GB1583023A - Blood fractionating apparatus and process - Google Patents
Blood fractionating apparatus and process Download PDFInfo
- Publication number
- GB1583023A GB1583023A GB18483/78A GB1848378A GB1583023A GB 1583023 A GB1583023 A GB 1583023A GB 18483/78 A GB18483/78 A GB 18483/78A GB 1848378 A GB1848378 A GB 1848378A GB 1583023 A GB1583023 A GB 1583023A
- Authority
- GB
- United Kingdom
- Prior art keywords
- blood
- membrane
- outlet
- fraction
- inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000004369 blood Anatomy 0.000 title claims description 242
- 239000008280 blood Substances 0.000 title claims description 242
- 238000000034 method Methods 0.000 title claims description 22
- 239000012528 membrane Substances 0.000 claims description 84
- 230000017531 blood circulation Effects 0.000 claims description 33
- 238000004891 communication Methods 0.000 claims description 14
- 239000012530 fluid Substances 0.000 claims description 14
- 238000009826 distribution Methods 0.000 claims description 9
- 208000007536 Thrombosis Diseases 0.000 claims description 8
- 210000004204 blood vessel Anatomy 0.000 claims description 7
- 230000004075 alteration Effects 0.000 claims description 6
- 238000011065 in-situ storage Methods 0.000 claims description 5
- 239000011148 porous material Substances 0.000 claims description 5
- 238000012986 modification Methods 0.000 claims description 4
- 230000004048 modification Effects 0.000 claims description 4
- 210000002966 serum Anatomy 0.000 claims description 4
- 239000012503 blood component Substances 0.000 claims description 3
- 208000015181 infectious disease Diseases 0.000 claims description 3
- 210000002381 plasma Anatomy 0.000 description 22
- 239000000463 material Substances 0.000 description 9
- 210000003743 erythrocyte Anatomy 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 8
- 239000000706 filtrate Substances 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- 239000003146 anticoagulant agent Substances 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 230000002093 peripheral effect Effects 0.000 description 3
- 229920002379 silicone rubber Polymers 0.000 description 3
- 239000004945 silicone rubber Substances 0.000 description 3
- 210000003462 vein Anatomy 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- -1 polypropylenes Polymers 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 210000005253 yeast cell Anatomy 0.000 description 2
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 229920002319 Poly(methyl acrylate) Polymers 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 239000002473 artificial blood Substances 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
- B01D65/08—Prevention of membrane fouling or of concentration polarisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
- B01D63/087—Single membrane modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/20—By influencing the flow
- B01D2321/2008—By influencing the flow statically
- B01D2321/2016—Static mixers; Turbulence generators
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74359376A | 1976-11-22 | 1976-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1583023A true GB1583023A (en) | 1981-01-21 |
Family
ID=24989380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18483/78A Expired GB1583023A (en) | 1976-11-22 | 1978-05-09 | Blood fractionating apparatus and process |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE2823935C2 (https=) |
| FR (1) | FR2427119A1 (https=) |
| GB (1) | GB1583023A (https=) |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3725445A1 (de) * | 1987-07-31 | 1987-12-03 | Bbc Brown Boveri & Cie | Testzelle fuer membranverfahren |
| WO2001089599A3 (en) * | 2000-05-23 | 2003-01-16 | Chf Solutions Inc | Method and apparatus for peripheral vein fluid removal in heart failure |
| US6796955B2 (en) | 2002-02-14 | 2004-09-28 | Chf Solutions, Inc. | Method to control blood and filtrate flowing through an extracorporeal device |
| US6887214B1 (en) | 2000-09-12 | 2005-05-03 | Chf Solutions, Inc. | Blood pump having a disposable blood passage cartridge with integrated pressure sensors |
| US6923782B2 (en) | 2001-04-13 | 2005-08-02 | Chf Solutions, Inc. | User interface for blood treatment device |
| US6947131B2 (en) | 2002-05-07 | 2005-09-20 | Chf Solutions, Inc. | Blood leak detector for extracorporeal treatment system |
| US7297270B2 (en) | 2003-04-04 | 2007-11-20 | Chf Solutions, Inc. | Hollow fiber filter for extracorporeal blood circuit |
| US7303540B2 (en) | 2004-04-26 | 2007-12-04 | Chf Solutions, Inc. | User interface for blood treatment device |
| US7399289B2 (en) | 2000-11-27 | 2008-07-15 | Chf Solutions, Inc. | Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood |
| US7462161B2 (en) | 2000-11-02 | 2008-12-09 | Chf Solutions, Inc. | Method and apparatus for blood withdrawal and infusion using a pressure controller |
| US7671974B2 (en) | 2003-10-29 | 2010-03-02 | Chf Solutions Inc. | Cuvette apparatus and system for measuring optical properties of a liquid such as blood |
| US8517968B2 (en) | 2011-02-25 | 2013-08-27 | Fresenius Medical Care Holdings, Inc. | Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system |
| US8743354B2 (en) | 2010-09-07 | 2014-06-03 | Fresenius Medical Care Holdings, Inc. | Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system |
| USD725261S1 (en) | 2012-02-24 | 2015-03-24 | Fresenius Medical Care Holdings, Inc. | Blood flow chamber |
| US9173988B2 (en) | 2010-11-17 | 2015-11-03 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
| US9194792B2 (en) | 2010-09-07 | 2015-11-24 | Fresenius Medical Care Holdings, Inc. | Blood chamber for an optical blood monitoring system |
| US9370324B2 (en) | 2008-11-05 | 2016-06-21 | Fresenius Medical Care Holdings, Inc. | Hemodialysis patient data acquisition, management and analysis system |
| USD799031S1 (en) | 2015-09-09 | 2017-10-03 | Fresenius Medical Care Holdings, Inc. | Blood flow chamber with directional arrow |
| US9801993B2 (en) | 2010-11-17 | 2017-10-31 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
| US10155080B2 (en) | 2003-11-05 | 2018-12-18 | Baxter International Inc. | Renal therapy system with cassette-based blood and dialysate pumping |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2527467A1 (fr) * | 1982-05-28 | 1983-12-02 | Rhone Poulenc Sa | Appareil a membranes semi-permeables, utilisable plus particulierement en plasmapherese |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3491021A (en) * | 1967-10-18 | 1970-01-20 | Morgan G Huntington | Method and apparatus for non-cyclic concentration of solution-suspension |
| AT308767B (de) * | 1970-06-08 | 1973-07-25 | Heinrich Frings Maschinen Und | Verfahren und Vorrichtung zur Filtration von Flüssigkeiten, die Mikroorganismen, Makromoleküle oder feinteilige Feststoffe enthalten |
| DE2340139A1 (de) * | 1973-08-08 | 1975-02-27 | Yuasa Battery Co Ltd | Separator |
| CH569505A5 (https=) * | 1973-10-23 | 1975-11-28 | Kaspar Jan | |
| GB1506555A (en) * | 1974-05-24 | 1978-04-05 | Johnson & Johnson | Blood reservoir |
-
1978
- 1978-05-09 GB GB18483/78A patent/GB1583023A/en not_active Expired
- 1978-05-29 DE DE2823935A patent/DE2823935C2/de not_active Expired
- 1978-05-29 FR FR7815956A patent/FR2427119A1/fr active Granted
Cited By (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3725445A1 (de) * | 1987-07-31 | 1987-12-03 | Bbc Brown Boveri & Cie | Testzelle fuer membranverfahren |
| US7935071B2 (en) | 2000-05-23 | 2011-05-03 | Chf Solutions, Inc. | Method and apparatus for peripheral vein fluid removal in heart failure |
| WO2001089599A3 (en) * | 2000-05-23 | 2003-01-16 | Chf Solutions Inc | Method and apparatus for peripheral vein fluid removal in heart failure |
| US9440018B2 (en) | 2000-05-23 | 2016-09-13 | Gambro Lundia Ab | Method for ultrafiltration of blood |
| US6890315B1 (en) | 2000-05-23 | 2005-05-10 | Chf Solutions, Inc. | Method and apparatus for vein fluid removal in heart failure |
| US7311689B2 (en) | 2000-05-23 | 2007-12-25 | Chf Solutions, Inc. | Method and apparatus for peripheral vein fluid removal in heart failure |
| US8603021B2 (en) | 2000-05-23 | 2013-12-10 | Gambro Uf Solutions, Inc. | Method and apparatus for ultrafiltration of blood |
| US6887214B1 (en) | 2000-09-12 | 2005-05-03 | Chf Solutions, Inc. | Blood pump having a disposable blood passage cartridge with integrated pressure sensors |
| US7410473B2 (en) | 2000-09-12 | 2008-08-12 | Chf Solutions Inc. | Blood pump having a disposable blood filter with integrated pressure sensors |
| US7955289B2 (en) | 2000-11-02 | 2011-06-07 | Chf Solutions, Inc. | Method and apparatus for blood withdrawal and infusion using a pressure controller |
| US7674237B2 (en) | 2000-11-02 | 2010-03-09 | Chf Solutions, Inc. | Method and apparatus for blood withdrawal and infusion using a pressure controller |
| US8702638B2 (en) | 2000-11-02 | 2014-04-22 | Gambro Uf Solutions, Inc. | Method for blood withdrawal and infusion using a pressure controller |
| US7462161B2 (en) | 2000-11-02 | 2008-12-09 | Chf Solutions, Inc. | Method and apparatus for blood withdrawal and infusion using a pressure controller |
| US7399289B2 (en) | 2000-11-27 | 2008-07-15 | Chf Solutions, Inc. | Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood |
| US6923782B2 (en) | 2001-04-13 | 2005-08-02 | Chf Solutions, Inc. | User interface for blood treatment device |
| US7647834B2 (en) | 2001-04-13 | 2010-01-19 | Chf Solutions Inc. | Pressure sensor disconnect detection for a blood treatment device |
| US7886611B2 (en) | 2001-04-13 | 2011-02-15 | Chf Solutions Inc. | Pressure sensor disconnect detection for a blood treatment device |
| US6796955B2 (en) | 2002-02-14 | 2004-09-28 | Chf Solutions, Inc. | Method to control blood and filtrate flowing through an extracorporeal device |
| US7540851B2 (en) | 2002-02-14 | 2009-06-02 | Chf Solutions, Inc. | Method to control blood and filtrate flowing through an extracorporeal device |
| US6947131B2 (en) | 2002-05-07 | 2005-09-20 | Chf Solutions, Inc. | Blood leak detector for extracorporeal treatment system |
| US7230687B2 (en) | 2002-05-07 | 2007-06-12 | Chf Solutions Inc. | Blood leak detector for extracorporeal treatment system |
| US7410582B2 (en) | 2003-04-04 | 2008-08-12 | Chf Solutions Inc. | Hollow fiber filter for extracorporeal blood circuit |
| US7297270B2 (en) | 2003-04-04 | 2007-11-20 | Chf Solutions, Inc. | Hollow fiber filter for extracorporeal blood circuit |
| US7671974B2 (en) | 2003-10-29 | 2010-03-02 | Chf Solutions Inc. | Cuvette apparatus and system for measuring optical properties of a liquid such as blood |
| US10155080B2 (en) | 2003-11-05 | 2018-12-18 | Baxter International Inc. | Renal therapy system with cassette-based blood and dialysate pumping |
| US11524103B2 (en) | 2003-11-05 | 2022-12-13 | Baxter International Inc. | Hemodiafiltration system with disposable pumping unit |
| US8197432B2 (en) | 2004-04-26 | 2012-06-12 | Gambro Uf Solutions, Inc. | User interface for blood treatment device |
| US7303540B2 (en) | 2004-04-26 | 2007-12-04 | Chf Solutions, Inc. | User interface for blood treatment device |
| US7585286B2 (en) | 2004-04-26 | 2009-09-08 | Chf Solutions, Inc. | User interface for blood treatment device |
| US12558466B2 (en) | 2006-09-11 | 2026-02-24 | Vantive Us Healthcare Llc | Hemodiafiltration system with disposable pumping unit |
| US9370324B2 (en) | 2008-11-05 | 2016-06-21 | Fresenius Medical Care Holdings, Inc. | Hemodialysis patient data acquisition, management and analysis system |
| US9285305B2 (en) | 2010-09-07 | 2016-03-15 | Fresenius Medical Care Holdings, Inc. | Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system |
| US9194792B2 (en) | 2010-09-07 | 2015-11-24 | Fresenius Medical Care Holdings, Inc. | Blood chamber for an optical blood monitoring system |
| US8743354B2 (en) | 2010-09-07 | 2014-06-03 | Fresenius Medical Care Holdings, Inc. | Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system |
| US11013846B2 (en) | 2010-11-17 | 2021-05-25 | Fresenius Medical Care Holdings, Inc. | Controlling data output of a sensor clip assembly for an optical monitoring system |
| US9173988B2 (en) | 2010-11-17 | 2015-11-03 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
| US10179201B2 (en) | 2010-11-17 | 2019-01-15 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
| US9801993B2 (en) | 2010-11-17 | 2017-10-31 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
| US10471201B2 (en) | 2010-11-17 | 2019-11-12 | Fresenius Medical Care Holdings, Inc. | Sensor clip assembly for an optical monitoring system |
| US10668204B2 (en) | 2010-11-17 | 2020-06-02 | Fresenius Medical Care Holdings, Inc. | Remote interfacing with a sensor clip assembly for an optical monitoring system |
| US8517968B2 (en) | 2011-02-25 | 2013-08-27 | Fresenius Medical Care Holdings, Inc. | Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system |
| USD725261S1 (en) | 2012-02-24 | 2015-03-24 | Fresenius Medical Care Holdings, Inc. | Blood flow chamber |
| USD757934S1 (en) | 2012-02-24 | 2016-05-31 | Fresenius Medical Holdings, Inc. | Blood flow chamber |
| USD799031S1 (en) | 2015-09-09 | 2017-10-03 | Fresenius Medical Care Holdings, Inc. | Blood flow chamber with directional arrow |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2823935C2 (de) | 1984-11-22 |
| FR2427119B1 (https=) | 1983-05-06 |
| DE2823935A1 (de) | 1979-12-13 |
| FR2427119A1 (fr) | 1979-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |