GB2013191A - A Process for the Production of 4-Aminobutyric Acid or its Derivatives - Google Patents

A Process for the Production of 4-Aminobutyric Acid or its Derivatives

Info

Publication number
GB2013191A
GB2013191A GB7901840A GB7901840A GB2013191A GB 2013191 A GB2013191 A GB 2013191A GB 7901840 A GB7901840 A GB 7901840A GB 7901840 A GB7901840 A GB 7901840A GB 2013191 A GB2013191 A GB 2013191A
Authority
GB
United Kingdom
Prior art keywords
group
substituent
aminobutyric acid
derivatives
nitrile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7901840A
Other versions
GB2013191B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to GB7901840A priority Critical patent/GB2013191B/en
Publication of GB2013191A publication Critical patent/GB2013191A/en
Application granted granted Critical
Publication of GB2013191B publication Critical patent/GB2013191B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

4-Aminobutyric acid or its derivatives may be readily produced by a new process comprising reacting a propionic acid compound containing a carboxamido substituent (-CONH2) on the 3-carbon atom and optionally containing one or more of hydroxyl substituent, protected or unprotected amino substituent and lower alkyl substituent on the 2- and/or 3-carbon atoms thereof, with an alkanoic acid anhydride or alkanoic acid halide in a liquid tertiary amine such as pyridine to convert the carboxamido group into nitrile group, and then reducing the resultant nitrile compound with hydrogen to convert the nitrile group into aminomethyl group, and further optionally removing the residual amino-protecting group from the resultant 4-aminobutyric acid compound.
GB7901840A 1979-01-18 1979-01-18 Process for the production of 4 aminobutyric acid or its derivatives Expired GB2013191B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7901840A GB2013191B (en) 1979-01-18 1979-01-18 Process for the production of 4 aminobutyric acid or its derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7901840A GB2013191B (en) 1979-01-18 1979-01-18 Process for the production of 4 aminobutyric acid or its derivatives

Publications (2)

Publication Number Publication Date
GB2013191A true GB2013191A (en) 1979-08-08
GB2013191B GB2013191B (en) 1982-08-18

Family

ID=10502589

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7901840A Expired GB2013191B (en) 1979-01-18 1979-01-18 Process for the production of 4 aminobutyric acid or its derivatives

Country Status (1)

Country Link
GB (1) GB2013191B (en)

Also Published As

Publication number Publication date
GB2013191B (en) 1982-08-18

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960118