GB2000784A - Analgestic Polypeptides - Google Patents

Analgestic Polypeptides

Info

Publication number
GB2000784A
GB2000784A GB7828644A GB7828644A GB2000784A GB 2000784 A GB2000784 A GB 2000784A GB 7828644 A GB7828644 A GB 7828644A GB 7828644 A GB7828644 A GB 7828644A GB 2000784 A GB2000784 A GB 2000784A
Authority
GB
United Kingdom
Prior art keywords
polypeptides
analgestic
methyl
hydrogen
nhcnh2n
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7828644A
Other versions
GB2000784B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB2000784A publication Critical patent/GB2000784A/en
Application granted granted Critical
Publication of GB2000784B publication Critical patent/GB2000784B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The polypeptides have the formula: <IMAGE> in which R is hydrogen, methyl, allyl or cyclopropylmethyl; R<1> is hydrogen or methyl; and R<2> is -OH, -NH2 or NHCnH2n+1 where n is 1, 2, 3 or 4 and pharmaceutically acceptable salts thereof.g
GB7828644A 1977-07-05 1978-07-03 Analgesic polypetide Expired GB2000784B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81288577A 1977-07-05 1977-07-05

Publications (2)

Publication Number Publication Date
GB2000784A true GB2000784A (en) 1979-01-17
GB2000784B GB2000784B (en) 1982-01-20

Family

ID=25210879

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7828644A Expired GB2000784B (en) 1977-07-05 1978-07-03 Analgesic polypetide

Country Status (9)

Country Link
JP (1) JPS5416468A (en)
BE (1) BE868769A (en)
CH (1) CH634549A5 (en)
DE (1) DE2829610A1 (en)
FR (1) FR2396741A1 (en)
GB (1) GB2000784B (en)
IT (1) IT1096975B (en)
NL (1) NL7807247A (en)
ZA (1) ZA783838B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005121A (en) * 1979-09-20 1981-03-24 Erba Farmitalia ORGANICALLY ACTIVE PEPTIDES.
EP0076557B1 (en) * 1981-06-22 1985-11-13 Imperial Chemical Industries Plc Peptides and pseudopeptides in which the n terminus bears two substituents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51332A (en) * 1976-01-26 1980-09-16 Wellcome Found Peptides having a morphine-like effect, their preparation and pharmalceutical compositions containing them
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof

Also Published As

Publication number Publication date
IT1096975B (en) 1985-08-26
CH634549A5 (en) 1983-02-15
GB2000784B (en) 1982-01-20
BE868769A (en) 1979-01-05
DE2829610A1 (en) 1979-01-18
NL7807247A (en) 1979-01-09
FR2396741B1 (en) 1981-04-30
FR2396741A1 (en) 1979-02-02
ZA783838B (en) 1980-02-27
JPS5416468A (en) 1979-02-07
IT7825377A0 (en) 1978-07-05

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee