GB1490983A - Bis((n-hydroxyalkyl)-aminoalkylthio)-alkanes and derivatives thereof - Google Patents

Bis((n-hydroxyalkyl)-aminoalkylthio)-alkanes and derivatives thereof

Info

Publication number
GB1490983A
GB1490983A GB366474A GB366474A GB1490983A GB 1490983 A GB1490983 A GB 1490983A GB 366474 A GB366474 A GB 366474A GB 366474 A GB366474 A GB 366474A GB 1490983 A GB1490983 A GB 1490983A
Authority
GB
United Kingdom
Prior art keywords
aminoalkylthio
alkanes
hydroxyalkyl
bis
jan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB366474A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Priority to GB366474A priority Critical patent/GB1490983A/en
Priority to FR7502307A priority patent/FR2258846A1/en
Priority to BE2054099A priority patent/BE824716A/en
Publication of GB1490983A publication Critical patent/GB1490983A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/42—Y being a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1490983 Bis-(aminoalkylthio)-alkanes and sulphones and sulphoxides LABORATOIRE L. LAFON 24 Jan 1975 [25 Jan 1974] 03664/74 Heading C2C Novel compounds (I) (including salts thereof) where n is 5 to 15, x is 0, 1 or 2, A is C 2-6 alkylene, B is hydroxyalkyl, dihydroxyalkyl or acyloxyalkyl and R is H, alkyl, acyl, B, sulphoalkyl or sulphonate alkyl, are made by standard methods. 1,16 - Dichloro - 2,15 - dimethyl - 3,14 - dithiahexadecane and p - (p - chlorophenylthio)- phenoxyisobutyryl chloride are also prepared. Pharmaceutical preparations useful in treating atherosclerosis contain (I) as active ingredient. Administration is orally, parenterally or topically.
GB366474A 1974-01-25 1974-01-25 Bis((n-hydroxyalkyl)-aminoalkylthio)-alkanes and derivatives thereof Expired GB1490983A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB366474A GB1490983A (en) 1974-01-25 1974-01-25 Bis((n-hydroxyalkyl)-aminoalkylthio)-alkanes and derivatives thereof
FR7502307A FR2258846A1 (en) 1974-01-25 1975-01-24 Bis((N-hydroxy alkyl)-amino alkyl thio)alkane and derivs - as agents preventing blood platelet aggregation
BE2054099A BE824716A (en) 1974-01-25 1975-01-24 BIS - ((N-HYDROXYALKYL) -AMINOALKYLTHIO) -ALKANES AND DERIVATIVES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB366474A GB1490983A (en) 1974-01-25 1974-01-25 Bis((n-hydroxyalkyl)-aminoalkylthio)-alkanes and derivatives thereof

Publications (1)

Publication Number Publication Date
GB1490983A true GB1490983A (en) 1977-11-09

Family

ID=9762611

Family Applications (1)

Application Number Title Priority Date Filing Date
GB366474A Expired GB1490983A (en) 1974-01-25 1974-01-25 Bis((n-hydroxyalkyl)-aminoalkylthio)-alkanes and derivatives thereof

Country Status (2)

Country Link
BE (1) BE824716A (en)
GB (1) GB1490983A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520602A (en) 1976-04-02 1978-08-09 Lafon Labor Esters of bis-(hydroxyalkylthio)-alkanes

Also Published As

Publication number Publication date
BE824716A (en) 1975-05-15

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Legal Events

Date Code Title Description
PS Patent sealed
746 Register noted 'licences of right' (sect. 46/1977)
PCNP Patent ceased through non-payment of renewal fee