GB1581096A - Phenyl-2-pyridinemethanol compounds and method for their production - Google Patents

Phenyl-2-pyridinemethanol compounds and method for their production Download PDF

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Publication number
GB1581096A
GB1581096A GB6493/78A GB649378A GB1581096A GB 1581096 A GB1581096 A GB 1581096A GB 6493/78 A GB6493/78 A GB 6493/78A GB 649378 A GB649378 A GB 649378A GB 1581096 A GB1581096 A GB 1581096A
Authority
GB
United Kingdom
Prior art keywords
cis
dimethyl
compound
acid
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6493/78A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/772,203 external-priority patent/US4112103A/en
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Publication of GB1581096A publication Critical patent/GB1581096A/en
Priority to SG60383A priority Critical patent/SG60383G/en
Priority to HK4084A priority patent/HK4084A/xx
Priority to MY8500011A priority patent/MY8500011A/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB6493/78A 1977-02-25 1978-02-17 Phenyl-2-pyridinemethanol compounds and method for their production Expired GB1581096A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SG60383A SG60383G (en) 1978-02-17 1983-09-26 Alpha-phenyl-2-pyridinemethanol compounds and method for their production
HK4084A HK4084A (en) 1978-02-17 1984-01-12 Alfa-phenyl-2-pyridinemethanol compounds and method for their production
MY8500011A MY8500011A (en) 1978-02-17 1985-12-30 (alpha)-phenyl-2-pyridinemethanol compounds and method for their production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/772,203 US4112103A (en) 1976-04-15 1977-02-25 Antiarrhythmic (+,-)-cis-α-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanols

Publications (1)

Publication Number Publication Date
GB1581096A true GB1581096A (en) 1980-12-10

Family

ID=25094280

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6493/78A Expired GB1581096A (en) 1977-02-25 1978-02-17 Phenyl-2-pyridinemethanol compounds and method for their production

Country Status (11)

Country Link
JP (1) JPS53105479A (enrdf_load_html_response)
AT (1) AT358040B (enrdf_load_html_response)
BE (1) BE864033A (enrdf_load_html_response)
CA (1) CA1096382A (enrdf_load_html_response)
CH (1) CH635095A5 (enrdf_load_html_response)
DE (1) DE2806654A1 (enrdf_load_html_response)
DK (1) DK143229C (enrdf_load_html_response)
ES (1) ES467100A1 (enrdf_load_html_response)
FR (1) FR2381761A1 (enrdf_load_html_response)
GB (1) GB1581096A (enrdf_load_html_response)
PH (1) PH13125A (enrdf_load_html_response)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116514770A (zh) * 2023-05-09 2023-08-01 郑州大学 2-苄基吡啶高效制备吡美诺的方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818914B2 (ja) * 1991-04-05 1998-10-30 シャープ株式会社 多目的スチーム発生器

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757408A (fr) * 1969-10-13 1971-04-13 Thomae Gmbh Dr K Nouveaux butanols tertiaires a constituants basiques

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116514770A (zh) * 2023-05-09 2023-08-01 郑州大学 2-苄基吡啶高效制备吡美诺的方法
CN116514770B (zh) * 2023-05-09 2025-02-07 郑州大学 2-苄基吡啶高效制备吡美诺的方法

Also Published As

Publication number Publication date
ES467100A1 (es) 1978-11-01
FR2381761A1 (fr) 1978-09-22
FR2381761B1 (enrdf_load_html_response) 1982-03-26
DK143229B (da) 1981-07-27
CH635095A5 (en) 1983-03-15
AT358040B (de) 1980-08-11
ATA117078A (de) 1980-01-15
CA1096382A (en) 1981-02-24
DE2806654A1 (de) 1978-08-31
DE2806654C2 (enrdf_load_html_response) 1987-07-16
DK143229C (da) 1981-11-30
JPS6257632B2 (enrdf_load_html_response) 1987-12-02
PH13125A (en) 1979-12-12
JPS53105479A (en) 1978-09-13
DK73278A (da) 1978-08-26
BE864033A (fr) 1978-06-16

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Legal Events

Date Code Title Description
PS Patent sealed
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950217