GB191100568A - Improvements in the Manufacture of Organic Derivatives of Arsenic Acid. - Google Patents
Improvements in the Manufacture of Organic Derivatives of Arsenic Acid.Info
- Publication number
- GB191100568A GB191100568A GB191100568DA GB191100568A GB 191100568 A GB191100568 A GB 191100568A GB 191100568D A GB191100568D A GB 191100568DA GB 191100568 A GB191100568 A GB 191100568A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- compounds
- diazo
- sodium
- arsenite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DJHGAFSJWGLOIV-UHFFFAOYSA-N Arsenic acid Chemical class O[As](O)(O)=O DJHGAFSJWGLOIV-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 8
- 150000008049 diazo compounds Chemical class 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 5
- 150000007513 acids Chemical class 0.000 abstract 4
- PTLRDCMBXHILCL-UHFFFAOYSA-M sodium arsenite Chemical compound [Na+].[O-][As]=O PTLRDCMBXHILCL-UHFFFAOYSA-M 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- SSQQBRZUIXIPIP-UHFFFAOYSA-N 5-diazo-2-nitrocyclohexa-1,3-diene Chemical compound [O-][N+](=O)C1=CCC(=[N+]=[N-])C=C1 SSQQBRZUIXIPIP-UHFFFAOYSA-N 0.000 abstract 2
- MKYHPYZPMNNCAT-UHFFFAOYSA-N 6-diazo-4-nitrocyclohexa-2,4-dien-1-ol Chemical compound [N+](=[N-])=C1C(C=CC(=C1)[N+](=O)[O-])O MKYHPYZPMNNCAT-UHFFFAOYSA-N 0.000 abstract 2
- GOLCXWYRSKYTSP-UHFFFAOYSA-N Arsenious Acid Chemical compound O1[As]2O[As]1O2 GOLCXWYRSKYTSP-UHFFFAOYSA-N 0.000 abstract 2
- -1 aromatic diazo compounds Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- RZXMPPFPUUCRFN-UHFFFAOYSA-N p-toluidine Chemical compound CC1=CC=C(N)C=C1 RZXMPPFPUUCRFN-UHFFFAOYSA-N 0.000 abstract 2
- 229940097322 potassium arsenite Drugs 0.000 abstract 2
- HEQWEGCSZXMIJQ-UHFFFAOYSA-M potassium;oxoarsinite Chemical compound [K+].[O-][As]=O HEQWEGCSZXMIJQ-UHFFFAOYSA-M 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000011734 sodium Substances 0.000 abstract 2
- 229910052708 sodium Inorganic materials 0.000 abstract 2
- RLRUFMQAMUHYAA-UHFFFAOYSA-N (4-bromophenyl)arsonic acid Chemical compound O[As](O)(=O)C1=CC=C(Br)C=C1 RLRUFMQAMUHYAA-UHFFFAOYSA-N 0.000 abstract 1
- GODGOGGXLHQPBK-UHFFFAOYSA-N (4-methylphenyl)arsonic acid Chemical compound CC1=CC=C([As](O)(O)=O)C=C1 GODGOGGXLHQPBK-UHFFFAOYSA-N 0.000 abstract 1
- JZMXTMPPTSCOHL-UHFFFAOYSA-N (5-diazocyclohexa-1,3-dien-1-yl)arsonic acid Chemical compound [N+](=[N-])=C1CC(=CC=C1)[As](O)(O)=O JZMXTMPPTSCOHL-UHFFFAOYSA-N 0.000 abstract 1
- FFVSGYAQHXJFAL-UHFFFAOYSA-N 1-(3,4-diaminophenyl)ethanone Chemical compound CC(=O)C1=CC=C(N)C(N)=C1 FFVSGYAQHXJFAL-UHFFFAOYSA-N 0.000 abstract 1
- LYDVWYSWOJNBMG-UHFFFAOYSA-N 2-(diazomethoxy)phenol Chemical compound [N+](=[N-])=COC=1C(O)=CC=CC1 LYDVWYSWOJNBMG-UHFFFAOYSA-N 0.000 abstract 1
- RANIJPHIVXVUEN-UHFFFAOYSA-N 2-arsonobenzoic acid Chemical compound OC(=O)C1=CC=CC=C1[As](O)(O)=O RANIJPHIVXVUEN-UHFFFAOYSA-N 0.000 abstract 1
- WDFQBORIUYODSI-UHFFFAOYSA-N 4-bromoaniline Chemical compound NC1=CC=C(Br)C=C1 WDFQBORIUYODSI-UHFFFAOYSA-N 0.000 abstract 1
- 229910017253 AsO Inorganic materials 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- AFBPFSWMIHJQDM-UHFFFAOYSA-N N-methyl-N-phenylamine Natural products CNC1=CC=CC=C1 AFBPFSWMIHJQDM-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 229910006069 SO3H Inorganic materials 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- AQLMHYSWFMLWBS-UHFFFAOYSA-N arsenite(1-) Chemical compound O[As](O)[O-] AQLMHYSWFMLWBS-UHFFFAOYSA-N 0.000 abstract 1
- 125000001317 arsoryl group Chemical group *[As](*)(*)=O 0.000 abstract 1
- DMLAVOWQYNRWNQ-UHFFFAOYSA-N azobenzene Chemical compound C1=CC=CC=C1N=NC1=CC=CC=C1 DMLAVOWQYNRWNQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000664 diazo group Chemical group [N-]=[N+]=[*] 0.000 abstract 1
- ZKQIZFHKQOFXBQ-UHFFFAOYSA-L disodium;(4-nitrophenyl)-dioxido-oxo-$l^{5}-arsane Chemical compound [Na+].[Na+].[O-][N+](=O)C1=CC=C([As]([O-])([O-])=O)C=C1 ZKQIZFHKQOFXBQ-UHFFFAOYSA-L 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000007689 inspection Methods 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/74—Aromatic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Abstract
568. Bart, H. Jan. 7, 1910, [Convention date]. Arylarsonic acids.-Aryl substitution derivatives of arsenic acid useful in therapeutics, and having the general formula R - As#O #<OK>OK, u where R is an aromatic radicle and K is a kation, are obtained by causing bodies containing the group - As#<OK>OK or - As = O to react with aromatic diazo compounds, with the exception of normal diazobenzene, in neutral acid, or alkaline solution or suspension, preferably with the application of heat. Suitable compounds containing the afore-mentioned groups are arsenious acid or its salts, arylarsenic oxides, arylarsinious acids, or their salts, &c. In examples p-bromphenylarsonic acid is produced from the diazo compound of p-bromaniline, pmonoacetylaminophenylarsonic acid from the diazo compound of p-monoacetylphenylenediamine, p-tolylarsonic acid from the diazo compound of p-toluidine, and o-carboxyphenylarsonic acid from the diazo compound of oaminobenzoic acid. The Specification as open to inspection under Section 91 (3) (a) mentions also the use of diazo compounds containing more than one aromatic nucleus in which at least a diazo group is present, and also the use of diazo compounds from arylarsinic, or polyarsinic, acids which may also contain substituents such as OH, NH2, and NO2. Compounds of the type <#R>R #AS# <OK>O may also be produced, and in examples compounds are produced from potassium isodiazobenzene and potassium arsenite, sodium o-nitroisodiazobenzene or its isomers and sodium arsenite, 4-nitro-2-diazophenol or its isomers and sodium arsenite, sodium m-diazophenylarsonate or diazoarsonic acids containing substituents such as NH2, OH, halogen, SO3H, AsO.(OH)2, &c. and potassium arsenite, p-nitrodiazobenzene and arsenious acid, 4-nitro-2-diazophenol and magnesium arsenite, p-nitrodiazobenzene and sodium p-nitrophenylarsonate or compounds with positive substituents such as macetylaminophenylarsonic acid, and from pdiazophenol or its isomers, or diazopolyphenols, or ethers or esters of any of these compounds, such as diazoguaiacol, and sodium arsenite. This subject - matter does not appear in the Specification as accepted.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE191100568X | 1910-01-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB191100568A true GB191100568A (en) | 1911-07-27 |
Family
ID=32336945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB191100568D Expired GB191100568A (en) | 1910-01-07 | 1911-01-09 | Improvements in the Manufacture of Organic Derivatives of Arsenic Acid. |
Country Status (2)
| Country | Link |
|---|---|
| DE (3) | DE254345C (en) |
| GB (1) | GB191100568A (en) |
-
0
- DE DENDAT268172D patent/DE268172C/de not_active Expired
- DE DENDAT250264D patent/DE250264C/de not_active Expired
- DE DENDAT254345D patent/DE254345C/de not_active Expired
-
1911
- 1911-01-09 GB GB191100568D patent/GB191100568A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE254345C (en) | 1912-11-30 |
| DE250264C (en) | 1900-01-01 |
| DE268172C (en) | 1913-12-09 |
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