACERS, IMMUNOGENS, ANTIBODIES AND TEST KIT THEREOF
DE4143341C2 (en) * 1991-02-22 1995-05-18 Kernforschungsz Karlsruhe Method for producing an optical sensor
US5395933A (en) * 1992-08-07 1995-03-07 Eastman Kodak Company Carbamazepine hapten analogues
IT1298693B1 (en) * 1996-04-24 2000-01-12 Hoffmann La Roche 4'-METHYL SUBSTITUTED FLUORESCEIN DERIVATIVES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998943A (en) * 1973-10-02 1976-12-21 Syva Company Double receptor fluorescent immunoassay
US4160818A (en) * 1976-04-15 1979-07-10 Technicon Instruments Corporation Fluorimetric immunoassay for diphenylhydantoin

Also Published As

Publication number Publication date
IT8224689A1 (en) 1984-06-10
JPS58113189A (en) 1983-07-05
AU9088082A (en) 1983-06-16
IT1155424B (en) 1987-01-28
DE3245854C2 (en) 1996-11-14
FR2518096A1 (en) 1983-06-17
NZ202613A (en) 1985-12-13
AU558800B2 (en) 1987-02-12
BE895300A (en) 1983-06-09
CA1248086A (en) 1989-01-03
GB2111491A (en) 1983-07-06
IT8224689A0 (en) 1982-12-10
DE3245854A1 (en) 1983-06-23
FR2518096B1 (en) 1985-12-06

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19971123