GB1512057A - Difluoro-steroids and processes for their manufacture - Google Patents
Difluoro-steroids and processes for their manufactureInfo
- Publication number
- GB1512057A GB1512057A GB31177/75A GB3117775A GB1512057A GB 1512057 A GB1512057 A GB 1512057A GB 31177/75 A GB31177/75 A GB 31177/75A GB 3117775 A GB3117775 A GB 3117775A GB 1512057 A GB1512057 A GB 1512057A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- radical
- oxo
- groups
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 150000003431 steroids Chemical class 0.000 abstract 6
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000004043 oxo group Chemical group O=* 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 238000001794 hormone therapy Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1047874A CH606090A5 (enExample) | 1974-07-30 | 1974-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1512057A true GB1512057A (en) | 1978-05-24 |
Family
ID=4363664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB31177/75A Expired GB1512057A (en) | 1974-07-30 | 1975-07-25 | Difluoro-steroids and processes for their manufacture |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4092310A (enExample) |
| JP (1) | JPS5134142A (enExample) |
| CA (1) | CA1058159A (enExample) |
| CH (1) | CH606090A5 (enExample) |
| DE (1) | DE2533496A1 (enExample) |
| DK (1) | DK143138C (enExample) |
| FR (1) | FR2280382A1 (enExample) |
| GB (1) | GB1512057A (enExample) |
| NL (1) | NL7509089A (enExample) |
| SE (1) | SE7507169L (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU572589B2 (en) | 1983-12-14 | 1988-05-12 | Upjohn Company, The | 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids |
| US6046185A (en) * | 1996-07-11 | 2000-04-04 | Inflazyme Pharmaceuticals Ltd. | 6,7-oxygenated steroids and uses related thereto |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3318922A (en) * | 1962-10-01 | 1967-05-09 | Merck & Co Inc | 13-substituted alkyl-17-hydroxygona-4-en-3-ones and their 17alpha substitution products |
| US3914265A (en) * | 1972-12-11 | 1975-10-21 | Du Pont | Dialkylaminosulfur trifluorides as fluorinating agents |
-
1974
- 1974-07-30 CH CH1047874A patent/CH606090A5/xx not_active IP Right Cessation
-
1975
- 1975-06-16 DK DK271275A patent/DK143138C/da active
- 1975-06-23 SE SE7507169A patent/SE7507169L/xx unknown
- 1975-06-24 JP JP50077137A patent/JPS5134142A/ja active Pending
- 1975-07-23 US US05/598,300 patent/US4092310A/en not_active Expired - Lifetime
- 1975-07-25 GB GB31177/75A patent/GB1512057A/en not_active Expired
- 1975-07-26 DE DE19752533496 patent/DE2533496A1/de not_active Withdrawn
- 1975-07-28 CA CA232,334A patent/CA1058159A/en not_active Expired
- 1975-07-30 FR FR7523761A patent/FR2280382A1/fr active Granted
- 1975-07-30 NL NL7509089A patent/NL7509089A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2533496A1 (de) | 1976-02-19 |
| SE7507169L (sv) | 1976-02-02 |
| CA1058159A (en) | 1979-07-10 |
| DK143138B (da) | 1981-06-29 |
| DK271275A (da) | 1976-01-31 |
| DK143138C (da) | 1981-11-09 |
| FR2280382B1 (enExample) | 1980-04-18 |
| FR2280382A1 (fr) | 1976-02-27 |
| US4092310A (en) | 1978-05-30 |
| NL7509089A (nl) | 1976-02-03 |
| CH606090A5 (enExample) | 1978-10-13 |
| JPS5134142A (enExample) | 1976-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |