GB1492023A - Aescin polysulphuric acid esters - Google Patents
Aescin polysulphuric acid estersInfo
- Publication number
- GB1492023A GB1492023A GB28231/76A GB2823176A GB1492023A GB 1492023 A GB1492023 A GB 1492023A GB 28231/76 A GB28231/76 A GB 28231/76A GB 2823176 A GB2823176 A GB 2823176A GB 1492023 A GB1492023 A GB 1492023A
- Authority
- GB
- United Kingdom
- Prior art keywords
- escin
- esters
- polysulphate
- july
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 3
- YFESOSRPNPYODN-RSMWSHJLSA-N (2s,3s,4s,5r,6r)-6-[[(4s,6ar,6bs,8r,8ar,9r,10r,14br)-9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(z)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2s,3r,4s, Chemical compound O([C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)OC1CC[C@]2(C)C3CC=C4[C@@]([C@@]3(CCC2[C@]1(CO)C)C)(C)C[C@@H](O)[C@@]1(CO)[C@@H](OC(C)=O)[C@@H](C(CC14)(C)C)OC(=O)C(\C)=C/C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.O([C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)OC1CC[C@]2(C)C3CC=C4[C@@]([C@@]3(CCC2[C@]1(CO)C)C)(C)C[C@@H](O)[C@@]1(CO)[C@@H](OC(C)=O)[C@@H](C(CC14)(C)C)OC(=O)C(/C)=C/C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YFESOSRPNPYODN-RSMWSHJLSA-N 0.000 title 1
- AXNVHPCVMSNXNP-GKTCLTPXSA-N Aescin Natural products O=C(O[C@H]1[C@@H](OC(=O)C)[C@]2(CO)[C@@H](O)C[C@@]3(C)[C@@]4(C)[C@@H]([C@]5(C)[C@H]([C@](CO)(C)[C@@H](O[C@@H]6[C@@H](O[C@H]7[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)[C@@H](O)[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O7)[C@@H](C(=O)O)O6)CC5)CC4)CC=C3[C@@H]2CC1(C)C)/C(=C/C)/C AXNVHPCVMSNXNP-GKTCLTPXSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 229940011399 escin Drugs 0.000 abstract 5
- 229930186222 escin Natural products 0.000 abstract 5
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- 241000157280 Aesculus hippocastanum Species 0.000 abstract 1
- 206010030113 Oedema Diseases 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000002322 anti-exudative effect Effects 0.000 abstract 1
- 230000002668 anti-heparin effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 235000010181 horse chestnut Nutrition 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XTHPWXDJESJLNJ-UHFFFAOYSA-N sulfurochloridic acid Chemical compound OS(Cl)(=O)=O XTHPWXDJESJLNJ-UHFFFAOYSA-N 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752530954 DE2530954A1 (de) | 1975-07-11 | 1975-07-11 | Sulfatierte saponinsalze, verfahren zur herstellung und arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1492023A true GB1492023A (en) | 1977-11-16 |
Family
ID=5951226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28231/76A Expired GB1492023A (en) | 1975-07-11 | 1976-07-07 | Aescin polysulphuric acid esters |
Country Status (19)
-
1975
- 1975-07-11 DE DE19752530954 patent/DE2530954A1/de not_active Withdrawn
-
1976
- 1976-06-30 PT PT65300A patent/PT65300B/pt unknown
- 1976-07-05 FI FI761956A patent/FI761956A7/fi not_active Application Discontinuation
- 1976-07-05 BG BG033671A patent/BG27377A3/xx unknown
- 1976-07-06 CS CS764472A patent/CS193552B2/cs unknown
- 1976-07-07 GB GB28231/76A patent/GB1492023A/en not_active Expired
- 1976-07-07 SU SU762378552A patent/SU614741A3/ru active
- 1976-07-08 AU AU15731/76A patent/AU504838B2/en not_active Expired
- 1976-07-08 ZA ZA764063A patent/ZA764063B/xx unknown
- 1976-07-08 YU YU01668/76A patent/YU166876A/xx unknown
- 1976-07-09 HU HU76MA2795A patent/HU174602B/hu unknown
- 1976-07-09 CA CA256,652A patent/CA1064904A/en not_active Expired
- 1976-07-10 RO RO7686930A patent/RO70425A/ro unknown
- 1976-07-10 PL PL1976191112A patent/PL99630B1/pl unknown
- 1976-07-12 BE BE168850A patent/BE844054A/xx unknown
- 1976-07-12 PH PH18680A patent/PH12629A/en unknown
- 1976-07-12 FR FR7621312A patent/FR2316960A1/fr active Granted
- 1976-07-12 JP JP51082844A patent/JPS5236655A/ja active Granted
-
1978
- 1978-08-31 HK HK491/78A patent/HK49178A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU614741A3 (ru) | 1978-07-05 |
| PT65300B (de) | 1977-12-13 |
| AU504838B2 (en) | 1979-11-01 |
| ZA764063B (en) | 1977-07-27 |
| BG27377A3 (bg) | 1979-10-12 |
| BE844054A (fr) | 1977-01-12 |
| HK49178A (en) | 1978-09-08 |
| DE2530954A1 (de) | 1977-01-27 |
| FR2316960B1 (enrdf_load_stackoverflow) | 1979-03-02 |
| CS193552B2 (en) | 1979-10-31 |
| PH12629A (en) | 1979-07-05 |
| PT65300A (de) | 1976-07-01 |
| CA1064904A (en) | 1979-10-23 |
| HU174602B (hu) | 1980-02-28 |
| FI761956A7 (enrdf_load_stackoverflow) | 1977-01-12 |
| FR2316960A1 (fr) | 1977-02-04 |
| JPS5614117B2 (enrdf_load_stackoverflow) | 1981-04-02 |
| YU166876A (en) | 1982-05-31 |
| JPS5236655A (en) | 1977-03-22 |
| RO70425A (ro) | 1980-12-30 |
| PL99630B1 (pl) | 1978-07-31 |
| AU1573176A (en) | 1978-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |