GB2093023A - Substituted aliphatic secondary amines and their salts, pharmaceutical preparations containing them and their use - Google Patents

Substituted aliphatic secondary amines and their salts, pharmaceutical preparations containing them and their use Download PDF

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Publication number
GB2093023A
GB2093023A GB8203669A GB8203669A GB2093023A GB 2093023 A GB2093023 A GB 2093023A GB 8203669 A GB8203669 A GB 8203669A GB 8203669 A GB8203669 A GB 8203669A GB 2093023 A GB2093023 A GB 2093023A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
phenyl
unsubstituted
formula
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB8203669A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB2093023A publication Critical patent/GB2093023A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/60—Preparation of compounds containing amino groups bound to a carbon skeleton by condensation or addition reactions, e.g. Mannich reaction, addition of ammonia or amines to alkenes or to alkynes or addition of compounds containing an active hydrogen atom to Schiff's bases, quinone imines, or aziranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB8203669A 1981-02-12 1982-02-09 Substituted aliphatic secondary amines and their salts, pharmaceutical preparations containing them and their use Withdrawn GB2093023A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH93981 1981-02-12

Publications (1)

Publication Number Publication Date
GB2093023A true GB2093023A (en) 1982-08-25

Family

ID=4198692

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8203669A Withdrawn GB2093023A (en) 1981-02-12 1982-02-09 Substituted aliphatic secondary amines and their salts, pharmaceutical preparations containing them and their use

Country Status (17)

Country Link
US (1) US4448776A (enExample)
EP (1) EP0058373A1 (enExample)
JP (1) JPS57150642A (enExample)
KR (1) KR830008984A (enExample)
AU (1) AU8036682A (enExample)
BE (1) BE892100A (enExample)
DD (1) DD202144A5 (enExample)
DK (1) DK59382A (enExample)
FI (1) FI820419A7 (enExample)
GB (1) GB2093023A (enExample)
GR (1) GR75852B (enExample)
IE (1) IE820303L (enExample)
IL (1) IL64971A0 (enExample)
IT (1) IT8247762A0 (enExample)
NO (1) NO820405L (enExample)
PT (1) PT74414B (enExample)
ZA (1) ZA82876B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703095A (en) * 1992-11-13 1997-12-30 L'oreal Use of N-arylmethylene, ethylenediaminetriacetates, N-arymethylene iminodiacetates or N,N'-diarylmethylene ethylenediamineacetates against oxidative stress
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
GB0517740D0 (en) * 2005-08-31 2005-10-12 Novartis Ag Organic compounds
ES2880313T3 (es) 2014-06-16 2021-11-24 Univ Lille Compuestos, composición farmacéutica y su uso en el tratamiento de enfermedades neurodegenerativas

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2483434A (en) * 1946-04-08 1949-10-04 Parke Davis & Co Disubstituted amino-alkyl benzhydryl amines
GB752331A (en) * 1948-09-30 1956-07-11 Abbott Lab Improvements in or relating to n, n-disubstituted piperazines and process of preparing the same
US2627491A (en) * 1950-07-15 1953-02-03 Wyeth Corp Penicillin salts of substituted alkylene diamines
DE1008308B (de) * 1953-02-09 1957-05-16 Asta Werke Ag Chem Fab Verfahren zur Herstellung von ª‡[(ª‰-Dialkylamino-alkyl)-alkyl-amino]-phenyl-essigsaeure-isoamyl- und -n-nonylestern
GB786215A (en) * 1955-03-14 1957-11-13 Allen & Hanburys Ltd New diamines and salts thereof
GB863217A (en) * 1956-11-16 1961-03-22 Ciba Ltd Manufacture of new piperazo-[c]-pyridazines
US3013020A (en) * 1958-01-24 1961-12-12 Miles Lab N,n'-bis-phenyl-alkylene-diamines
GB872371A (en) * 1958-07-07 1961-07-05 Univ Kansas Reseach Foundation Benzyl amine compounds and means of obtaining the same
GB987438A (en) * 1961-10-10 1965-03-31 Frosst & Co Charles E N,n-disubstituted-1,3-diamino-propanes and 2-propanols
GB1025041A (en) * 1964-02-21 1966-04-06 Hoechst Ag Process for the manufacture of diphenylalkylamines
GB1109502A (en) * 1964-04-18 1968-04-10 Fisons Pharmaceuticals Ltd Substituted n-benzyl-ethylenediamines
US3501527A (en) * 1965-03-16 1970-03-17 Standard Oil Co Process for preparing alkaline earth salts of hydroxyarylalkyl amines
US3401224A (en) * 1965-06-14 1968-09-10 Barrett Paul Anthony Treatment of depression with nu-benzylpiperazine
US3483209A (en) * 1967-05-02 1969-12-09 Ciba Geigy Corp Aralkylamines
US3551492A (en) * 1967-10-31 1970-12-29 Ciba Geigy Corp N,n'-diaminoalkoxy-benzyl-diamino-alkanes and the salts thereof
US3876702A (en) * 1968-04-26 1975-04-08 Rudolf Theodor Petersen N,n-bis-(diphenylalkyl)-alkylendiamine and their salts
GB1405767A (en) * 1972-12-14 1975-09-10 Ethyl Corp Method formulation and pharmaceutical composition for reducing plasma lipid levels
DE2438288A1 (de) * 1974-08-09 1976-02-19 Knoll Ag Neue antiarrhythmika
US4091220A (en) * 1974-11-19 1978-05-23 Takeda Chemical Industries, Ltd. Morpholinocarbonyl alkyl N-benzylpiperazines
US4153794A (en) * 1974-11-19 1979-05-08 Takeda Chemical Industries, Ltd. N-Benzylpiperazines
FR2490963B1 (fr) * 1980-09-30 1986-04-18 Science Union & Cie Nouvelle composition therapeutique a action anti-ischemique contenant de la trimethoxy 2, 3, 4-benzyl 1-piperazine

Also Published As

Publication number Publication date
JPS57150642A (en) 1982-09-17
FI820419L (fi) 1982-08-13
IL64971A0 (en) 1982-04-30
PT74414A (de) 1982-03-01
ZA82876B (en) 1982-10-27
IT8247762A0 (it) 1982-02-10
BE892100A (fr) 1982-08-11
DK59382A (da) 1982-08-13
KR830008984A (ko) 1983-12-16
AU8036682A (en) 1982-08-19
DD202144A5 (de) 1983-08-31
GR75852B (enExample) 1984-08-02
EP0058373A1 (de) 1982-08-25
PT74414B (de) 1984-10-09
US4448776A (en) 1984-05-15
NO820405L (no) 1982-08-13
FI820419A7 (fi) 1982-08-13
IE820303L (en) 1982-08-12

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)