GB201115937D0 - 18F-labelled compounds for use as positron emission imaging agents - Google Patents
18F-labelled compounds for use as positron emission imaging agentsInfo
- Publication number
- GB201115937D0 GB201115937D0 GB201115937A GB201115937A GB201115937D0 GB 201115937 D0 GB201115937 D0 GB 201115937D0 GB 201115937 A GB201115937 A GB 201115937A GB 201115937 A GB201115937 A GB 201115937A GB 201115937 D0 GB201115937 D0 GB 201115937D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- positron emission
- imaging
- compounds
- disease
- imaging agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The present invention relates generally to the field of diagnostic methods. More specifically, the present invention pertains to certain 18F-labelled barbiturate compounds of the following formula (collectively referred to herein as "18F-fluorinated barbiturate compounds" and "18FBAR compounds") that bind to metals, for example, metals associated with protein aggregates, and as such are useful as imaging agents for positron emission imaging (e.g., positron emission tomography (PET) imaging) used in the diagnosis and monitoring of conditions involving these aggregates, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD). These compounds also bind strongly to GABAA receptors and hence are also useful as imaging agents for positron emission tomography (PET) imaging used in the diagnosis, monitoring and study of diseases involving dis-regulation of these receptors, including epilepsy, schizophrenia, and mood disorders (e.g., anxiety).
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201115937A GB201115937D0 (en) | 2011-09-14 | 2011-09-14 | 18F-labelled compounds for use as positron emission imaging agents |
| PCT/GB2012/052206 WO2013038153A1 (en) | 2011-09-14 | 2012-09-07 | 18f-labelled barbiturate compounds for use as positron emission imaging agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201115937A GB201115937D0 (en) | 2011-09-14 | 2011-09-14 | 18F-labelled compounds for use as positron emission imaging agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201115937D0 true GB201115937D0 (en) | 2011-10-26 |
Family
ID=44908608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB201115937A Ceased GB201115937D0 (en) | 2011-09-14 | 2011-09-14 | 18F-labelled compounds for use as positron emission imaging agents |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB201115937D0 (en) |
| WO (1) | WO2013038153A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018152339A1 (en) * | 2017-02-17 | 2018-08-23 | Yale University | Radiolabeled pharmaceuticals and methods of making and using same |
| CN113201007A (en) * | 2021-05-31 | 2021-08-03 | 四川大学华西医院 | Fluorescent probe for detecting fluorine ions, application thereof and method for detecting fluorine ions in sample to be detected |
| CN114479101B (en) * | 2022-01-22 | 2023-01-17 | 中北大学 | Supramolecular gel composition |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1989A (en) | 1841-02-20 | Stump-extractor | ||
| GB1073299A (en) | 1964-08-21 | 1967-06-21 | Aspro Nicholas Ltd | Improvements in or relating to the manufacture of barbituric acid derivatives |
| US4833148A (en) | 1987-04-09 | 1989-05-23 | Washington University | Method of using alkenyl- or alkynyl-substituted thiobarbiturates to reduce neurotoxic injury |
| JP2002519802A (en) | 1998-06-26 | 2002-07-02 | カード テック， インコーポレイテッド | Data system having a support surface for reproducing a data head |
| US6257759B1 (en) | 1998-06-26 | 2001-07-10 | Medical Indicators, Inc. | Liquid crystal thermometer |
| CN1896084A (en) | 2002-01-30 | 2007-01-17 | 塔罗制药工业有限公司 | Non-sedating barbituric acid derivatives |
| NI200300045A (en) | 2002-04-26 | 2005-07-08 | Pfizer Prod Inc | INHIBITORS OF TRIARILOXIARILOXIPIRIMIDIN-2,4,6-METALOPROTEINASE TRION. |
| GB0223249D0 (en) | 2002-10-08 | 2002-11-13 | Amersham Plc | Improved imaging agents |
-
2011
- 2011-09-14 GB GB201115937A patent/GB201115937D0/en not_active Ceased
-
2012
- 2012-09-07 WO PCT/GB2012/052206 patent/WO2013038153A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013038153A1 (en) | 2013-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |