GB1500127A - Reactive matrices - Google Patents

Reactive matrices

Info

Publication number
GB1500127A
GB1500127A GB4720273A GB4720273A GB1500127A GB 1500127 A GB1500127 A GB 1500127A GB 4720273 A GB4720273 A GB 4720273A GB 4720273 A GB4720273 A GB 4720273A GB 1500127 A GB1500127 A GB 1500127A
Authority
GB
United Kingdom
Prior art keywords
compound
metal substrate
organic compound
assayed
biological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4720273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Priority to GB4720273A priority Critical patent/GB1500127A/en
Publication of GB1500127A publication Critical patent/GB1500127A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/40—Magnetic particle immunoreagent carriers the magnetic material being dispersed in the monomer composition prior to polymerisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

1500127 Test composite comprising metal substrate ABBOTT LABORATORIES 10 Jan 1975 [10 Oct 1973] 47202/73 Heading G1B [Also in Division C3] A water-insoluble composition or composite body for use in testing comprises a metal substrate the surface of which is coated with an intermediate polymer comprising a condensation product on an aminobenzoic acid and an aldehyde to which is coupled an organic compound having biological or chemical activity, the composition or composite body exhibiting the biological or chemical activity of or related to that of the unbound organic compound. The substrate may be metal in the form for example of powder, rods or bars or may be used as "magnetic plastic". The polymer layer forms a continuous adherent coating on the metal substrate and may be macroporous. Organic compounds exemplified are beta-D-glucosidase, and antibody to follicle stimulating hormone. There is general reference to use in testing of composites in which the organic compound is the compound to be assayed or a labelled version of the latter, or a labelled or unlabelled specific reagent for the compound to be assayed. Reference has been directed by the Comptroller to Specification 1403359.
GB4720273A 1973-10-10 1973-10-10 Reactive matrices Expired GB1500127A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4720273A GB1500127A (en) 1973-10-10 1973-10-10 Reactive matrices

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4720273A GB1500127A (en) 1973-10-10 1973-10-10 Reactive matrices

Publications (1)

Publication Number Publication Date
GB1500127A true GB1500127A (en) 1978-02-08

Family

ID=10444120

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4720273A Expired GB1500127A (en) 1973-10-10 1973-10-10 Reactive matrices

Country Status (1)

Country Link
GB (1) GB1500127A (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408142A1 (en) * 1977-11-03 1979-06-01 Du Pont IMMUNOCHEMICAL DETERMINATION PROCESS USING BRANDED REAGENTS
EP0211436A2 (en) * 1985-08-07 1987-02-25 Tosoh Corporation Stirrer for biochemical reactions
US4666697A (en) * 1982-12-08 1987-05-19 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic agent
EP0339821A1 (en) * 1988-04-21 1989-11-02 United Kingdom Atomic Energy Authority Bonding to metal surfaces
US5705402A (en) * 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5770459A (en) * 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5798083A (en) * 1988-11-03 1998-08-25 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration and chemiluminescence detection
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US6078782A (en) * 1988-11-03 2000-06-20 Igen International Inc. Methods for improved particle electrochemiluminescence assays
US6325973B1 (en) 1991-02-06 2001-12-04 Igen International, Inc. Methods and apparatus for improved luminescence assays
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US8211279B2 (en) 2005-06-03 2012-07-03 Board Of Regents Of The University Of Texas System Electrochemistry and electrogenerated chemiluminescence with a single faradaic electrode

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408142A1 (en) * 1977-11-03 1979-06-01 Du Pont IMMUNOCHEMICAL DETERMINATION PROCESS USING BRANDED REAGENTS
US4666697A (en) * 1982-12-08 1987-05-19 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic agent
EP0211436A2 (en) * 1985-08-07 1987-02-25 Tosoh Corporation Stirrer for biochemical reactions
EP0211436A3 (en) * 1985-08-07 1987-09-23 Toyo Soda Manufacturing Co., Ltd. Stirrer for biochemical reactions
US5770459A (en) * 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
EP0339821A1 (en) * 1988-04-21 1989-11-02 United Kingdom Atomic Energy Authority Bonding to metal surfaces
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5798083A (en) * 1988-11-03 1998-08-25 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration and chemiluminescence detection
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US6078782A (en) * 1988-11-03 2000-06-20 Igen International Inc. Methods for improved particle electrochemiluminescence assays
US5705402A (en) * 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US6325973B1 (en) 1991-02-06 2001-12-04 Igen International, Inc. Methods and apparatus for improved luminescence assays
US8211279B2 (en) 2005-06-03 2012-07-03 Board Of Regents Of The University Of Texas System Electrochemistry and electrogenerated chemiluminescence with a single faradaic electrode
US8702958B2 (en) 2005-06-03 2014-04-22 Board Of Regents Of The University Of Texas System Electrochemistry and electrogenerated chemiluminescence with a single faradaic electrode
US8840774B2 (en) 2005-06-03 2014-09-23 Board Of Regents Of The University Of Texas System Electrochemistry and electrogenerated chemiluminescence with a single faradaic electrode

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years

Effective date: 19950109