GB2014574A - Lactam Compounds - Google Patents

Lactam Compounds

Info

Publication number
GB2014574A
GB2014574A GB7905381A GB7905381A GB2014574A GB 2014574 A GB2014574 A GB 2014574A GB 7905381 A GB7905381 A GB 7905381A GB 7905381 A GB7905381 A GB 7905381A GB 2014574 A GB2014574 A GB 2014574A
Authority
GB
United Kingdom
Prior art keywords
compounds
preparation
disclosed
beta
lactam compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7905381A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to GB7905381A priority Critical patent/GB2014574A/en
Publication of GB2014574A publication Critical patent/GB2014574A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2

Abstract

beta -Lactam compounds of the formulae <IMAGE> are disclosed in which R represents a carboxyl or esterified carboxyl group and X represents an sulphonyloxy group. Processes for preparing the compounds and intermediates of use in their preparation are also disclosed. The compounds are of value in the preparation of further beta -lactam compounds, for example of formulae <IMAGE> in which R is a carboxyl or esterified carboxyl group, and R<1> is the residue of a sulphur nucleophile. Compounds of formula (I) are also disclosed, together with processes for their preparation, pharmaceutical compositions containing them and intermediates of use in their preparation. The compounds of formula (I) are of value as antibiotics or as beta -lactamase inhibitors.
GB7905381A 1978-02-16 1979-02-15 Lactam Compounds Withdrawn GB2014574A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7905381A GB2014574A (en) 1978-02-16 1979-02-15 Lactam Compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB624178 1978-02-16
GB7905381A GB2014574A (en) 1978-02-16 1979-02-15 Lactam Compounds

Publications (1)

Publication Number Publication Date
GB2014574A true GB2014574A (en) 1979-08-30

Family

ID=26240546

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7905381A Withdrawn GB2014574A (en) 1978-02-16 1979-02-15 Lactam Compounds

Country Status (1)

Country Link
GB (1) GB2014574A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2449092A1 (en) * 1978-11-24 1980-09-12 Erba Farmitalia 7-OXO-4-THIA-1-AZA-BICYCLO- (3,2,0) -HEPTANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR2453162A1 (en) * 1979-04-06 1980-10-31 Erba Farmitalia PROCESS FOR THE PREPARATION OF 4-ACETOXY-AZETIDINE-2-ONE DERIVATIVES BY CONDENSATION WITH A B-THIOCETOESTER AND COMPOUNDS OBTAINED
US4282236A (en) 1979-11-07 1981-08-04 Beecham Group Limited β-Lactam antibacterial agents, their use in pharmaceutical compositions, and intermediates

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2449092A1 (en) * 1978-11-24 1980-09-12 Erba Farmitalia 7-OXO-4-THIA-1-AZA-BICYCLO- (3,2,0) -HEPTANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR2453162A1 (en) * 1979-04-06 1980-10-31 Erba Farmitalia PROCESS FOR THE PREPARATION OF 4-ACETOXY-AZETIDINE-2-ONE DERIVATIVES BY CONDENSATION WITH A B-THIOCETOESTER AND COMPOUNDS OBTAINED
US4282236A (en) 1979-11-07 1981-08-04 Beecham Group Limited β-Lactam antibacterial agents, their use in pharmaceutical compositions, and intermediates

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)