GB1493092A - Compositions containing prostaglandins - Google Patents
Compositions containing prostaglandinsInfo
- Publication number
- GB1493092A GB1493092A GB9508/76A GB950876A GB1493092A GB 1493092 A GB1493092 A GB 1493092A GB 9508/76 A GB9508/76 A GB 9508/76A GB 950876 A GB950876 A GB 950876A GB 1493092 A GB1493092 A GB 1493092A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compositions containing
- triacetin
- march
- containing prostaglandins
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 abstract 4
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 abstract 2
- -1 PGE prostaglandin Chemical class 0.000 abstract 2
- 235000013773 glyceryl triacetate Nutrition 0.000 abstract 2
- 239000001087 glyceryl triacetate Substances 0.000 abstract 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
- 229960002622 triacetin Drugs 0.000 abstract 2
- JWZZKOKVBUJMES-UHFFFAOYSA-N (+-)-Isoprenaline Chemical compound CC(C)NCC(O)C1=CC=C(O)C(O)=C1 JWZZKOKVBUJMES-UHFFFAOYSA-N 0.000 abstract 1
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 1
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 abstract 1
- 101800000989 Oxytocin Proteins 0.000 abstract 1
- 102100031951 Oxytocin-neurophysin 1 Human genes 0.000 abstract 1
- 239000000150 Sympathomimetic Substances 0.000 abstract 1
- 229960003556 aminophylline Drugs 0.000 abstract 1
- FQPFAHBPWDRTLU-UHFFFAOYSA-N aminophylline Chemical compound NCCN.O=C1N(C)C(=O)N(C)C2=C1NC=N2.O=C1N(C)C(=O)N(C)C2=C1NC=N2 FQPFAHBPWDRTLU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 229960001334 corticosteroids Drugs 0.000 abstract 1
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 abstract 1
- 229960000258 corticotropin Drugs 0.000 abstract 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 abstract 1
- 229960002179 ephedrine Drugs 0.000 abstract 1
- 229960003133 ergot alkaloid Drugs 0.000 abstract 1
- 229940039009 isoproterenol Drugs 0.000 abstract 1
- 229940083747 low-ceiling diuretics xanthine derivative Drugs 0.000 abstract 1
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 abstract 1
- 229960001723 oxytocin Drugs 0.000 abstract 1
- 229960005205 prednisolone Drugs 0.000 abstract 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 abstract 1
- 230000001975 sympathomimetic effect Effects 0.000 abstract 1
- 229940064707 sympathomimetics Drugs 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/562,535 US3966962A (en) | 1975-03-27 | 1975-03-27 | Triacetin solutions of PGE-type compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1493092A true GB1493092A (en) | 1977-11-23 |
Family
ID=24246672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB9508/76A Expired GB1493092A (en) | 1975-03-27 | 1976-03-10 | Compositions containing prostaglandins |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3966962A (enExample) |
| JP (1) | JPS6020365B2 (enExample) |
| BE (1) | BE840075A (enExample) |
| CA (1) | CA1044140A (enExample) |
| DE (1) | DE2611183C2 (enExample) |
| FR (1) | FR2305177A1 (enExample) |
| GB (1) | GB1493092A (enExample) |
| HK (1) | HK10481A (enExample) |
| MX (1) | MX3794E (enExample) |
| NL (1) | NL190539C (enExample) |
| ZA (1) | ZA761306B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU510190B2 (en) * | 1976-08-14 | 1980-06-12 | Carlson, Lars A | Prostaglandin method |
| DE2740953A1 (de) * | 1977-09-12 | 1979-03-22 | Thera Ges Fuer Patente | Verwendung von prostaglandinen zur senkung des blutzuckerspiegels |
| US4301175A (en) * | 1980-12-29 | 1981-11-17 | The Upjohn Company | E-Type prostaglandin compositions |
| ZA831186B (en) * | 1982-03-22 | 1983-11-30 | Upjohn Ltd | Gelled pge2/triacetin solutions |
| ZA835226B (en) * | 1982-07-19 | 1985-03-27 | Syntex Inc | Pge-type compositions encapsulated by acid isolated gelatin |
| US4431833A (en) * | 1982-12-27 | 1984-02-14 | American Cyanamid Company | Prostaglandin and hydroxylated fatty acid ester formulations |
| US4820732A (en) * | 1985-10-04 | 1989-04-11 | The Upjohn Company | Method and compositions for reducing dysfunction in angioplasty procedures |
| US4955878A (en) * | 1986-04-04 | 1990-09-11 | Biotechnology, Inc. | Kit for preventing or treating arterial dysfunction resulting from angioplasty procedures |
| JP3756512B2 (ja) * | 1992-09-21 | 2006-03-15 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 徐放性タンパク質製剤 |
| BRPI0014869B8 (pt) * | 1999-10-15 | 2021-05-25 | Sucampo Ag | prostaglandinas bicíclicas, composições estabilizadas das mesmas, bem como processo para sua estabilização |
| US20100286101A1 (en) * | 2009-05-07 | 2010-11-11 | Jason Carbol | Pharmaceutical composition including a corticosteroid and a vitamin d analog having improved stability |
| WO2015200444A1 (en) * | 2014-06-24 | 2015-12-30 | Saudi Arabian Oil Company | Encapsulation of an acid precursor for oil field applications |
| US20230338322A1 (en) * | 2020-05-04 | 2023-10-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Glyceryltriacetate (gta) for use in improving breathing |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA721937B (en) * | 1971-10-22 | 1972-12-27 | Upjohn Co | Pharmaceutical preparations and uses thereof |
| US3829579A (en) * | 1971-11-01 | 1974-08-13 | Upjohn Co | Stable solutions of pge-type compounds |
| US3833725A (en) * | 1972-12-08 | 1974-09-03 | Syntex Corp | Dialkylated glycol compositions and medicament preparations containing same |
| JPS5729463B2 (enExample) * | 1973-12-07 | 1982-06-23 |
-
1975
- 1975-03-27 US US05/562,535 patent/US3966962A/en not_active Expired - Lifetime
-
1976
- 1976-02-11 CA CA245,490A patent/CA1044140A/en not_active Expired
- 1976-02-26 MX MX7623U patent/MX3794E/es unknown
- 1976-03-04 ZA ZA761306A patent/ZA761306B/xx unknown
- 1976-03-10 JP JP51025163A patent/JPS6020365B2/ja not_active Expired
- 1976-03-10 GB GB9508/76A patent/GB1493092A/en not_active Expired
- 1976-03-17 DE DE2611183A patent/DE2611183C2/de not_active Expired
- 1976-03-24 NL NLAANVRAGE7603064,A patent/NL190539C/xx not_active IP Right Cessation
- 1976-03-26 FR FR7608916A patent/FR2305177A1/fr active Granted
- 1976-03-26 BE BE165594A patent/BE840075A/xx not_active IP Right Cessation
-
1981
- 1981-03-19 HK HK104/81A patent/HK10481A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL190539C (nl) | 1994-04-18 |
| JPS6020365B2 (ja) | 1985-05-21 |
| DE2611183C2 (de) | 1985-08-14 |
| DE2611183A1 (de) | 1976-10-14 |
| FR2305177A1 (fr) | 1976-10-22 |
| FR2305177B1 (enExample) | 1982-10-08 |
| CA1044140A (en) | 1978-12-12 |
| HK10481A (en) | 1981-03-27 |
| NL7603064A (nl) | 1976-09-29 |
| AU1194876A (en) | 1977-09-15 |
| BE840075A (fr) | 1976-09-27 |
| MX3794E (es) | 1981-07-22 |
| JPS51112508A (en) | 1976-10-05 |
| ZA761306B (en) | 1977-02-23 |
| NL190539B (nl) | 1993-11-16 |
| US3966962A (en) | 1976-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19960309 |