GB2000778A - Preparation of tetramisole intermediate - Google Patents

Preparation of tetramisole intermediate

Info

Publication number
GB2000778A
GB2000778A GB7829072A GB7829072A GB2000778A GB 2000778 A GB2000778 A GB 2000778A GB 7829072 A GB7829072 A GB 7829072A GB 7829072 A GB7829072 A GB 7829072A GB 2000778 A GB2000778 A GB 2000778A
Authority
GB
United Kingdom
Prior art keywords
tetramisole
preparation
hydroxyethylaminomethyl
hydroxyethylamino
thione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7829072A
Other versions
GB2000778B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmachim DSO
Original Assignee
Pharmachim DSO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachim DSO filed Critical Pharmachim DSO
Publication of GB2000778A publication Critical patent/GB2000778A/en
Application granted granted Critical
Publication of GB2000778B publication Critical patent/GB2000778B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

<IMAGE> d,1-1-(2-Hydroxyethyl)-4-phenyl-imidazolidine-2-thione, is obtained by reacting d,1- alpha -(2-hydroxyethylaminomethyl)-benzylamine with carbon disulphide and subjecting the resulting d,1-N-[2-(2-hydroxyethylamino)1-phenylethyl]-amide of dithiocarbonic acid to a cyclization process.
GB7829072A 1977-07-06 1978-07-06 Process for production of d,1-1-(2-hydroxyethyl) - 4 - phenyl - imidazolidine -2-thione and use thereof in the production of tetramisole Expired GB2000778B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG7700036812A BG25138A1 (en) 1977-07-06 1977-07-06 A method of obtaining of rs-(+/-)-2,3,5,6-tetrahydro-6-phenylimidazo-(2,1-b)-thiazol(tetramizol)

Publications (2)

Publication Number Publication Date
GB2000778A true GB2000778A (en) 1979-01-17
GB2000778B GB2000778B (en) 1982-04-07

Family

ID=3903588

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7829072A Expired GB2000778B (en) 1977-07-06 1978-07-06 Process for production of d,1-1-(2-hydroxyethyl) - 4 - phenyl - imidazolidine -2-thione and use thereof in the production of tetramisole

Country Status (13)

Country Link
JP (1) JPS5414996A (en)
BE (1) BE868743A (en)
BG (1) BG25138A1 (en)
CA (1) CA1100507A (en)
CS (1) CS199459B1 (en)
DE (1) DE2829823A1 (en)
ES (1) ES471355A1 (en)
FR (1) FR2396760A1 (en)
GB (1) GB2000778B (en)
IT (1) IT1174323B (en)
NL (1) NL7807267A (en)
SU (1) SU920056A1 (en)
YU (1) YU162178A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105130982B (en) * 2015-08-24 2017-04-05 华南农业大学 A kind of imidazoheterocycles dithiocarbamates and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3726894A (en) * 1971-06-24 1973-04-10 American Cyanamid Co The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione
US3865836A (en) * 1972-12-08 1975-02-11 Janssen Pharmaceutica Nv Bicyclic imidazoles

Also Published As

Publication number Publication date
SU920056A1 (en) 1982-04-15
GB2000778B (en) 1982-04-07
BE868743A (en) 1978-11-03
NL7807267A (en) 1979-01-09
IT7850169A0 (en) 1978-07-05
FR2396760B1 (en) 1981-12-18
FR2396760A1 (en) 1979-02-02
ES471355A1 (en) 1979-10-01
CA1100507A (en) 1981-05-05
DE2829823A1 (en) 1979-01-25
YU162178A (en) 1982-08-31
BG25138A1 (en) 1978-08-10
CS199459B1 (en) 1980-07-31
IT1174323B (en) 1987-07-01
JPS5414996A (en) 1979-02-03

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee