GB1529326A - Boron esters and their use in a process for synthesis of coenzymes q - Google Patents
Boron esters and their use in a process for synthesis of coenzymes qInfo
- Publication number
- GB1529326A GB1529326A GB47905/75A GB4790575A GB1529326A GB 1529326 A GB1529326 A GB 1529326A GB 47905/75 A GB47905/75 A GB 47905/75A GB 4790575 A GB4790575 A GB 4790575A GB 1529326 A GB1529326 A GB 1529326A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzohydroquinone
- boron
- prepared
- ester
- benzoquinones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001638 boron Chemical class 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000005515 coenzyme Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- -1 boron ester Chemical class 0.000 abstract 4
- 229910052796 boron Inorganic materials 0.000 abstract 3
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N 1,4-Benzenediol Natural products OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 abstract 2
- 150000004054 benzoquinones Chemical class 0.000 abstract 2
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 abstract 2
- 150000005208 1,4-dihydroxybenzenes Chemical class 0.000 abstract 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 abstract 1
- 229910021538 borax Inorganic materials 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 abstract 1
- CPJRRXSHAYUTGL-UHFFFAOYSA-N isopentenyl alcohol Chemical compound CC(=C)CCO CPJRRXSHAYUTGL-UHFFFAOYSA-N 0.000 abstract 1
- 229910000464 lead oxide Inorganic materials 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- YEXPOXQUZXUXJW-UHFFFAOYSA-N oxolead Chemical compound [Pb]=O YEXPOXQUZXUXJW-UHFFFAOYSA-N 0.000 abstract 1
- ASUAYTHWZCLXAN-UHFFFAOYSA-N prenol Chemical compound CC(C)=CCO ASUAYTHWZCLXAN-UHFFFAOYSA-N 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 229910001923 silver oxide Inorganic materials 0.000 abstract 1
- 239000004328 sodium tetraborate Substances 0.000 abstract 1
- 235000010339 sodium tetraborate Nutrition 0.000 abstract 1
- DSBZYDDWLLIJJS-UHFFFAOYSA-N ubiquinol-0 Chemical compound COC1=C(O)C=C(C)C(O)=C1OC DSBZYDDWLLIJJS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1529326 Boron esters and benzoquinones prepared therefrom EISAI CO Ltd 21 Nov 1975 [22 Nov 1974] 47905/75 Headings C2B and C2C A boron ester of a 1,4-benzohydroquinone of formula where R is a group in which S is O or 1-11 and A and B are each H or together form a direct bond, is prepared by reacting a boron ester of 2,3-dimethoxy-5- methyl-1,4-benzohydroquinone with a prenol or isoprenol or reactive derivative thereof. The ester reactant may be obtained by reaction of the 2,3,5-substituted hydroquinone with H 3 BO 3 , HBO 2 , B 2 O 3 or borax and may also be of the type the free OH groups of which may be further esterified with the hydroquinone compound. Pharmaceutically active benzoquinones of formula are prepared by reacting a boron ester of a 1,4- benzohydroquinone II with a mild oxidant such as silver oxide, lead oxide or ferric chloride.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49133573A JPS5826327B2 (en) | 1974-11-22 | 1974-11-22 | Hokosokyuuruino Goseihou |
| US05/725,427 US4057568A (en) | 1974-11-22 | 1976-09-22 | Process for synthesis of boric acid ester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1529326A true GB1529326A (en) | 1978-10-18 |
Family
ID=26467897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB47905/75A Expired GB1529326A (en) | 1974-11-22 | 1975-11-21 | Boron esters and their use in a process for synthesis of coenzymes q |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5826327B2 (en) |
| CH (1) | CH613682A5 (en) |
| DE (1) | DE2552365C2 (en) |
| FR (1) | FR2291980A1 (en) |
| GB (1) | GB1529326A (en) |
| NL (1) | NL184778C (en) |
| SE (1) | SE431325B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6058209B2 (en) | 1978-12-01 | 1985-12-19 | エーザイ株式会社 | β,γ-dihydropolyprenyl alcohol and antihypertensive agents consisting of it |
| JPH0221944Y2 (en) * | 1986-03-26 | 1990-06-13 | ||
| JPH0541417U (en) * | 1991-03-20 | 1993-06-08 | ハクバ写真産業株式会社 | Handle of the trunk case |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH376898A (en) * | 1958-08-07 | 1964-04-30 | Hoffmann La Roche | Process for the preparation of 2,3-dimethoxy-5-methyl-benzohydroquinones- (1,4) or benzoquinones- (1,4) substituted in the 6-position |
-
1974
- 1974-11-22 JP JP49133573A patent/JPS5826327B2/en not_active Expired
-
1975
- 1975-11-19 CH CH1497975A patent/CH613682A5/en not_active IP Right Cessation
- 1975-11-21 GB GB47905/75A patent/GB1529326A/en not_active Expired
- 1975-11-21 SE SE7513127A patent/SE431325B/en not_active IP Right Cessation
- 1975-11-21 DE DE2552365A patent/DE2552365C2/en not_active Expired
- 1975-11-24 FR FR7535860A patent/FR2291980A1/en active Granted
- 1975-11-24 NL NLAANVRAGE7513705,A patent/NL184778C/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2552365A1 (en) | 1976-05-26 |
| SE431325B (en) | 1984-01-30 |
| FR2291980B1 (en) | 1978-05-12 |
| CH613682A5 (en) | 1979-10-15 |
| DE2552365C2 (en) | 1985-10-24 |
| JPS5826327B2 (en) | 1983-06-02 |
| SE7513127L (en) | 1976-05-24 |
| FR2291980A1 (en) | 1976-06-18 |
| JPS5163139A (en) | 1976-06-01 |
| NL184778C (en) | 1989-11-01 |
| NL7513705A (en) | 1976-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |