GB1537874A - Method of preparing stable sterile crystalline cephalosporins for parenteral administration - Google Patents

Method of preparing stable sterile crystalline cephalosporins for parenteral administration

Info

Publication number
GB1537874A
GB1537874A GB14019/76A GB1401976A GB1537874A GB 1537874 A GB1537874 A GB 1537874A GB 14019/76 A GB14019/76 A GB 14019/76A GB 1401976 A GB1401976 A GB 1401976A GB 1537874 A GB1537874 A GB 1537874A
Authority
GB
United Kingdom
Prior art keywords
cephalosporins
parenteral administration
preparing stable
stable sterile
sterile crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB14019/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB1537874A publication Critical patent/GB1537874A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB14019/76A 1975-04-11 1976-04-07 Method of preparing stable sterile crystalline cephalosporins for parenteral administration Expired GB1537874A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/567,224 US4029655A (en) 1975-04-11 1975-04-11 Method of preparing stable sterile crystalline cephalosporins for parenteral administration

Publications (1)

Publication Number Publication Date
GB1537874A true GB1537874A (en) 1979-01-04

Family

ID=24266257

Family Applications (1)

Application Number Title Priority Date Filing Date
GB14019/76A Expired GB1537874A (en) 1975-04-11 1976-04-07 Method of preparing stable sterile crystalline cephalosporins for parenteral administration

Country Status (11)

Country Link
US (2) US4029655A (enExample)
JP (1) JPS51123813A (enExample)
BE (1) BE840280A (enExample)
CA (1) CA1068680A (enExample)
DE (1) DE2614668C2 (enExample)
ES (1) ES446906A1 (enExample)
FR (1) FR2306993A1 (enExample)
GB (1) GB1537874A (enExample)
IE (1) IE42955B1 (enExample)
IL (1) IL49073A (enExample)
NL (1) NL7603659A (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996355A (en) * 1975-01-02 1976-12-07 American Home Products Corporation Permanent suspension pharmaceutical dosage form
IL53427A0 (en) * 1976-11-24 1978-01-31 Lilly Co Eli Method of preparing a rapidly dissolving powder of sterile crystalline cefozolin sodium for parenteral administration
US4115644A (en) * 1977-09-19 1978-09-19 Eli Lilly And Company Process for preparing pure cefamandole from alkali metal and ammonium salts thereof
US4132848A (en) * 1977-11-03 1979-01-02 Eli Lilly And Company Method of preparing a rapidly dissolving powder of crystalline cephalothin sodium for parenteral administration
FR2421905A1 (fr) * 1977-11-24 1979-11-02 Lilly Co Eli Preparation d'une poudre de cephalothine-sodiu m stable, pour administration parenterale
JPS54147917A (en) * 1978-05-08 1979-11-19 Sumitomo Chem Co Ltd Ferrze-drying method
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
JPS60120886A (ja) * 1983-12-02 1985-06-28 Takeda Chem Ind Ltd セフェムカルボン酸のナトリウム塩の結晶
JPH06786B2 (ja) * 1984-02-22 1994-01-05 塩野義製薬株式会社 セフアロチンナトリウムの結晶性凍結乾燥製剤の製造法
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
GB8808433D0 (en) * 1988-04-11 1988-05-11 Merck Sharp & Dohme Therapeutic agents
TW264475B (enExample) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
PT758651E (pt) * 1994-05-02 2002-12-31 Shionogi & Co Cristal de derivado de pirrolidiltiocarbapenem formulacao liofilizada contendo o citado cristal e processo para a producao do mesmo
US20080096858A1 (en) * 2004-04-22 2008-04-24 University Of Connecticut Method of Stabilizing Disordered Cefovecin Sodium Salt
CN101759708B (zh) * 2008-12-23 2012-07-04 深圳信立泰药业股份有限公司 头孢地嗪钠晶型及其制备方法和含有该晶型的药物组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3085884A (en) * 1958-07-28 1963-04-16 Liquefreeze Company Inc Method of freezing and shipping foodstuffs
GB1234802A (en) * 1968-04-19 1971-06-09 British American Tobacco Co Improvements relating to the packing of liquids
US3725003A (en) * 1969-11-04 1973-04-03 Moore Perk Corp Method of sterile packaging

Also Published As

Publication number Publication date
CA1068680A (en) 1979-12-25
DE2614668C2 (de) 1986-10-30
NL7603659A (nl) 1976-10-13
DE2614668A1 (de) 1976-10-21
ES446906A1 (es) 1977-05-16
IE42955L (en) 1976-10-11
IL49073A0 (en) 1976-04-30
BE840280A (fr) 1976-10-01
FR2306993A1 (fr) 1976-11-05
IE42955B1 (en) 1980-11-19
FR2306993B1 (enExample) 1978-11-17
US4104391A (en) 1978-08-01
JPS6143356B2 (enExample) 1986-09-26
US4029655A (en) 1977-06-14
JPS51123813A (en) 1976-10-28
IL49073A (en) 1979-03-12

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee