GB1488259A - Method for increasing the bioavailability of digitalis cardiac glycosides - Google Patents

Method for increasing the bioavailability of digitalis cardiac glycosides

Info

Publication number
GB1488259A
GB1488259A GB53096/74A GB5309674A GB1488259A GB 1488259 A GB1488259 A GB 1488259A GB 53096/74 A GB53096/74 A GB 53096/74A GB 5309674 A GB5309674 A GB 5309674A GB 1488259 A GB1488259 A GB 1488259A
Authority
GB
United Kingdom
Prior art keywords
glycoside
digoxin
digitalis
digitoxin
acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB53096/74A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Priority to PH17005A priority Critical patent/PH13597A/en
Publication of GB1488259A publication Critical patent/GB1488259A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1488259 Digitalis glycoside preparations R P SCHERER CORP 9 Dec 1974 [28 Aug 1974] 53096/74 Heading A5B A digitalis cardiac glycoside preparation is produced by (a) determining a weight of glycoside suitable for oral administration to a human patient in tablet form, (b) calculating 50 to 80% of the first amount, (e) dissolving the calculated amount of glycoside and (d) encapsulating the solution in soft elastic gelatin capsules. Glycosides specified are digoxin, digitoxin, digitalin, lanatoside C, acetyl-digoxin, acetyl-digitoxin and methyl digoxin. The solution preferably includes liquid polyethylene glycol mixed with aqueous ethanol, propylene glycol and/or glycerol.
GB53096/74A 1974-08-28 1974-12-09 Method for increasing the bioavailability of digitalis cardiac glycosides Expired GB1488259A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PH17005A PH13597A (en) 1974-08-28 1975-04-02 Method for increasing the bioabailability of digitalis cardiac glycosides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50123874A 1974-08-28 1974-08-28

Publications (1)

Publication Number Publication Date
GB1488259A true GB1488259A (en) 1977-10-12

Family

ID=23992693

Family Applications (1)

Application Number Title Priority Date Filing Date
GB53096/74A Expired GB1488259A (en) 1974-08-28 1974-12-09 Method for increasing the bioavailability of digitalis cardiac glycosides

Country Status (7)

Country Link
AU (1) AU7681074A (en)
BE (1) BE832794A (en)
DE (1) DE2508504B2 (en)
FR (1) FR2282863A1 (en)
GB (1) GB1488259A (en)
NL (1) NL7505600A (en)
ZA (1) ZA751051B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2623072C2 (en) * 2015-10-01 2017-06-21 Владимир Андреевич Болсуновский Method for producing digoxin preparation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3122585A1 (en) 2021-05-04 2022-11-11 Universite Claude Bernard Lyon 1 Mesoporous solid to regulate humidity in enclosed spaces

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2298122A (en) * 1941-01-27 1942-10-06 United Drug Company Digitalis capsule
GB1405088A (en) * 1971-06-03 1975-09-03 Mundipharma Ag Slow release formulation
GB1481411A (en) * 1973-07-20 1977-07-27 Scherer Ltd R Pharmaceutical compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2623072C2 (en) * 2015-10-01 2017-06-21 Владимир Андреевич Болсуновский Method for producing digoxin preparation

Also Published As

Publication number Publication date
BE832794A (en) 1976-02-27
ZA751051B (en) 1976-01-28
NL7505600A (en) 1976-03-02
FR2282863B1 (en) 1978-08-04
AU7681074A (en) 1976-06-24
DE2508504A1 (en) 1976-03-11
DE2508504B2 (en) 1978-04-13
FR2282863A1 (en) 1976-03-26

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee