GB2017082B - 5-fluorouracil derivatives process for their production and pharmaceuticals containing them - Google Patents

5-fluorouracil derivatives process for their production and pharmaceuticals containing them

Info

Publication number
GB2017082B
GB2017082B GB7902010A GB7902010A GB2017082B GB 2017082 B GB2017082 B GB 2017082B GB 7902010 A GB7902010 A GB 7902010A GB 7902010 A GB7902010 A GB 7902010A GB 2017082 B GB2017082 B GB 2017082B
Authority
GB
United Kingdom
Prior art keywords
production
pharmaceuticals containing
fluorouracil derivatives
derivatives process
fluorouracil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7902010A
Other versions
GB2017082A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elkawi AG
Original Assignee
Elkawi AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elkawi AG filed Critical Elkawi AG
Publication of GB2017082A publication Critical patent/GB2017082A/en
Application granted granted Critical
Publication of GB2017082B publication Critical patent/GB2017082B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
GB7902010A 1978-03-09 1979-01-19 5-fluorouracil derivatives process for their production and pharmaceuticals containing them Expired GB2017082B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH254978A CH633280A5 (en) 1978-03-09 1978-03-09 5-FLUORURACIL DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS.

Publications (2)

Publication Number Publication Date
GB2017082A GB2017082A (en) 1979-10-03
GB2017082B true GB2017082B (en) 1982-07-21

Family

ID=4236289

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7902010A Expired GB2017082B (en) 1978-03-09 1979-01-19 5-fluorouracil derivatives process for their production and pharmaceuticals containing them

Country Status (5)

Country Link
JP (1) JPS54130586A (en)
CH (1) CH633280A5 (en)
DE (1) DE2854008A1 (en)
FR (1) FR2419288A1 (en)
GB (1) GB2017082B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5668674A (en) * 1979-11-08 1981-06-09 Shionogi & Co Ltd 5-fluorouracil derivative
JPS5738774A (en) * 1980-08-19 1982-03-03 Chugai Pharmaceut Co Ltd Uracil derivative and its preparation
JPS57179188A (en) * 1981-04-28 1982-11-04 Shionogi & Co Ltd 5-fluorouracil derivative
JP2005513156A (en) * 2001-12-31 2005-05-12 ファエンドォラー,ハンス,ロドルフ Long-chain fatty alcohol substituents in antineoplastic drugs
EP1939186A1 (en) * 2006-12-22 2008-07-02 Sulfidris S.r.l. 5-Fluorouracil derivatives and their use for the treatment of cancer
JP2011231015A (en) * 2008-08-29 2011-11-17 Taiho Yakuhin Kogyo Kk Novel uracil compound having nitrogenated heterocyclic ring or salt thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5331874B2 (en) * 1973-08-11 1978-09-05
JPS5119778A (en) * 1974-08-09 1976-02-17 Mitsui Seiyaku Kogyo Kk 11 chikan 55 furuororashiruruino seizoho

Also Published As

Publication number Publication date
JPS54130586A (en) 1979-10-09
FR2419288B1 (en) 1982-11-05
CH633280A5 (en) 1982-11-30
GB2017082A (en) 1979-10-03
DE2854008A1 (en) 1979-09-13
FR2419288A1 (en) 1979-10-05

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee