GB1489468A - Production of l-phenylalanine - Google Patents

Production of l-phenylalanine

Info

Publication number
GB1489468A
GB1489468A GB7482/75A GB748275A GB1489468A GB 1489468 A GB1489468 A GB 1489468A GB 7482/75 A GB7482/75 A GB 7482/75A GB 748275 A GB748275 A GB 748275A GB 1489468 A GB1489468 A GB 1489468A
Authority
GB
United Kingdom
Prior art keywords
phenylalanine
lyase
ammonia
feb
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7482/75A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of GB1489468A publication Critical patent/GB1489468A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222—Phenylalanine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GB7482/75A 1974-02-22 1975-02-21 Production of l-phenylalanine Expired GB1489468A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44476374A 1974-02-22 1974-02-22

Publications (1)

Publication Number Publication Date
GB1489468A true GB1489468A (en) 1977-10-19

Family

ID=23766249

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7482/75A Expired GB1489468A (en) 1974-02-22 1975-02-21 Production of l-phenylalanine

Country Status (3)

Country Link
ES (1) ES433764A1 (el)
FR (1) FR2262110B1 (el)
GB (1) GB1489468A (el)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143560A2 (en) * 1983-10-31 1985-06-05 Genex Corporation Method for stabilizing the enzymic activity of phenylalanine ammonia lyase during L-phenylalanine production
GB2159517A (en) * 1984-05-31 1985-12-04 Erba Farmitalia Separation of phenylalanine from fermentation broths
US4574117A (en) * 1984-06-06 1986-03-04 Genex Corporation Stabilization of phenylalanine ammonia-lyase in a bioreactor using reducing agents
US4584273A (en) * 1983-10-31 1986-04-22 Genex Corporation Method for the production of phenylalanine ammonia-lyase by fermentation
US4598047A (en) * 1984-06-25 1986-07-01 Genex Corporation Phenylalanine ammonia lyase-producing microbial cells
US4636466A (en) * 1983-10-31 1987-01-13 Genex Corporation Phenylalanine ammonia lyase-producing microbial cells
US4681850A (en) * 1984-11-20 1987-07-21 Genex Corporation Phenylalanine ammonia lyase-producing microbial cells
GB2194247A (en) * 1986-08-19 1988-03-02 Allelix Inc Mutant microorganisms
US4731469A (en) * 1986-08-06 1988-03-15 Synthetech, Inc. Process for recovery and purification of L-phenylalanine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1206435A (en) * 1982-10-01 1986-06-24 Wayne E. Swann Method for the production of l-phenylalanine through the reuse of phenylalanine ammonia lyase
US4562151A (en) * 1983-09-06 1985-12-31 Monsanto Company Stabilization of L-phenylalanine ammonia-lyase enzyme

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143560A3 (en) * 1983-10-31 1987-04-29 Genex Corporation Method for stabilizing the enzymic activity of phenylalanine ammonia lyase during l-phenylalanine production
EP0143560A2 (en) * 1983-10-31 1985-06-05 Genex Corporation Method for stabilizing the enzymic activity of phenylalanine ammonia lyase during L-phenylalanine production
US4584269A (en) * 1983-10-31 1986-04-22 Genex Corporation Method for stabilizing the enzymatic activity of phenylalanine ammonia lyase during L-phenylalanine production
US4584273A (en) * 1983-10-31 1986-04-22 Genex Corporation Method for the production of phenylalanine ammonia-lyase by fermentation
US4636466A (en) * 1983-10-31 1987-01-13 Genex Corporation Phenylalanine ammonia lyase-producing microbial cells
GB2159517A (en) * 1984-05-31 1985-12-04 Erba Farmitalia Separation of phenylalanine from fermentation broths
DE3519074A1 (de) * 1984-05-31 1985-12-05 Farmitalia Carlo Erba S.p.A., Mailand/Milano Verfahren zur extraktion von phenylalanin aus fluessigkeiten der biokonversion
US4668821A (en) * 1984-05-31 1987-05-26 Farmitalia Carlo Erba S.P.A. Method for extracting phenylalanine from broths of bioconversion
US4574117A (en) * 1984-06-06 1986-03-04 Genex Corporation Stabilization of phenylalanine ammonia-lyase in a bioreactor using reducing agents
US4598047A (en) * 1984-06-25 1986-07-01 Genex Corporation Phenylalanine ammonia lyase-producing microbial cells
US4681850A (en) * 1984-11-20 1987-07-21 Genex Corporation Phenylalanine ammonia lyase-producing microbial cells
US4731469A (en) * 1986-08-06 1988-03-15 Synthetech, Inc. Process for recovery and purification of L-phenylalanine
GB2194247A (en) * 1986-08-19 1988-03-02 Allelix Inc Mutant microorganisms

Also Published As

Publication number Publication date
ES433764A1 (es) 1976-12-01
FR2262110B1 (el) 1978-06-23
FR2262110A1 (el) 1975-09-19

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee