GB1493941A - Pharmaceutical product for treatment of all leukaemia forms and neurotic syndromes - Google Patents
Pharmaceutical product for treatment of all leukaemia forms and neurotic syndromesInfo
- Publication number
- GB1493941A GB1493941A GB33039/74A GB3303974A GB1493941A GB 1493941 A GB1493941 A GB 1493941A GB 33039/74 A GB33039/74 A GB 33039/74A GB 3303974 A GB3303974 A GB 3303974A GB 1493941 A GB1493941 A GB 1493941A
- Authority
- GB
- United Kingdom
- Prior art keywords
- indole
- treatment
- tryptamine
- aminoethyl
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 208000032839 leukemia Diseases 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 4
- JTEJPPKMYBDEMY-UHFFFAOYSA-N 5-methoxytryptamine Chemical compound COC1=CC=C2NC=C(CCN)C2=C1 JTEJPPKMYBDEMY-UHFFFAOYSA-N 0.000 abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- LMIQERWZRIFWNZ-UHFFFAOYSA-N 5-hydroxyindole Chemical compound OC1=CC=C2NC=CC2=C1 LMIQERWZRIFWNZ-UHFFFAOYSA-N 0.000 abstract 2
- 235000000177 Indigofera tinctoria Nutrition 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 229940097275 indigo Drugs 0.000 abstract 2
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 abstract 2
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 2
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 2
- AHXNCCMSLCCEAD-UHFFFAOYSA-N 1-[3-(2-aminoethyl)-1h-indol-5-yl]-2-hydroxyethanone Chemical compound C1=C(C(=O)CO)C=C2C(CCN)=CNC2=C1 AHXNCCMSLCCEAD-UHFFFAOYSA-N 0.000 abstract 1
- MWXGHSLSDGMCCC-UHFFFAOYSA-N 2-(1H-indol-5-ylmethoxy)ethanamine Chemical compound NCCOCC=1C=C2C=CNC2=CC1 MWXGHSLSDGMCCC-UHFFFAOYSA-N 0.000 abstract 1
- VKPPFDPXZWFDFA-UHFFFAOYSA-N 2-chloroethanamine Chemical compound NCCCl VKPPFDPXZWFDFA-UHFFFAOYSA-N 0.000 abstract 1
- 229940097276 5-methoxytryptamine Drugs 0.000 abstract 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 abstract 1
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 abstract 1
- 239000012346 acetyl chloride Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N dimethyl sulfate Chemical compound COS(=O)(=O)OC VAYGXNSJCAHWJZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 abstract 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 1
- 238000000197 pyrolysis Methods 0.000 abstract 1
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT4011573 | 1973-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1493941A true GB1493941A (en) | 1977-11-30 |
Family
ID=11248376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB33039/74A Expired GB1493941A (en) | 1973-12-31 | 1974-12-31 | Pharmaceutical product for treatment of all leukaemia forms and neurotic syndromes |
Country Status (10)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989004659A1 (en) * | 1987-11-19 | 1989-06-01 | Cellena (Cell Engineering) A.G. | Use of melatonin or derivatives thereof for the production of pharmaceutical compositions effective to counteract the effects of aging |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4506080A (en) * | 1983-07-01 | 1985-03-19 | Nestec S. A. | Preparation of serotonine and derivatives |
| GR900100024A (el) * | 1989-01-17 | 1991-06-07 | Amr Int | Μέθοδος θεραπείας του προεμμηνορροϊκού συνδρόμου. |
| IT1243193B (it) * | 1990-08-10 | 1994-05-24 | Medea Res Srl | Composizioni farmaceutiche orali a base di melatonina |
-
1974
- 1974-07-19 DE DE2435365A patent/DE2435365A1/de active Pending
- 1974-07-26 AT AT617674A patent/ATA617674A/de not_active Application Discontinuation
- 1974-08-01 AU AU71949/74A patent/AU7194974A/en not_active Expired
- 1974-11-28 FR FR7440379A patent/FR2255897A1/fr not_active Withdrawn
- 1974-12-11 CH CH1649974A patent/CH625218A5/it not_active IP Right Cessation
- 1974-12-27 JP JP49149047A patent/JPS5096565A/ja active Pending
- 1974-12-30 ZA ZA00748264A patent/ZA748264B/xx unknown
- 1974-12-31 NL NL7417046A patent/NL7417046A/xx unknown
- 1974-12-31 GB GB33039/74A patent/GB1493941A/en not_active Expired
- 1974-12-31 BE BE152074A patent/BE824022A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989004659A1 (en) * | 1987-11-19 | 1989-06-01 | Cellena (Cell Engineering) A.G. | Use of melatonin or derivatives thereof for the production of pharmaceutical compositions effective to counteract the effects of aging |
Also Published As
| Publication number | Publication date |
|---|---|
| CH625218A5 (en) | 1981-09-15 |
| ZA748264B (en) | 1976-01-28 |
| FR2255897A1 (enrdf_load_stackoverflow) | 1975-07-25 |
| NL7417046A (nl) | 1975-07-02 |
| AU7194974A (en) | 1976-02-05 |
| JPS5096565A (enrdf_load_stackoverflow) | 1975-07-31 |
| DE2435365A1 (de) | 1976-01-29 |
| ATA617674A (de) | 1976-11-15 |
| BE824022A (fr) | 1975-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |