GB1530997A - Optical analytical method and device - Google Patents

Optical analytical method and device

Info

Publication number
GB1530997A
GB1530997A GB46349/75A GB4634975A GB1530997A GB 1530997 A GB1530997 A GB 1530997A GB 46349/75 A GB46349/75 A GB 46349/75A GB 4634975 A GB4634975 A GB 4634975A GB 1530997 A GB1530997 A GB 1530997A
Authority
GB
United Kingdom
Prior art keywords
waveguide
coating
detected
coating containing
affected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB46349/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of GB1530997A publication Critical patent/GB1530997A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N2021/7706—Reagent provision
    • G01N2021/7709—Distributed reagent, e.g. over length of guide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7783—Transmission, loss

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Light Guides In General And Applications Therefor (AREA)

Abstract

1530997 Analysis by optical methods MONSANTO CO 10 Nov 1975 [11 Nov 1974 26 Sept 1975] 46349/75 Heading G2J [Also in Division G1] The presence and/or quantity of a first material is detected and/or determined by observing the change in optical transmission of a waveguide whose critically reflective surface bears a reagent specifically reactive to said first material. Many examples are given (i) An optical fibre was coated in polyvinyl alcohol containing sodium picrate. Exposure to CN<SP>-</SP> (e.g. aqueous NaCN or gaseous HCN) changed the transmittance of the waveguide. Adsorbed water in the coating affected the results but could be compensated for by monitoring water adsorbtion in white light and correcting for it in measurements taken in green light (the green being complementary to the coloured (red-brown) product of reaction of picrate with CN<SP>-</SP>). Alternatively the waveguide was thoroughly dried before each measurement. (ii) NH 3 detected by reaction with coating containing Fe 2 (SO 4 ) 3 # violet Fe 2 (SO 4 ) 3 À(NH 4 ) 2 SO 4 . (iii) Antigen on fine polystyrene (latex spheres adhered to a waveguide coated with specific antibody. The adhered spheres affected the light transmitting properties of the waveguide (iv) CO 2 detected by a coating containing sodium carbonate/bicarbonate bulks and methyl red (v) SO 3 detected by a coating containing BaCl 2 (vi) Phosgene detected by a coating pdimethyl amino benzaldehyde with dimethyl aniline or p-nitrobenzylpyridine and N-benzylaniline. (vii) Tolylene diisocyanate detected by a coating containing p-dimethylaminobenzaldehyde and acetic acid (viii) SO 2 detected by a coating containing p-phenylenediamine and formaldehyde, or iodine and starch, or potassium tetrachlormercurate with pararosaniline and formaldehyde. A suitable optical arrangement is shown in Fig. 2. Light from lamp 1 is condensed by arrangement 2 and passed through a selectable filter 3. After reflection from a 45 degrees mirror an annular aperture 4 transmits a cylinder of rays which is condensed by optics 5 to a hollow cone of rays which is conducted into the waveguide via a hemisphere and central aperture 6. A detector 8 controls an operational amplifier 9 which drives a digital voltmeter 10. Arrangement 7 supports the waveguide with minimal surface contact. The critical reflective surface of the waveguide may be that between the reactive coating and the case, in which case the sensitivity is low due to only the evanescent waves being affected. Alternatively, if the refractive index of the coating exceeds or equals that of the cone, the coating/air boundary is the critical surface and sensitivity is high.
GB46349/75A 1974-11-11 1975-11-10 Optical analytical method and device Expired GB1530997A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52255874A 1974-11-11 1974-11-11
US61712075A 1975-09-26 1975-09-26

Publications (1)

Publication Number Publication Date
GB1530997A true GB1530997A (en) 1978-11-01

Family

ID=27060857

Family Applications (1)

Application Number Title Priority Date Filing Date
GB46349/75A Expired GB1530997A (en) 1974-11-11 1975-11-10 Optical analytical method and device

Country Status (4)

Country Link
JP (1) JPS5848850B2 (en)
CA (1) CA1058414A (en)
DE (1) DE2550420A1 (en)
GB (1) GB1530997A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2156970A (en) * 1984-01-06 1985-10-16 Plessey Co Plc Optical detection of specific molecules
GB2198844A (en) * 1986-07-17 1988-06-22 Atomic Energy Authority Uk Gas sensor
GB2223841A (en) * 1988-08-31 1990-04-18 Red Kite Tech Parameter measurement using refractive index change

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2837769C2 (en) * 1978-08-30 1983-09-29 Gerhard Prof. Dr.-Ing. 7080 Aalen Müller Device for determining the concentration of biological substances in multi-component systems
DE3135196A1 (en) * 1981-09-05 1983-03-17 Merck Patent Gmbh, 6100 Darmstadt METHOD, MEANS AND DEVICE FOR DETERMINING BIOLOGICAL COMPONENTS
DE3344019C2 (en) * 1983-12-06 1995-05-04 Max Planck Gesellschaft Device for optically measuring the concentration of a component contained in a sample
JPH0664063B2 (en) * 1984-09-21 1994-08-22 コーニング グラス ワークス Waveguide used for spectroscopic analysis and measurement method using the same
DE3617763A1 (en) * 1985-05-28 1986-12-04 Olympus Optical Co., Ltd., Tokio/Tokyo METHOD FOR CARRYING OUT IMMUNOLOGICAL PROVISIONS AND APPARATUS APPARATUS FOR THIS
JP2506761B2 (en) * 1987-05-14 1996-06-12 株式会社リコー Gas detector
JPH03212561A (en) * 1990-01-16 1991-09-18 Takashi Takee Form device for concrete
JP2007306414A (en) * 2006-05-12 2007-11-22 Mitsubishi Motors Corp Loading structure of on-vehicle speaker
JP2016180608A (en) * 2015-03-23 2016-10-13 株式会社トクヤマ Detector detecting by ultraviolet light absorption

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3436159A (en) * 1966-02-04 1969-04-01 Bausch & Lomb Internal reflection element for spectroscopy with film optical cavity to enhance absorption
US3515490A (en) * 1967-04-11 1970-06-02 Philips Corp Sample cell for detection of an atmospheric contaminant by internal reflection spectrometry
US3715585A (en) * 1971-06-07 1973-02-06 N Harrick Fluorescence spectrophotometry using multiple reflections to enhance sample absorption and fluorescence collection

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2156970A (en) * 1984-01-06 1985-10-16 Plessey Co Plc Optical detection of specific molecules
GB2198844A (en) * 1986-07-17 1988-06-22 Atomic Energy Authority Uk Gas sensor
GB2198844B (en) * 1986-07-17 1990-03-28 Atomic Energy Authority Uk Sensor
GB2223841A (en) * 1988-08-31 1990-04-18 Red Kite Tech Parameter measurement using refractive index change

Also Published As

Publication number Publication date
JPS5848850B2 (en) 1983-10-31
DE2550420A1 (en) 1976-05-13
JPS5170694A (en) 1976-06-18
CA1058414A (en) 1979-07-17

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee