GB1559874A - Device for diffusing substances between two fluids - Google Patents
Device for diffusing substances between two fluids Download PDFInfo
- Publication number
- GB1559874A GB1559874A GB32529/76A GB3252976A GB1559874A GB 1559874 A GB1559874 A GB 1559874A GB 32529/76 A GB32529/76 A GB 32529/76A GB 3252976 A GB3252976 A GB 3252976A GB 1559874 A GB1559874 A GB 1559874A
- Authority
- GB
- United Kingdom
- Prior art keywords
- casing
- chamber
- fluid
- tubes
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000012530 fluid Substances 0.000 title claims description 46
- 239000000126 substance Substances 0.000 title claims description 9
- 239000008280 blood Substances 0.000 claims description 14
- 210000004369 blood Anatomy 0.000 claims description 14
- 239000012528 membrane Substances 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 10
- 210000003734 kidney Anatomy 0.000 claims description 5
- 238000004026 adhesive bonding Methods 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 2
- 239000007789 gas Substances 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 241000883488 Mammillaria karwinskiana Species 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 239000008246 gaseous mixture Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/04—Hollow fibre modules comprising multiple hollow fibre assemblies
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Description
(54) A DEVICE FOR DIFFUSING SUBSTANCES
BETWEEN TWO FLUIDS
(71) We, EXTRACORPOREAL MEDICAL SPECIALTIES INC, of Royal
Cross Roads, King of Prussia, Pennsylvania
19406, United States of America, a
Corporation of the State of Pennsylvania,
United States of America, do hereby declare the invention for which we pray that a patent may be granted to us, and the method by which it is to be performed, to be particularly described in and by the following statement:- The present invention relates to a device for diffusing substances between two fluids via semi-permeable membranes having the shape of thin-walled tubes through which one of the said fluids is caused to flow, while the said tubes are surrounded on the outside by the other one of the said fluids, collecting inlets and collecting outlets being provided for the respective fluids.
According to a first aspect of the present invention, there is provided a device for diffusing substances between two fluids, said device comprising at least two parallel chambers each having at least one semipermeable membrane in the form of a thinwalled tube extending longitudinally therethrough; inlet means and outlet means connected to said tubes at respective ends of the chambers for passing a first fluid in simultaneous concurrent flow through all of said tubes; respective inlets and outlets to each chamber for passing a second fluid in countercurrent flow to said first fluid; and conduit means connecting the outlet of each chamber except one to the inlet of another chamber whereby the second fluid is caused to flow sequentially through the chambers, said conduit means not containing semipermeable tubes connected to said inlet and outlet means for the first fluid and preferably not containing any semipermeable membrane.
It is preferred that the chambers are provided within a tubular casing and further that the conduit means comprises passages provided in said casing. Advantageously, the casing is divided into said chambers by longitudinally extending intermediate walls.
in which case the said passages conveniently can be formed between respective pairs of intermediate walls of adjacent chambers connected by the passage.
According to a second aspect of the present invention, there is provided a device for diffusing substances between two fluids, said device comprising a tubular casing divided by longitudinally extending intermediate walls into at least two longitudinal chambers and into a respective longitudinal passage connecting each pair of adjacent chambers, which passage connects one end of one chamber of said pair to the opposite end of the other chamber of the pair whereby a fluid can be passed sequentially through the chambers; at least one respective semi-permeable membrane in the form of a thin-walled tube extending longitudinally through each chamber; inlet means and outlet means connected to said tubes for passing a first fluid through the tubes; and a respective inlet and outlet to the tubular casing for passing a second fluid sequentially through the said chambers; and wherein the said respective passage does not contain semi-permeable tubes connected to said inlet and outlet means for the first fluid and preferably does not contain any semipermeable membranes. It is preferred that the respective passage is located between the respective pair of adjacent chambers.
The following will refer to both aspects of the present invention but it will be appreciated that references to a tubular casing apply as far as the first aspect of the invention is concerned to the preferred embodiment comprising such a casing.
Preferably, each chamber has a plurality of the thin-walled tubes extending longitudinally therethrough and said tubes are hollow fibres having a preferred outer diameter of 0.3 to 0.5 mm.
Conveniently, the intermediate wall separating the respective passage from one of its pair of adjacent chambers extends from one end of the tubular casing to terminate short of the opposite end of the casing and the intermediate wall separating the passage from the other of its pair of adjacent chambers extends from said opposite end of the casing to terminate short of the said one end of the casing. In this manner the inlets and outlets for conveying the second fluid between the chambers can be readily provided.
The tubular casing suitably is of generally rectangular cross-section and the intermediate walls extend in plane-parallel relationship to an opposed pair of side walls of the casing. The casing can be formed of two longitudinal parts connected together and in this case it is preferred that one of the parts carries the intermediate walls and sealing means are provided to seal said walls against the other of said parts. The sealing means can be integral with the said other part of the casing.
Preferably, the inlet means and outlet means for the first fluid include an inlet chamber and an outlet chamber respectively into which all of the thin-walled tubes open at their respective ends.
The casing advantageously terminates at its ends in respective end walls through which the thin-walled tubes pass and the said inlet and outlet chambers are defined
by respective end caps having an inlet and
outlet respectively for the first fluid. An
inlet and outlet for the second fluid preferably is provided in the side of the
casing between said end walls to efficiently seal the fluids from each other.
The device of the invention is primarily
intended for use in purifying blood, i.e. as a
so-called artificial kidney, in which case
blood flows through the thin-walled tubes
while a purifying liquid is caused to flow
outside the tubes. The said purifying liquid
normally consists of pure water to which
certain salts have been added. The
invention will be described hereinafter with
particular reference to purifying blood. It
will readily be appreciated however that the
device may also be used for many other
purposes. It may for example be used to
oxygenize blood, in which case the said.
purifying liquid is replaced by oxygen or a
gaseous mixture containing oxygen.
Alternatively, the device may be used for
transferring substances from one gas to
another gas. In this connection, the term
"fluid" is used in this Specification
(including the Claims) to mean a gas or
liquid.
The following is a description by way of
example only and with reference to the
accompanying drawings ~ of a presently
preferred embodiment of the invention. In
the drawings: Figure 1 is a longitudinal section of an
artificial kidney in accordance with one
preferred embodiment of the invention:
Figure 2 is a side view, partly in section, corresponding to Figure 1;
Figure 3 is a view, partly in section, taken at right angles and from the left of the view of Figure 2; and
Figure 4 is a section on line VI-VI of
Figure 2;
Referring to Figures 1 to 4, an artificial kidney consists of an outer casing 1 which is composed of two parts la and lb (see Figure 4). The two parts are held together in the example shown by hook-shaped locking members 2a and 2b but in practice may be held together in any arbitrary way, for instance by gluing, welding or by some kind of screw or clamping means. The part lb carried intermediate walls 3b forming between them chambers 4 and passages 5, respectively. Through the chambers 4 there pass semi-permeable membranes in the form of thin-walled tubes 6 running from one end wall 7 to another end wall 7 (see
Figure 1). The channels 5 lack such thinwalled tubes. The intermediate walls 3b are sealed against the part la of the outer casing by seals 8a, which seals may be integral with the part la or may be separate therefrom. It should be observed that the thin-walled tubes 6 are shown in the drawings with exaggerated thickness for the sake of clarity. In practice, the tube outer diameter is preferably 0.3 to 0.5 mm and the wall thickness is extremely small. Such tubes are known for use in dialysis devices and are generally referred to as hollow fibres.
Blood to be purified is supplied in the direction of arrow A via the inlet 9 to an inlet chamber 10. The said chamber 10 is defined on one side by the adjacent end wall 7 and on the other side by an end cap 11.
The thin-walled tubes 6 open without exception into the chamber 10. At their other ends, the tubes 6 open in a corresponding manner into an outlet chamber 12 for the purified blood. From the said chamber 12, the blood is led in the direction of arrow B through an outlet 13.
The outlet chamber 12 is located between the adjacent end wall 7 and an end cap-14.
The device according to the invention is meant to be mounted in the vertical sense, in which case the blood is introduced at the lower end of the device and is discharged from the upper end of the device. A salt solution, or purifying liquid, is however introduced at the upper end of the device in the direction of arrow C via an inlet 15 and flows through a first chamber 4 in the direction of arrow D against the direction of flow of the blood, which direction of blood flow is shown by arrow E. At the lower end of the device, the purifying liquid turns and flows upwardly through an intermediate passage 5. It then flows through a second chamber 4 in the direction of arrow L against the direction of flow of the blood.
After the purifying liquid bas been passed through all of the chamber 4 in the direction of arrow D in countercurrent flow to the blood, it passes through an outlet 16 in the direction of arrow F.
The end walls 7 are formed from a more or less resilient compound tightly enclosing the respective tube openings and thereby effectively sealing the two fluids from one another. Between the end walls 7 and the end caps 11 and 14, respectively, there are mounted gaskets 17 and said end caps 11 and 14 are attached to the outer casing 1 in any arbitrary manner, e.g. by gluing or by some kind of screw or clamping means. In
Figure 3 they are, however, shown attached to the casing 1 by means of hook-shaped locking members 18 and 19.
It will be appreciated that the invention is not limited to the particular details described above but may be varied within the scope of the following Claims. Thus, the shape of the components may vary substantially without departing from said scope of the invention. In particular, the flow shown in the Figures may be reversed so that blood is introduced from above, while the purifying liquid is introduced from below i.e. in directions opposite to those shown by arrows A to F.
WHAT WE CLAIM IS:
1. A device for diffusing substances between two fluids, said device comprising
at least two parallel chambers each having at least one semi-permeable membrane in the form of a thin-walled tube extending longitudinally therethrough;
inlet means and outlet means connected to said tubes at respective ends of the chambers for passing a first fluid in simultaneous concurrent flow through all of said tubes;
respective inlets and outlets to each chamber for passing a second fluid in countercurrent flow to said first fluid; and
conduit means connecting the outlet of each chamber except one to the inlet of another chamber whereby the second fluid is caused to flow sequentially through the chambers, said conduit means not containing semi-permeable tubes connected to said inlet and outlet means for the first fluid.
2. A device as claimed in Claim 1 wherein the said conduit means does not contain any semi-permeable membranes.
3. A device as claimed in Claim 1 or
Claim 2 wherein each chamber has plurality of the thin-walled tubes extending longitudinally therethrough.
4. A device as claimed in Claim 3 wherein the said tubes are hollow fibres.
5. A device as claimed in Claim 4 wherein
the follow fibres have an outer diameter of
0.3 to 0.5 mm.
6. A device as claimed in any one of the
preceding Claims wherein the chambers
are provided within a tubular casing.
7. A device as claimed in Claim 6 wherein
the conduit means comprises passages
provided in the tubular casing.
8. A device as claimed in Claim 6 or
Claim 7 wherein the tubular casing is
divided into said chamber by longitudinally
extending intermediate walls.
9. A device as claimed in Claim 8 wherein
the conduit means comprises passages
formed between respective pairs of
intermediate walls of adjacent chambers
connected by the passage.
10. A device as claimed in Claim 9
wherein one of the said pair of intermediate
walls forming the respective passage
extends from one end of the tubular casing
to terminate short of the opposite end of the
casing and the other of the said pair of
intermediate walls extends from said
opposite end of the casing to terminate
short of the said one end of the casing.
11. A device as claimed in any one of
Claims 8 to 10 wherein the tubular casing
has a generally rectangular cross-section
and the intermediate walls extend in plane
parallel relationship to an opposed pair of
side walls of the casing.
12. A device as claimed in any one of the preceding Claims wherein said inlet means and outlet means include an inlet chamber and an outlet chamber respectively into which all of the thin-walled tubes open at their respective ends.
13. A device as claimed in Claim 12 when appendant to any one of Claims 8 to 11 wherein the tubular casing terminates at its ends in respective end walls through which the thin-walled tubes pass and the said inlet chamber and outlet chamber are defined by respective end caps having an inlet and outlet respectively for the first fluid.
14. A device as claimed in Claim 13 wherein the tubular casing has an inlet and outlet for the second fluid in the side of the casing between the said end walls.
15. A device as claimed in any one of
Claims 8 to 11, 12 and 13 wherein the tubular casing is formed of two longitudinal parts connected together.
16. A device as claimed in Claim 15 wherein one of said parts carries the intermediate walls and sealing means are provided to seal said walls against the other of said parts.
17. A device as claimed in Claim 16 wherein said sealing means is integral with said other part.
18. A device substantially as hereinbefore
**WARNING** end of DESC field may overlap start of CLMS **.
Claims (32)
1. A device for diffusing substances between two fluids, said device comprising
at least two parallel chambers each having at least one semi-permeable membrane in the form of a thin-walled tube extending longitudinally therethrough;
inlet means and outlet means connected to said tubes at respective ends of the chambers for passing a first fluid in simultaneous concurrent flow through all of said tubes;
respective inlets and outlets to each chamber for passing a second fluid in countercurrent flow to said first fluid; and
conduit means connecting the outlet of each chamber except one to the inlet of another chamber whereby the second fluid is caused to flow sequentially through the chambers, said conduit means not containing semi-permeable tubes connected to said inlet and outlet means for the first fluid.
2. A device as claimed in Claim 1 wherein the said conduit means does not contain any semi-permeable membranes.
3. A device as claimed in Claim 1 or
Claim 2 wherein each chamber has plurality of the thin-walled tubes extending longitudinally therethrough.
4. A device as claimed in Claim 3 wherein the said tubes are hollow fibres.
5. A device as claimed in Claim 4 wherein
the follow fibres have an outer diameter of
0.3 to 0.5 mm.
6. A device as claimed in any one of the
preceding Claims wherein the chambers
are provided within a tubular casing.
7. A device as claimed in Claim 6 wherein
the conduit means comprises passages
provided in the tubular casing.
8. A device as claimed in Claim 6 or
Claim 7 wherein the tubular casing is
divided into said chamber by longitudinally
extending intermediate walls.
9. A device as claimed in Claim 8 wherein
the conduit means comprises passages
formed between respective pairs of
intermediate walls of adjacent chambers
connected by the passage.
10. A device as claimed in Claim 9
wherein one of the said pair of intermediate
walls forming the respective passage
extends from one end of the tubular casing
to terminate short of the opposite end of the
casing and the other of the said pair of
intermediate walls extends from said
opposite end of the casing to terminate
short of the said one end of the casing.
11. A device as claimed in any one of
Claims 8 to 10 wherein the tubular casing
has a generally rectangular cross-section
and the intermediate walls extend in plane
parallel relationship to an opposed pair of
side walls of the casing.
12. A device as claimed in any one of the preceding Claims wherein said inlet means and outlet means include an inlet chamber and an outlet chamber respectively into which all of the thin-walled tubes open at their respective ends.
13. A device as claimed in Claim 12 when appendant to any one of Claims 8 to 11 wherein the tubular casing terminates at its ends in respective end walls through which the thin-walled tubes pass and the said inlet chamber and outlet chamber are defined by respective end caps having an inlet and outlet respectively for the first fluid.
14. A device as claimed in Claim 13 wherein the tubular casing has an inlet and outlet for the second fluid in the side of the casing between the said end walls.
15. A device as claimed in any one of
Claims 8 to 11, 12 and 13 wherein the tubular casing is formed of two longitudinal parts connected together.
16. A device as claimed in Claim 15 wherein one of said parts carries the intermediate walls and sealing means are provided to seal said walls against the other of said parts.
17. A device as claimed in Claim 16 wherein said sealing means is integral with said other part.
18. A device substantially as hereinbefore
described with reference to and as shown in
Figures 1 to 4 of the accompanying drawings.
19. An artificial kidney as claimed in any one of the preceding Claims.
20. A device for diffusing substances between two fluids, said device comprising
a tubular casing divided by longitudinally extending intermediate walls into at least two longitudinal chambers and into a respective longitudinal passage connecting each pair of adjacent chambers, which passage connects one end of one chamber of said pair to the opposite end of the other chamber of the pair whereby a fluid can be passed sequentially through the chambers;
at least one respective semi-permeable membrane in the form of a thin-walled tube extending longitudinally through each chamber;
inlet means and outlet means connected to said tubes for passing a first fluid through the tubes; and
a respective inlet and outlet to the tubular casing for passing a second fluid sequentially through the said chambers;
and wherein the said respective passage does not ~ contain semi-permeable tubes connected to said inlet and outlet means for the first fluid.
21. A device as claimed in Claim 20 wherein the respective passage does not contain any semi-permeable membranes.
22. A device as claimed in Claim 20 or
Claim 21 wherein each chamber has a plurality of the thin-walled tubes extending longitudinally therethrough.
23. A device as claimed in Claim 22 wherein the said tubes are hollow fibres.
24. A device as claimed in Claim 23 wherein the hollow fibres have an outer diameter of 0.3 to 0.5 mm.
25. A device as claimed in any one of
Claims 20 to 24 wherein the respective passage is located between the respective pair of adjacent chambers.
26. A device as claimed in any one of
Claims 20 to 25 wherein the tubular casing has a generally rectangular cross-section and the intermediate walls extend in plane parallel relationship to an opposed pair of side walls of the casing.
27. A device as claimed in any one of
Claims 20 to 26 wherein the intermediate wall separating the respective passage from one of its pair of adjacent chambers extends from one end of the tubular casing to terminate short of the opposite end of the casing and the intermediate wall separating the passage from the other of its pair of adjacent chambers extends from said opposite end of the casing to terminate short of the said one end of the casing.
28. A device as claimed in any one ol
Claims 20 to 27 wherein the tubular casing is formed of two longitudinal parts connected together.
29. A device as claimed in Claim 28 wherein one of said parts carries the intermediate walls and sealing means are provided to seal said walls against the other of said parts.
30. A device as claimed in Claim 29 wherein said sealing means is integral with said other part.
31. A device as claimed in Claim 20 wherein the tubular casing and intermediate walls are substantially as described hereinbefore with reference to the accompanying drawings.
32. An artificial kidney as claimed in any one of Claims 20 to 31.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7510099A SE393535B (en) | 1975-09-11 | 1975-09-11 | DEVICE FOR DIFFUSION OF THE SUBJECT BETWEEN TWO FLUIDES VIA SEMIPERMEABLE MEMBRANE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1559874A true GB1559874A (en) | 1980-01-30 |
Family
ID=20325510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32529/76A Expired GB1559874A (en) | 1975-09-11 | 1976-08-04 | Device for diffusing substances between two fluids |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5233888A (en) |
| AU (1) | AU499863B2 (en) |
| BE (1) | BE845710A (en) |
| BR (1) | BR7605754A (en) |
| CH (1) | CH597869A5 (en) |
| DE (2) | DE2632044C3 (en) |
| DK (1) | DK347976A (en) |
| FI (1) | FI63859C (en) |
| FR (1) | FR2323427A1 (en) |
| GB (1) | GB1559874A (en) |
| IT (1) | IT1062124B (en) |
| NL (1) | NL171228C (en) |
| NO (1) | NO140285C (en) |
| SE (1) | SE393535B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0028246A1 (en) * | 1979-05-04 | 1981-05-13 | Regents Of The University Of Minnesota | Controlled protein fractionation |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7611942L (en) * | 1975-11-05 | 1977-05-06 | Extracorporeal Med Spec | DIALYZER WITH IHALIGA FIBERS |
| SE422000B (en) * | 1977-10-17 | 1982-02-15 | Gambro Dialysatoren | DEVICE FOR DIFFUSION AND / OR FILTRATION OF THE SUBSTANCE BETWEEN TWO FLUIDS THROUGH SEMIPERMEABLE MEMBRANE, WHICH DEVICE INCLUDES A STACK OF CAMERA IMAGE FRAMES CONTAINING THE SENSOR |
| SE421998B (en) * | 1977-10-17 | 1982-02-15 | Gambro Dialysatoren | DEVICE FOR DIFFUSION AND / OR FILTRATION OF THE SUBSTANCE BETWEEN TWO FLUIDS THROUGH THE SEMIPERMIABLA MEMBRANE, WHICH DEVICE INCLUDES A STACK OF CAMERA IMAGE FRAMES TO CONTINUE THE UNIFORM END PIECES |
| DE2907319A1 (en) * | 1979-02-24 | 1980-09-18 | Bayer Ag | MODULE BLOCK FOR OSMOTIC SEPARATION METHODS |
| JPS5886172A (en) * | 1981-11-18 | 1983-05-23 | テルモ株式会社 | Medical substance moving apparatus |
| DE8136374U1 (en) * | 1981-12-14 | 1988-05-11 | Akzo Gmbh, 5600 Wuppertal | Dialysis device for dialysing fluid |
| JPS61167907U (en) * | 1985-04-05 | 1986-10-18 | ||
| DE3733542A1 (en) * | 1986-10-13 | 1988-07-14 | Akzo Gmbh | Mass transfer appliance |
| DE3809557A1 (en) * | 1988-03-22 | 1989-10-12 | Akzo Gmbh | FABRIC AND / OR HEAT EXCHANGER |
| DE69113436T2 (en) * | 1991-01-30 | 1996-03-07 | Erma Cr. Inc., Kawaguchi, Saitama | Hydroponic system. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3728256A (en) * | 1971-06-22 | 1973-04-17 | Abcor Inc | Crossflow capillary dialyzer |
| FR2231421B1 (en) * | 1973-05-30 | 1976-05-07 | Rhone Poulenc Ind | |
| US3884808A (en) * | 1973-06-20 | 1975-05-20 | Res Dev Systems Inc | Wearable, self-regenerating dialysis appliance |
| JPS50131395A (en) * | 1974-04-04 | 1975-10-17 | ||
| SE7611942L (en) * | 1975-11-05 | 1977-05-06 | Extracorporeal Med Spec | DIALYZER WITH IHALIGA FIBERS |
-
1975
- 1975-09-11 SE SE7510099A patent/SE393535B/en unknown
-
1976
- 1976-07-16 IT IT25395/76A patent/IT1062124B/en active
- 1976-07-16 DE DE2632044A patent/DE2632044C3/en not_active Expired
- 1976-07-16 DE DE19767622505U patent/DE7622505U1/en not_active Expired
- 1976-07-23 AU AU16189/76A patent/AU499863B2/en not_active Expired
- 1976-07-30 FI FI762184A patent/FI63859C/en not_active IP Right Cessation
- 1976-08-02 DK DK347976A patent/DK347976A/en not_active Application Discontinuation
- 1976-08-04 GB GB32529/76A patent/GB1559874A/en not_active Expired
- 1976-08-06 NL NLAANVRAGE7608786,A patent/NL171228C/en not_active IP Right Cessation
- 1976-08-27 FR FR7625930A patent/FR2323427A1/en active Granted
- 1976-08-31 BR BR7605754A patent/BR7605754A/en unknown
- 1976-08-31 BE BE170240A patent/BE845710A/en not_active IP Right Cessation
- 1976-09-02 CH CH1116076A patent/CH597869A5/xx not_active IP Right Cessation
- 1976-09-06 JP JP51106603A patent/JPS5233888A/en active Granted
- 1976-09-10 NO NO763127A patent/NO140285C/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0028246A1 (en) * | 1979-05-04 | 1981-05-13 | Regents Of The University Of Minnesota | Controlled protein fractionation |
| EP0028246A4 (en) * | 1979-05-04 | 1982-03-29 | Univ Minnesota | Controlled protein fractionation. |
Also Published As
| Publication number | Publication date |
|---|---|
| NO763127L (en) | 1977-03-14 |
| BE845710A (en) | 1976-12-16 |
| DK347976A (en) | 1977-03-12 |
| FR2323427A1 (en) | 1977-04-08 |
| AU499863B2 (en) | 1979-05-03 |
| NL171228C (en) | 1983-03-01 |
| FR2323427B1 (en) | 1982-10-01 |
| CH597869A5 (en) | 1978-04-14 |
| DE7622505U1 (en) | 1979-09-13 |
| FI762184A (en) | 1977-03-12 |
| NL171228B (en) | 1982-10-01 |
| JPS5624564B2 (en) | 1981-06-06 |
| DE2632044A1 (en) | 1977-03-24 |
| NL7608786A (en) | 1977-03-15 |
| NO140285B (en) | 1979-04-30 |
| DE2632044C3 (en) | 1980-10-02 |
| SE393535B (en) | 1977-05-16 |
| BR7605754A (en) | 1977-08-23 |
| FI63859B (en) | 1983-05-31 |
| IT1062124B (en) | 1983-06-25 |
| JPS5233888A (en) | 1977-03-15 |
| FI63859C (en) | 1983-09-12 |
| AU1618976A (en) | 1978-01-26 |
| NO140285C (en) | 1979-08-08 |
| DE2632044B2 (en) | 1980-02-07 |
| SE7510099L (en) | 1977-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |