GB202201927D0 - Artificial microrna construct - Google Patents
Artificial microrna constructInfo
- Publication number
- GB202201927D0 GB202201927D0 GBGB2201927.7A GB202201927A GB202201927D0 GB 202201927 D0 GB202201927 D0 GB 202201927D0 GB 202201927 A GB202201927 A GB 202201927A GB 202201927 D0 GB202201927 D0 GB 202201927D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- artificial microrna
- microrna construct
- construct
- artificial
- microrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
- C12N2310/141—MicroRNAs, miRNAs
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB2201927.7A GB202201927D0 (en) | 2022-02-14 | 2022-02-14 | Artificial microrna construct |
PCT/EP2023/053529 WO2023152382A1 (en) | 2022-02-14 | 2023-02-13 | Artificial microrna construct |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB2201927.7A GB202201927D0 (en) | 2022-02-14 | 2022-02-14 | Artificial microrna construct |
Publications (1)
Publication Number | Publication Date |
---|---|
GB202201927D0 true GB202201927D0 (en) | 2022-03-30 |
Family
ID=80820881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB2201927.7A Ceased GB202201927D0 (en) | 2022-02-14 | 2022-02-14 | Artificial microrna construct |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB202201927D0 (en) |
WO (1) | WO2023152382A1 (en) |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
US7446190B2 (en) | 2002-05-28 | 2008-11-04 | Sloan-Kettering Institute For Cancer Research | Nucleic acids encoding chimeric T cell receptors |
WO2018009923A1 (en) * | 2016-07-08 | 2018-01-11 | F1 Oncology, Inc. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
CN107937428B (en) * | 2017-11-28 | 2021-08-06 | 马晓冬 | Construction method of carrier integrating functions of microRNA and CAR |
WO2019186274A2 (en) * | 2018-03-30 | 2019-10-03 | University Of Geneva | Micro rna expression constructs and uses thereof |
WO2020193628A1 (en) * | 2019-03-25 | 2020-10-01 | Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft | Enhancement of cytolytic t-cell activity by inhibiting ebag9 |
EP4332115A2 (en) * | 2019-04-03 | 2024-03-06 | Precision Biosciences, Inc. | Genetically-modified immune cells comprising a microrna-adapted shrna (shrnamir) |
EP3963076A1 (en) * | 2019-05-02 | 2022-03-09 | Celyad | Cells with multiplexed inhibitory rna |
CN110760001B (en) * | 2019-07-29 | 2023-03-24 | 浙江启新生物技术有限公司 | Construction and application of chimeric antigen receptor T cell secreted by GM-CSF knockdown and neutralizing single-chain antibody thereof |
CN112239759A (en) * | 2020-10-28 | 2021-01-19 | 重庆斯德姆生物技术有限公司 | MicroRNA for knocking down PD1 gene expression and construction of chimeric antigen receptor-T/NK cell thereof |
EP4274898A2 (en) * | 2021-01-11 | 2023-11-15 | Precigen, Inc. | Chimeric receptor therapy |
AU2022262648A1 (en) * | 2021-04-23 | 2023-11-09 | Baylor College Of Medicine | Car nkts expressing artificial micro rna-embedded shrna for downregulation of mhc class i & ii expression |
CN113337544B (en) * | 2021-07-05 | 2023-04-14 | 北京中医药大学 | Retroviral vector expressing CAR and microrna and uses thereof |
-
2022
- 2022-02-14 GB GBGB2201927.7A patent/GB202201927D0/en not_active Ceased
-
2023
- 2023-02-13 WO PCT/EP2023/053529 patent/WO2023152382A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2023152382A1 (en) | 2023-08-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |