GB1591723A - 1-amino-2-hydroxy-3-heterocyclyloxy-propanes - Google Patents
1-amino-2-hydroxy-3-heterocyclyloxy-propanes Download PDFInfo
- Publication number
- GB1591723A GB1591723A GB39204/77A GB3920477A GB1591723A GB 1591723 A GB1591723 A GB 1591723A GB 39204/77 A GB39204/77 A GB 39204/77A GB 3920477 A GB3920477 A GB 3920477A GB 1591723 A GB1591723 A GB 1591723A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- yloxy
- compound
- propan
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1263576A CH607585A5 (en) | 1976-10-05 | 1976-10-05 | Process for the preparation of 2-[3'-(2-(3,4-dimethoxy-phenyl)ethylamino)-2'-hydroxypropoxy]-3-cyanop yridine |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1591723A true GB1591723A (en) | 1981-06-24 |
Family
ID=4384944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB39204/77A Expired GB1591723A (en) | 1976-10-05 | 1977-09-20 | 1-amino-2-hydroxy-3-heterocyclyloxy-propanes |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5350177A (ko) |
AT (1) | AT358037B (ko) |
AU (1) | AU514676B2 (ko) |
BE (1) | BE858867A (ko) |
CA (1) | CA1105021A (ko) |
CH (1) | CH607585A5 (ko) |
DE (1) | DE2740678A1 (ko) |
DK (1) | DK402877A (ko) |
ES (1) | ES462389A1 (ko) |
FI (1) | FI772681A (ko) |
FR (1) | FR2367065A1 (ko) |
GB (1) | GB1591723A (ko) |
GR (1) | GR71677B (ko) |
IE (1) | IE45692B1 (ko) |
IL (1) | IL53013A (ko) |
NL (1) | NL7710394A (ko) |
NO (1) | NO773125L (ko) |
NZ (1) | NZ185267A (ko) |
PT (1) | PT67048B (ko) |
SE (1) | SE7710250L (ko) |
ZA (1) | ZA775698B (ko) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986006368A1 (en) * | 1985-04-20 | 1986-11-06 | Smith Kline & French Laboratories Limited | Stereoselective process and chiral intermediates for aryloxydropanolamines |
US4894453A (en) * | 1986-06-30 | 1990-01-16 | Toyo Jozo Kabushiki Kaisha | 2-substituted alkoxy-3-substituted-pyrazines |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4208416A (en) * | 1978-06-27 | 1980-06-17 | Merck & Co., Inc. | N-Aralkyl containing cyanopyridines |
US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
DK267779A (da) * | 1978-06-27 | 1979-12-28 | Merck & Co Inc | Fr&mgangsmaade til fremstilling af n-aralkylamino-propoxycyanopyridiner |
AU1580001A (en) * | 1999-11-15 | 2001-05-30 | Eli Lilly And Company | Process for the preparation of aryloxy propanolamines |
-
1976
- 1976-10-05 CH CH1263576A patent/CH607585A5/xx not_active IP Right Cessation
-
1977
- 1977-09-09 DE DE19772740678 patent/DE2740678A1/de not_active Withdrawn
- 1977-09-09 DK DK402877A patent/DK402877A/da unknown
- 1977-09-09 NO NO773125A patent/NO773125L/no unknown
- 1977-09-09 AT AT648777A patent/AT358037B/de not_active IP Right Cessation
- 1977-09-12 FI FI772681A patent/FI772681A/fi not_active Application Discontinuation
- 1977-09-13 SE SE7710250A patent/SE7710250L/xx not_active Application Discontinuation
- 1977-09-15 ES ES462389A patent/ES462389A1/es not_active Expired
- 1977-09-16 FR FR7728037A patent/FR2367065A1/fr active Granted
- 1977-09-19 PT PT67048A patent/PT67048B/pt unknown
- 1977-09-19 JP JP11169877A patent/JPS5350177A/ja active Pending
- 1977-09-20 GB GB39204/77A patent/GB1591723A/en not_active Expired
- 1977-09-20 BE BE181044A patent/BE858867A/xx not_active IP Right Cessation
- 1977-09-22 NL NL7710394A patent/NL7710394A/xx not_active Application Discontinuation
- 1977-09-22 IE IE1938/77A patent/IE45692B1/en unknown
- 1977-09-23 CA CA287,391A patent/CA1105021A/en not_active Expired
- 1977-09-23 ZA ZA00775698A patent/ZA775698B/xx unknown
- 1977-09-26 NZ NZ185267A patent/NZ185267A/xx unknown
- 1977-09-26 AU AU29125/77A patent/AU514676B2/en not_active Expired
- 1977-09-28 IL IL53013A patent/IL53013A/xx unknown
- 1977-09-29 GR GR54455A patent/GR71677B/el unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986006368A1 (en) * | 1985-04-20 | 1986-11-06 | Smith Kline & French Laboratories Limited | Stereoselective process and chiral intermediates for aryloxydropanolamines |
US4894453A (en) * | 1986-06-30 | 1990-01-16 | Toyo Jozo Kabushiki Kaisha | 2-substituted alkoxy-3-substituted-pyrazines |
Also Published As
Publication number | Publication date |
---|---|
FI772681A (fi) | 1978-04-06 |
DE2740678A1 (de) | 1978-04-06 |
SE7710250L (sv) | 1978-04-06 |
JPS5350177A (en) | 1978-05-08 |
NL7710394A (nl) | 1978-04-07 |
NO773125L (no) | 1978-04-06 |
DK402877A (da) | 1978-04-06 |
IE45692B1 (en) | 1982-10-20 |
IL53013A (en) | 1981-09-13 |
BE858867A (fr) | 1978-03-20 |
IE45692L (en) | 1978-04-05 |
IL53013A0 (en) | 1977-11-30 |
AU2912577A (en) | 1979-04-05 |
AT358037B (de) | 1980-08-11 |
NZ185267A (en) | 1979-07-11 |
PT67048B (de) | 1979-02-16 |
CH607585A5 (en) | 1978-09-15 |
ES462389A1 (es) | 1978-07-01 |
AU514676B2 (en) | 1981-02-19 |
FR2367065B1 (ko) | 1980-10-10 |
ZA775698B (en) | 1978-05-30 |
ATA648777A (de) | 1980-01-15 |
CA1105021A (en) | 1981-07-14 |
FR2367065A1 (fr) | 1978-05-05 |
PT67048A (de) | 1977-10-01 |
GR71677B (ko) | 1983-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |