GB1544404A - Process for preparing esters of 7-amino-cephalosporanic acid derivatives - Google Patents

Process for preparing esters of 7-amino-cephalosporanic acid derivatives

Info

Publication number
GB1544404A
GB1544404A GB7546/75A GB754675A GB1544404A GB 1544404 A GB1544404 A GB 1544404A GB 7546/75 A GB7546/75 A GB 7546/75A GB 754675 A GB754675 A GB 754675A GB 1544404 A GB1544404 A GB 1544404A
Authority
GB
United Kingdom
Prior art keywords
amino
acid derivatives
cephalosporanic acid
preparing esters
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7546/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB7546/75A priority Critical patent/GB1544404A/en
Priority to IE100/76A priority patent/IE42404B1/en
Priority to ZA441A priority patent/ZA76441B/en
Priority to CA244,626A priority patent/CA1071621A/en
Priority to AR262151A priority patent/AR212809A1/en
Priority to FI760292A priority patent/FI760292A/fi
Priority to JP51012737A priority patent/JPS51101995A/ja
Priority to ES445009A priority patent/ES445009A1/en
Priority to DE19762605159 priority patent/DE2605159A1/en
Priority to SE7601534A priority patent/SE7601534L/en
Priority to FR7603744A priority patent/FR2301527A1/en
Priority to BE164288A priority patent/BE838514A/en
Priority to AT118476A priority patent/AT345456B/en
Priority to NL7601662A priority patent/NL7601662A/en
Priority to DK72976*#A priority patent/DK72976A/en
Priority to CH211176A priority patent/CH619957A5/en
Priority to NO760577A priority patent/NO760577L/no
Priority to AU11339/76A priority patent/AU505037B2/en
Priority to US05/826,371 priority patent/US4115646A/en
Publication of GB1544404A publication Critical patent/GB1544404A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

The use of an iodolactone as esterifying agent in the preparation of lactonyl esters of cephalosporins has the consequence that the tendency of double bonds to migrate during the esterification reaction is markedly reduced.
GB7546/75A 1975-02-22 1975-02-22 Process for preparing esters of 7-amino-cephalosporanic acid derivatives Expired GB1544404A (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
GB7546/75A GB1544404A (en) 1975-02-22 1975-02-22 Process for preparing esters of 7-amino-cephalosporanic acid derivatives
IE100/76A IE42404B1 (en) 1975-02-22 1976-01-19 Process for preparing esters of 7-aminocephalosporanic acid derivatives
ZA441A ZA76441B (en) 1975-02-22 1976-01-26 Process for preparing 7-aminocephalosporanic acid derivatives
CA244,626A CA1071621A (en) 1975-02-22 1976-01-30 Process for preparing 7-aminocephalosporanic acid derivatives
AR262151A AR212809A1 (en) 1975-02-22 1976-02-04 PROCEDURE TO PREPARE PHTHALIDYL, CEPHALOSPORIN, AND THEIR DERIVATIVES ESTERS
FI760292A FI760292A (en) 1975-02-22 1976-02-06
JP51012737A JPS51101995A (en) 1975-02-22 1976-02-07
ES445009A ES445009A1 (en) 1975-02-22 1976-02-09 Process for preparing esters of 7-amino-cephalosporanic acid derivatives
DE19762605159 DE2605159A1 (en) 1975-02-22 1976-02-10 PROCESS FOR THE PRODUCTION OF 7-AMINOCEPHALOSPORIC ACID AND DERIVATIVES
SE7601534A SE7601534L (en) 1975-02-22 1976-02-11 PROCEDURE FOR THE PREPARATION OF 7-AMINOCEFALOSPORANIC ACID DERIVATIVES
FR7603744A FR2301527A1 (en) 1975-02-22 1976-02-11 PROCESS FOR THE PREPARATION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
BE164288A BE838514A (en) 1975-02-22 1976-02-12 PROCESS FOR THE PREPARATION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
AT118476A AT345456B (en) 1975-02-22 1976-02-19 METHOD FOR PRODUCING 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
NL7601662A NL7601662A (en) 1975-02-22 1976-02-19 PROCESS FOR PREPARING DERIVATIVES OF 7-AMINOCEPHALOSPORANIC ACID.
DK72976*#A DK72976A (en) 1975-02-22 1976-02-20 PROCEDURE FOR THE PREPARATION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
CH211176A CH619957A5 (en) 1975-02-22 1976-02-20 Process for the preparation of derivatives of 7-aminocephalosporic acid.
NO760577A NO760577L (en) 1975-02-22 1976-02-20
AU11339/76A AU505037B2 (en) 1975-02-22 1976-02-23 Preparation of 7-aminocephalosporanic acid derivatives
US05/826,371 US4115646A (en) 1975-02-22 1977-08-22 Process for preparing 7-aminocephalosporanic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7546/75A GB1544404A (en) 1975-02-22 1975-02-22 Process for preparing esters of 7-amino-cephalosporanic acid derivatives

Publications (1)

Publication Number Publication Date
GB1544404A true GB1544404A (en) 1979-04-19

Family

ID=9835213

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7546/75A Expired GB1544404A (en) 1975-02-22 1975-02-22 Process for preparing esters of 7-amino-cephalosporanic acid derivatives

Country Status (18)

Country Link
JP (1) JPS51101995A (en)
AR (1) AR212809A1 (en)
AT (1) AT345456B (en)
AU (1) AU505037B2 (en)
BE (1) BE838514A (en)
CA (1) CA1071621A (en)
CH (1) CH619957A5 (en)
DE (1) DE2605159A1 (en)
DK (1) DK72976A (en)
ES (1) ES445009A1 (en)
FI (1) FI760292A (en)
FR (1) FR2301527A1 (en)
GB (1) GB1544404A (en)
IE (1) IE42404B1 (en)
NL (1) NL7601662A (en)
NO (1) NO760577L (en)
SE (1) SE7601534L (en)
ZA (1) ZA76441B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3139534A (en) * 1960-06-17 1964-06-30 Honeywell Regulator Co Pulse characterizing apparatus using saturable core means to effect pulse delay and shaping

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1377661A (en) * 1971-06-05 1974-12-18 Yamanouchi Pharma Co Ltd Oxofuryl ester derivatives of penicillin and cephalosporin
GB1406113A (en) * 1972-10-05 1975-09-17 Leo Pharm Prod Ltd Process for the preparation of cephalosporin estets

Also Published As

Publication number Publication date
BE838514A (en) 1976-08-12
CH619957A5 (en) 1980-10-31
FR2301527B1 (en) 1980-03-07
CA1071621A (en) 1980-02-12
AT345456B (en) 1978-09-25
ATA118476A (en) 1978-01-15
SE7601534L (en) 1976-08-23
NO760577L (en) 1976-08-24
AU1133976A (en) 1977-09-01
JPS51101995A (en) 1976-09-08
ES445009A1 (en) 1977-08-16
NL7601662A (en) 1976-08-24
DE2605159A1 (en) 1976-09-02
ZA76441B (en) 1977-01-26
IE42404L (en) 1976-08-22
AR212809A1 (en) 1978-10-13
AU505037B2 (en) 1979-11-08
FI760292A (en) 1976-08-23
DK72976A (en) 1976-08-23
IE42404B1 (en) 1980-07-30
FR2301527A1 (en) 1976-09-17

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee