GB1514543A - Process for the preparation of 9,11,15-trihydroxy-13,14-dehydro prostanoic acid derivatives - Google Patents
Process for the preparation of 9,11,15-trihydroxy-13,14-dehydro prostanoic acid derivativesInfo
- Publication number
- GB1514543A GB1514543A GB29939/77A GB2993977A GB1514543A GB 1514543 A GB1514543 A GB 1514543A GB 29939/77 A GB29939/77 A GB 29939/77A GB 2993977 A GB2993977 A GB 2993977A GB 1514543 A GB1514543 A GB 1514543A
- Authority
- GB
- United Kingdom
- Prior art keywords
- configuration
- formula
- chain
- resulting
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- WGJJROVFWIXTPA-OALUTQOASA-N prostanoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC(O)=O WGJJROVFWIXTPA-OALUTQOASA-N 0.000 title 1
- 229910052799 carbon Inorganic materials 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 150000002596 lactones Chemical class 0.000 abstract 2
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 2
- 150000003180 prostaglandins Chemical class 0.000 abstract 2
- 101000837626 Homo sapiens Thyroid hormone receptor alpha Proteins 0.000 abstract 1
- 102100028702 Thyroid hormone receptor alpha Human genes 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2733374 | 1974-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1514543A true GB1514543A (en) | 1978-06-14 |
Family
ID=11221442
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32731/75A Expired GB1514542A (en) | 1974-09-17 | 1975-08-05 | Prostaglandins |
| GB29939/77A Expired GB1514543A (en) | 1974-09-17 | 1975-08-05 | Process for the preparation of 9,11,15-trihydroxy-13,14-dehydro prostanoic acid derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32731/75A Expired GB1514542A (en) | 1974-09-17 | 1975-08-05 | Prostaglandins |
Country Status (20)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4220759A (en) * | 1975-03-14 | 1980-09-02 | Carlo Erba S.P.A. | 13,14-Dehydro-11-deoxy-prostaglandins and process for their preparation |
| HU178202B (en) * | 1977-09-26 | 1982-03-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new,optically active and racemic bicyclic acetals and merkaptals |
| WO2007041273A2 (en) * | 2005-09-29 | 2007-04-12 | Eastar Chemical Corp. | Process for the production of intermediates for making prostaglandin derivatives such as latanoprost, travaprost, and bimatoprost |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1425962A (en) * | 1972-04-13 | 1976-02-25 | Erba Carlo Spa | Lactols and lactones |
-
1975
- 1975-07-29 NO NO752675A patent/NO150117C/no unknown
- 1975-07-29 US US05/600,187 patent/US4041064A/en not_active Expired - Lifetime
- 1975-07-31 DK DK348575A patent/DK348575A/da not_active Application Discontinuation
- 1975-08-05 GB GB32731/75A patent/GB1514542A/en not_active Expired
- 1975-08-05 GB GB29939/77A patent/GB1514543A/en not_active Expired
- 1975-08-14 FI FI752303A patent/FI752303A/fi not_active Application Discontinuation
- 1975-08-15 JP JP50099416A patent/JPS5929075B2/ja not_active Expired
- 1975-08-19 ZA ZA755310A patent/ZA755310B/xx unknown
- 1975-08-22 DE DE19752537406 patent/DE2537406A1/de not_active Withdrawn
- 1975-08-28 FR FR7526557A patent/FR2313028A1/fr active Granted
- 1975-08-28 SU SU752163240A patent/SU942588A3/ru active
- 1975-08-28 CS CS755872A patent/CS191274B2/cs unknown
- 1975-08-28 CA CA234,430A patent/CA1098126A/en not_active Expired
- 1975-08-28 NL NL7510191A patent/NL7510191A/xx not_active Application Discontinuation
- 1975-08-29 SE SE7509607A patent/SE423992B/xx not_active IP Right Cessation
- 1975-08-29 BE BE159585A patent/BE832891A/xx not_active IP Right Cessation
- 1975-08-29 HU HU75EA151A patent/HU175345B/hu unknown
- 1975-09-01 IL IL48027A patent/IL48027A/xx unknown
- 1975-09-01 CH CH1126275A patent/CH614936A5/xx not_active IP Right Cessation
-
1978
- 1978-08-22 SE SE7808849A patent/SE427556B/sv not_active IP Right Cessation
-
1979
- 1979-01-18 HK HK40/79A patent/HK4079A/xx unknown
- 1979-08-16 CH CH752979A patent/CH617424A5/de not_active IP Right Cessation
-
1980
- 1980-12-30 MY MY16/80A patent/MY8000016A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH617424A5 (US08142518-20120327-C00011.png) | 1980-05-30 |
| SE427556B (sv) | 1983-04-18 |
| FI752303A (US08142518-20120327-C00011.png) | 1976-03-18 |
| HK4079A (en) | 1979-01-26 |
| FR2313028B1 (US08142518-20120327-C00011.png) | 1980-05-30 |
| NO752675L (US08142518-20120327-C00011.png) | 1976-03-18 |
| US4041064A (en) | 1977-08-09 |
| DK348575A (da) | 1976-03-18 |
| SU942588A3 (ru) | 1982-07-07 |
| CS191274B2 (en) | 1979-06-29 |
| SE7808849L (sv) | 1978-08-22 |
| ZA755310B (en) | 1977-04-27 |
| FR2313028A1 (fr) | 1976-12-31 |
| JPS5929075B2 (ja) | 1984-07-18 |
| MY8000016A (en) | 1980-12-31 |
| IL48027A (en) | 1980-03-31 |
| CH614936A5 (US08142518-20120327-C00011.png) | 1979-12-28 |
| HU175345B (hu) | 1980-07-28 |
| NO150117C (no) | 1984-08-22 |
| SE423992B (sv) | 1982-06-21 |
| GB1514542A (en) | 1978-06-14 |
| IL48027A0 (en) | 1975-11-25 |
| CA1098126A (en) | 1981-03-24 |
| NO150117B (no) | 1984-05-14 |
| DE2537406A1 (de) | 1976-08-12 |
| JPS5143745A (en) | 1976-04-14 |
| SE7509607L (sv) | 1976-03-18 |
| NL7510191A (nl) | 1976-03-19 |
| BE832891A (fr) | 1976-03-01 |
| AU8350075A (en) | 1977-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |