GB1549829A - 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines - Google Patents

10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines

Info

Publication number
GB1549829A
GB1549829A GB21801/76A GB2180176A GB1549829A GB 1549829 A GB1549829 A GB 1549829A GB 21801/76 A GB21801/76 A GB 21801/76A GB 2180176 A GB2180176 A GB 2180176A GB 1549829 A GB1549829 A GB 1549829A
Authority
GB
United Kingdom
Prior art keywords
dimethylergoline
pyrazines
thio
methoxy
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21801/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Priority to GB21801/76A priority Critical patent/GB1549829A/en
Priority to FR7715719A priority patent/FR2352815A1/fr
Priority to US05/799,167 priority patent/US4123613A/en
Priority to CH640177A priority patent/CH630918A5/de
Priority to DE19772723468 priority patent/DE2723468A1/de
Priority to JP6038377A priority patent/JPS52144698A/ja
Publication of GB1549829A publication Critical patent/GB1549829A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB21801/76A 1976-05-26 1976-05-26 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines Expired GB1549829A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB21801/76A GB1549829A (en) 1976-05-26 1976-05-26 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
FR7715719A FR2352815A1 (fr) 1976-05-26 1977-05-23 Derives de pyrazine utilisables comme inhibiteurs de l'agregation des plaquettes
US05/799,167 US4123613A (en) 1976-05-26 1977-05-23 Substituted pyrazines as inhibitors of platelet aggregation
CH640177A CH630918A5 (de) 1976-05-26 1977-05-24 Verfahren zur herstellung von neuen pyrazinderivaten.
DE19772723468 DE2723468A1 (de) 1976-05-26 1977-05-24 Neue pyrazinderivate und verfahren zu deren herstellung
JP6038377A JPS52144698A (en) 1976-05-26 1977-05-24 Novel substituted pyradine derivatives process for preparing same and pharmaceutical composition having platelet coagulation preventing effect containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB21801/76A GB1549829A (en) 1976-05-26 1976-05-26 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines

Publications (1)

Publication Number Publication Date
GB1549829A true GB1549829A (en) 1979-08-08

Family

ID=10169044

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21801/76A Expired GB1549829A (en) 1976-05-26 1976-05-26 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines

Country Status (6)

Country Link
US (1) US4123613A (enExample)
JP (1) JPS52144698A (enExample)
CH (1) CH630918A5 (enExample)
DE (1) DE2723468A1 (enExample)
FR (1) FR2352815A1 (enExample)
GB (1) GB1549829A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653333A5 (de) * 1981-11-04 1985-12-31 Sandoz Ag N-substituierte ergolin- und 9,10-didehydroergolinderivate, ihre herstellung und sie enthaltende arzneimittel.
DE3705060C1 (de) * 1987-02-18 1988-03-03 Alfmeier Walter Gmbh & Co Unterdruckverteilerdose
KR0138005B1 (ko) * 1993-10-21 1998-05-15 김낙두 신규의 화학적 보호제(chemopreventive agent)및 그의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238211A (en) * 1966-03-01 Derhvatives of g-methyl and i,g-dimethyl ergolhne
US3996228A (en) * 1973-12-21 1976-12-07 Societa' Farmaceutici Italia S.P.A. Pyrimidinoaminoethyl ergoline derivatives
US4004011A (en) * 1974-04-16 1977-01-18 Sandoz Ltd. 3-Pyridylamine substituted ergolines
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines

Also Published As

Publication number Publication date
JPS52144698A (en) 1977-12-02
US4123613A (en) 1978-10-31
DE2723468A1 (de) 1977-12-15
FR2352815A1 (fr) 1977-12-23
CH630918A5 (de) 1982-07-15
FR2352815B1 (enExample) 1980-06-27

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee