GB2006777A - Platinum-Amine Complexes - Google Patents
Platinum-Amine ComplexesInfo
- Publication number
- GB2006777A GB2006777A GB7841109A GB7841109A GB2006777A GB 2006777 A GB2006777 A GB 2006777A GB 7841109 A GB7841109 A GB 7841109A GB 7841109 A GB7841109 A GB 7841109A GB 2006777 A GB2006777 A GB 2006777A
- Authority
- GB
- United Kingdom
- Prior art keywords
- platinum
- same
- present
- carboxylate
- ordination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052697 platinum Inorganic materials 0.000 abstract 3
- 201000011510 cancer Diseases 0.000 abstract 2
- 150000007942 carboxylates Chemical class 0.000 abstract 2
- 229910002651 NO3 Inorganic materials 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- -1 aliphatic amines Chemical class 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical class O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention relates to new platinum co-ordination compounds, to pharmaceutical compositions containing them and to their use in the treatment of malignant tumours or malignant neoplasms. In particular a compound according to the present invention comprises a cis co-ordination compound of platinum, having the structures: <IMAGE> in which X and Y are the same or different ligands selected from sulphate, phosphate, nitrate, carboxylate, substituted carboxylate and water and A and B are the same or different branched-chain aliphatic amines co-ordinated to the Pt through their N atoms, such that the platinum is present at Pt<2+>.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7841109A GB2006777B (en) | 1977-10-19 | 1978-10-18 | Compositions containing platinum |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4349277 | 1977-10-19 | ||
| GB7841109A GB2006777B (en) | 1977-10-19 | 1978-10-18 | Compositions containing platinum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2006777A true GB2006777A (en) | 1979-05-10 |
| GB2006777B GB2006777B (en) | 1982-10-27 |
Family
ID=26265169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7841109A Expired GB2006777B (en) | 1977-10-19 | 1978-10-18 | Compositions containing platinum |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2006777B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2140804A (en) * | 1983-06-01 | 1984-12-05 | Shionogi & Co | Glycolic acid type platinum complexes |
-
1978
- 1978-10-18 GB GB7841109A patent/GB2006777B/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2140804A (en) * | 1983-06-01 | 1984-12-05 | Shionogi & Co | Glycolic acid type platinum complexes |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2006777B (en) | 1982-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19951018 |