GB2006213A - Platinum-amine complexes - Google Patents
Platinum-amine complexesInfo
- Publication number
- GB2006213A GB2006213A GB7841110A GB7841110A GB2006213A GB 2006213 A GB2006213 A GB 2006213A GB 7841110 A GB7841110 A GB 7841110A GB 7841110 A GB7841110 A GB 7841110A GB 2006213 A GB2006213 A GB 2006213A
- Authority
- GB
- United Kingdom
- Prior art keywords
- platinum
- same
- groups
- halogenoid
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002577 pseudohalo group Chemical group 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 229910052697 platinum Inorganic materials 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- XLJMAIOERFSOGZ-UHFFFAOYSA-M cyanate Chemical compound [O-]C#N XLJMAIOERFSOGZ-UHFFFAOYSA-M 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention relates to new platinum co-ordination compounds, to pharmaceutical compositions containing them and to their use in the treatment of malignant tumours or malignant neoplasms. In particular a compound according to the present invention comprises a co-ordination compound of platinum having the structure:- <IMAGE> in which X and Y are halogenoid groups which are the same or different and are preferably both chloride but may be other halide or pseudohalide such as cyanate, thiocyanate and azide, the Z groups are the same and are either hydroxy or halogenoid, preferably chloride, and A and B are the same or different alicyclic amine groups co-ordinated to the Pt through their N atoms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7841110A GB2006213A (en) | 1977-10-19 | 1978-10-18 | Platinum-amine complexes |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4349077 | 1977-10-19 | ||
| GB7841110A GB2006213A (en) | 1977-10-19 | 1978-10-18 | Platinum-amine complexes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB2006213A true GB2006213A (en) | 1979-05-02 |
Family
ID=26265166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7841110A Pending GB2006213A (en) | 1977-10-19 | 1978-10-18 | Platinum-amine complexes |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2006213A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0343772A2 (en) * | 1988-05-26 | 1989-11-29 | Agency Of Industrial Science And Technology | Process for preparing platinum green complex |
| US5196555A (en) * | 1989-10-17 | 1993-03-23 | Bristol-Myers Squibb Company | Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity |
-
1978
- 1978-10-18 GB GB7841110A patent/GB2006213A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0343772A2 (en) * | 1988-05-26 | 1989-11-29 | Agency Of Industrial Science And Technology | Process for preparing platinum green complex |
| EP0343772A3 (en) * | 1988-05-26 | 1990-10-31 | Agency Of Industrial Science And Technology | Process for preparing platinum green complex |
| US5196555A (en) * | 1989-10-17 | 1993-03-23 | Bristol-Myers Squibb Company | Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity |
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