GB201706090D0 - Methods for adeno-associated viral vector production - Google Patents

Methods for adeno-associated viral vector production

Info

Publication number
GB201706090D0
GB201706090D0 GBGB1706090.6A GB201706090A GB201706090D0 GB 201706090 D0 GB201706090 D0 GB 201706090D0 GB 201706090 A GB201706090 A GB 201706090A GB 201706090 D0 GB201706090 D0 GB 201706090D0
Authority
GB
United Kingdom
Prior art keywords
adeno
methods
viral vector
associated viral
vector production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1706090.6A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Intellectual Property Development Ltd
Original Assignee
GlaxoSmithKline Intellectual Property Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Intellectual Property Development Ltd filed Critical GlaxoSmithKline Intellectual Property Development Ltd
Priority to GBGB1706090.6A priority Critical patent/GB201706090D0/en
Publication of GB201706090D0 publication Critical patent/GB201706090D0/en
Priority to PCT/EP2018/059918 priority patent/WO2018192982A2/en
Priority to CN201880040553.6A priority patent/CN110785495A/en
Priority to JP2019556592A priority patent/JP2020517238A/en
Priority to EP18724467.8A priority patent/EP3612635A2/en
Priority to BR112019021595-6A priority patent/BR112019021595A2/en
Priority to GB1806319.8A priority patent/GB2566572B/en
Priority to CA3058970A priority patent/CA3058970A1/en
Priority to US15/955,992 priority patent/US10858631B2/en
Priority to US17/097,111 priority patent/US20210062161A1/en
Priority to JP2023035225A priority patent/JP2023081975A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB1706090.6A 2017-04-18 2017-04-18 Methods for adeno-associated viral vector production Ceased GB201706090D0 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
GBGB1706090.6A GB201706090D0 (en) 2017-04-18 2017-04-18 Methods for adeno-associated viral vector production
US15/955,992 US10858631B2 (en) 2017-04-18 2018-04-18 Methods for adeno-associated viral vector production
EP18724467.8A EP3612635A2 (en) 2017-04-18 2018-04-18 Methods for adeno-associated viral vector production
CN201880040553.6A CN110785495A (en) 2017-04-18 2018-04-18 Method for producing adeno-associated virus vector
JP2019556592A JP2020517238A (en) 2017-04-18 2018-04-18 Method for producing adeno-associated virus vector
PCT/EP2018/059918 WO2018192982A2 (en) 2017-04-18 2018-04-18 Methods for adeno-associated viral vector production
BR112019021595-6A BR112019021595A2 (en) 2017-04-18 2018-04-18 ADENO-ASSOCIATED VIRUS-PRODUCING CELL, NUCLEIC ACID VECTOR, METHODS FOR PRODUCING A STABLE PACKAGING OF ADEN-ASSOCIATED VIRUSES OF ADENO-ASSOCIATED VIRUS VIRUS WITH COME DEOCOULATED WITH DEFECTIVE DETICTION OF COME DEOCRATED WITH DEFEATURE ASSOCIATED, AND, ADENO-ASSOCIATED VIRUS PARTICLE WITH REPLICATION DEFECT.
GB1806319.8A GB2566572B (en) 2017-04-18 2018-04-18 Methods for adeno-associated viral vector production
CA3058970A CA3058970A1 (en) 2017-04-18 2018-04-18 Methods for adeno-associated viral vector production
US17/097,111 US20210062161A1 (en) 2017-04-18 2020-11-13 Methods for Adeno-Associated Viral Vector Production
JP2023035225A JP2023081975A (en) 2017-04-18 2023-03-08 Method for adeno-associated viral vector production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1706090.6A GB201706090D0 (en) 2017-04-18 2017-04-18 Methods for adeno-associated viral vector production

Publications (1)

Publication Number Publication Date
GB201706090D0 true GB201706090D0 (en) 2017-05-31

Family

ID=58744405

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1706090.6A Ceased GB201706090D0 (en) 2017-04-18 2017-04-18 Methods for adeno-associated viral vector production
GB1806319.8A Active GB2566572B (en) 2017-04-18 2018-04-18 Methods for adeno-associated viral vector production

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1806319.8A Active GB2566572B (en) 2017-04-18 2018-04-18 Methods for adeno-associated viral vector production

Country Status (1)

Country Link
GB (2) GB201706090D0 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111511922A (en) * 2018-01-19 2020-08-07 牛津遗传学有限公司 Vectors for production of AAV particles

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202116794A (en) * 2019-07-23 2021-05-01 美商健生生物科技公司 Synthetic genetic elements for biomanufacture

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548286B1 (en) * 1997-04-14 2003-04-15 Cell Genesys, Inc. Methods for increasing the efficiency of recombinant AAV product
US6793926B1 (en) * 1999-05-27 2004-09-21 Genovo, Inc. Methods for production of a recombinant adeno-associated virus
DE10137283A1 (en) * 2001-08-01 2003-02-27 Deutsches Krebsforsch AAV vector packaging plasmids for helper virus-free production of pseudotyped AAV particles by single transfection
EP2451476A4 (en) * 2009-07-06 2013-07-03 Alnylam Pharmaceuticals Inc Cell-based bioprocessing
DE102013220859B4 (en) * 2013-10-15 2016-09-08 Plasmidfactory Gmbh & Co. Kg Minicircles with viral expression cassettes and their use to transform cells to produce recombinant viruses or viral gene vectors
GB201519303D0 (en) * 2015-11-02 2015-12-16 Imp Innovations Ltd Phagemid vector

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111511922A (en) * 2018-01-19 2020-08-07 牛津遗传学有限公司 Vectors for production of AAV particles
CN111511922B (en) * 2018-01-19 2023-06-09 牛津遗传学有限公司 Vectors for producing AAV particles

Also Published As

Publication number Publication date
GB2566572B (en) 2020-07-15
GB201806319D0 (en) 2018-05-30
GB2566572A (en) 2019-03-20

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)