GB1543677A - Imino thiazines - Google Patents

Imino thiazines

Info

Publication number
GB1543677A
GB1543677A GB24392/77A GB2439277A GB1543677A GB 1543677 A GB1543677 A GB 1543677A GB 24392/77 A GB24392/77 A GB 24392/77A GB 2439277 A GB2439277 A GB 2439277A GB 1543677 A GB1543677 A GB 1543677A
Authority
GB
United Kingdom
Prior art keywords
thiazines
imino
imino thiazines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB24392/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1543677A publication Critical patent/GB1543677A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB24392/77A 1976-06-15 1977-06-10 Imino thiazines Expired GB1543677A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/696,448 US4054652A (en) 1976-06-15 1976-06-15 Dihydro- and tetrahydro- iminothiazines

Publications (1)

Publication Number Publication Date
GB1543677A true GB1543677A (en) 1979-04-04

Family

ID=24797108

Family Applications (1)

Application Number Title Priority Date Filing Date
GB24392/77A Expired GB1543677A (en) 1976-06-15 1977-06-10 Imino thiazines

Country Status (9)

Country Link
US (1) US4054652A (enExample)
JP (1) JPS52153975A (enExample)
CH (1) CH630373A5 (enExample)
DE (1) DE2726849A1 (enExample)
DK (1) DK144793C (enExample)
FR (1) FR2355012A1 (enExample)
GB (1) GB1543677A (enExample)
NL (1) NL7705961A (enExample)
SE (1) SE7706124L (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629322A (en) * 1994-11-15 1997-05-13 Merck & Co., Inc. Cyclic amidine analogs as inhibitors of nitric oxide synthase
JPH08333258A (ja) 1994-12-14 1996-12-17 Japan Tobacco Inc チアジン又はチアゼピン誘導体及びそれら化合物を含有してなる一酸化窒素合成酵素阻害剤
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
BR112015014349A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc derivados de cloro-pirazina carboxamida úteis para o tratamento de doenças favorecidas por hidratação mucosa insuficiente
US9029382B2 (en) 2012-12-17 2015-05-12 Parion Sciences, Inc. 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492298A (en) * 1968-02-21 1970-01-27 Mcneilab Inc Oxazino-benzothiazine-6,6-dioxides
SU465792A3 (ru) * 1968-11-06 1975-03-30 Хиноин Гиогисцер-Ес Вегиесцети Термекек Гиара Рт (Фирма) Способ получени гетероциклических соединений
BE786956A (fr) * 1971-07-30 1973-01-29 Boehringer Sohn Ingelheim 2h,5,6-dihydro-1,4-oxazines et -thiazines substituees, leurs sels d'addition avec des acides et procede pour les fabriquer

Also Published As

Publication number Publication date
JPS52153975A (en) 1977-12-21
DK144793B (da) 1982-06-07
CH630373A5 (de) 1982-06-15
DK144793C (da) 1982-11-01
DK232677A (da) 1977-12-16
DE2726849A1 (de) 1977-12-29
SE7706124L (sv) 1977-12-16
FR2355012A1 (fr) 1978-01-13
NL7705961A (nl) 1977-12-19
FR2355012B1 (enExample) 1980-10-24
US4054652A (en) 1977-10-18

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee