GB2027024B - Doxorubicin derivatives - Google Patents

Doxorubicin derivatives

Info

Publication number
GB2027024B
GB2027024B GB7926641A GB7926641A GB2027024B GB 2027024 B GB2027024 B GB 2027024B GB 7926641 A GB7926641 A GB 7926641A GB 7926641 A GB7926641 A GB 7926641A GB 2027024 B GB2027024 B GB 2027024B
Authority
GB
United Kingdom
Prior art keywords
doxorubicin derivatives
doxorubicin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7926641A
Other languages
English (en)
Other versions
GB2027024A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST INT PATHOLOGIE CELLULAIRE
Original Assignee
INST INT PATHOLOGIE CELLULAIRE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST INT PATHOLOGIE CELLULAIRE filed Critical INST INT PATHOLOGIE CELLULAIRE
Publication of GB2027024A publication Critical patent/GB2027024A/en
Application granted granted Critical
Publication of GB2027024B publication Critical patent/GB2027024B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB7926641A 1978-08-03 1979-07-31 Doxorubicin derivatives Expired GB2027024B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE869485 1978-08-03

Publications (2)

Publication Number Publication Date
GB2027024A GB2027024A (en) 1980-02-13
GB2027024B true GB2027024B (en) 1983-04-27

Family

ID=3861689

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7926641A Expired GB2027024B (en) 1978-08-03 1979-07-31 Doxorubicin derivatives

Country Status (6)

Country Link
US (1) US4296105A (https=)
JP (1) JPS5522697A (https=)
CA (1) CA1115694A (https=)
FR (1) FR2432525A1 (https=)
GB (1) GB2027024B (https=)
NL (1) NL191150C (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
BE1008581A3 (fr) * 1994-08-19 1996-06-04 Wallone Region Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
WO1996005863A1 (fr) * 1994-08-19 1996-02-29 La Region Wallonne Composes, composition pharmaceutique et dispositif de diagnostic les comprenant et leur utilisation
JP2543434Y2 (ja) * 1996-04-15 1997-08-06 マツダ株式会社 エンジンの排気管構造
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US20040081659A1 (en) * 1997-12-02 2004-04-29 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
ID24735A (id) * 1997-12-02 2000-08-03 Merck & Co Ltd Konjugat-konjugat yang berguna pada pengobatan kanker prostat
ZA9810974B (en) * 1997-12-02 1999-06-03 Merck & Co Inc Conjugates useful in the treatment of prostate cancer
US6174858B1 (en) 1998-11-17 2001-01-16 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
JP2003512339A (ja) 1999-10-19 2003-04-02 メルク エンド カムパニー インコーポレーテッド 前立腺癌の治療に有用な複合体
CA2387901A1 (en) 1999-10-27 2001-05-03 Merck & Co., Inc. Salt form of a conjugate useful in the treatment of prostate cancer
CA2388844A1 (en) * 1999-11-12 2001-05-25 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
AU2001266853B2 (en) * 2000-06-14 2005-02-17 Medarex, Inc. Prodrug compounds with an oligopeptide having an isoleucine residue
AU2001286727A1 (en) * 2000-08-24 2002-03-04 Coulter Pharmaceutical, Inc. Prodrugs activated by plasmin and their use in cancer chemotherapy
US20030232760A1 (en) * 2001-09-21 2003-12-18 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
CN101134119A (zh) 2002-05-24 2008-03-05 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
EP1542739B1 (en) 2002-09-26 2008-12-10 Angiotech International Ag Perivascular wraps
AU2003300076C1 (en) 2002-12-30 2010-03-04 Angiotech International Ag Drug delivery from rapid gelling polymer composition
CA2536242A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Implantable sensors and implantable pumps and anti-scarring agents
WO2005072061A2 (en) * 2004-02-02 2005-08-11 Biosight Ltd. Conjugates for cancer therapy and diagnosis
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
US9789209B2 (en) 2013-03-14 2017-10-17 The Regents Of The University Of California, Berke Activatable membrane-interacting peptides and methods of use
US12064445B2 (en) 2015-12-03 2024-08-20 Biosight Ltd. Cytarabine conjugates for cancer therapy
US12071450B2 (en) 2015-12-03 2024-08-27 Biosight Ltd. Salts of conjugates for cancer therapy
AU2016362239B2 (en) 2015-12-03 2021-03-25 BioCytara Ltd. Salts of conjugates for cancer therapy
US11058701B2 (en) 2015-12-03 2021-07-13 Biosight Ltd. Cytarabine conjugates for cancer therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1578734A (https=) * 1967-11-28 1969-08-22
FR7164M (https=) * 1968-02-22 1969-08-04
FI51808C (fi) * 1968-07-15 1977-04-12 Rhone Poulenc Sa Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi.
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4012448A (en) * 1976-01-15 1977-03-15 Stanford Research Institute Synthesis of adriamycin and 7,9-epiadriamycin
FR2430425A1 (fr) * 1978-07-07 1980-02-01 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
NL191150C (nl) 1995-02-16
FR2432525A1 (fr) 1980-02-29
FR2432525B1 (https=) 1983-12-02
JPS6259715B2 (https=) 1987-12-12
US4296105A (en) 1981-10-20
NL191150B (nl) 1994-09-16
CA1115694A (en) 1982-01-05
NL7905953A (nl) 1980-02-05
GB2027024A (en) 1980-02-13
JPS5522697A (en) 1980-02-18

Similar Documents

Publication Publication Date Title
GB2027024B (en) Doxorubicin derivatives
GB2033893B (en) Tetrazolylalkoxycarbostyril derivatives
IL61507A0 (en) Pyridinesulfonylisocyanate derivatives
GB2012759B (en) Thienohydantoin derivatives
PH15672A (en) Spiro-polycyclicimidazolidinedione derivatives
IL56430A0 (en) Prostaglanding derivatives
GB2022079B (en) L-leucyl-4-hydroxyanilide derivatives
IL56702A0 (en) Aldamolamine derivatives
GB2018757B (en) 3-phenyltetrahydropyridine derivatives
GB2038326B (en) Acylaniline derivatives
GB2017708B (en) Steroid-spirooxazolidinone derivatives
GB2036744B (en) Eburnane derivatives
GB2019843B (en) N-alkenylmoranoline derivatives
GB2017691B (en) 2-hydroxymethyl-pyrazine derivatives
ZA787312B (en) Arylaminoimidazoline derivatives
GB2032420B (en) Daunorubicin derivatives
GB2024806B (en) Onomycin derivatives
GB2052477B (en) Carbamoyl-piperazine derivatives
GB2023574B (en) N-cyano-azomethine derivatives
GB2013187B (en) Phenylpyrol derivatives
PH14560A (en) Oxadiazolothiazine derivatives
PT69794A (en) Sephalosporin derivatives
GB2013654B (en) Benziosothiazole derivatives
GB2037764B (en) 7-methoxycepgalosporin derivatives
GB2044251B (en) Phenoxypropanolamine derivatives

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950731