GB1488259A - Method for increasing the bioavailability of digitalis cardiac glycosides - Google Patents
Method for increasing the bioavailability of digitalis cardiac glycosidesInfo
- Publication number
- GB1488259A GB1488259A GB53096/74A GB5309674A GB1488259A GB 1488259 A GB1488259 A GB 1488259A GB 53096/74 A GB53096/74 A GB 53096/74A GB 5309674 A GB5309674 A GB 5309674A GB 1488259 A GB1488259 A GB 1488259A
- Authority
- GB
- United Kingdom
- Prior art keywords
- glycoside
- digoxin
- digitalis
- digitoxin
- acetyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1488259 Digitalis glycoside preparations R P SCHERER CORP 9 Dec 1974 [28 Aug 1974] 53096/74 Heading A5B A digitalis cardiac glycoside preparation is produced by (a) determining a weight of glycoside suitable for oral administration to a human patient in tablet form, (b) calculating 50 to 80% of the first amount, (e) dissolving the calculated amount of glycoside and (d) encapsulating the solution in soft elastic gelatin capsules. Glycosides specified are digoxin, digitoxin, digitalin, lanatoside C, acetyl-digoxin, acetyl-digitoxin and methyl digoxin. The solution preferably includes liquid polyethylene glycol mixed with aqueous ethanol, propylene glycol and/or glycerol.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PH17005A PH13597A (en) | 1974-08-28 | 1975-04-02 | Method for increasing the bioabailability of digitalis cardiac glycosides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50123874A | 1974-08-28 | 1974-08-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1488259A true GB1488259A (en) | 1977-10-12 |
Family
ID=23992693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB53096/74A Expired GB1488259A (en) | 1974-08-28 | 1974-12-09 | Method for increasing the bioavailability of digitalis cardiac glycosides |
Country Status (7)
Country | Link |
---|---|
AU (1) | AU7681074A (en) |
BE (1) | BE832794A (en) |
DE (1) | DE2508504B2 (en) |
FR (1) | FR2282863A1 (en) |
GB (1) | GB1488259A (en) |
NL (1) | NL7505600A (en) |
ZA (1) | ZA751051B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2623072C2 (en) * | 2015-10-01 | 2017-06-21 | Владимир Андреевич Болсуновский | Method for producing digoxin preparation |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3122585A1 (en) | 2021-05-04 | 2022-11-11 | Universite Claude Bernard Lyon 1 | Mesoporous solid to regulate humidity in enclosed spaces |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2298122A (en) * | 1941-01-27 | 1942-10-06 | United Drug Company | Digitalis capsule |
GB1405088A (en) * | 1971-06-03 | 1975-09-03 | Mundipharma Ag | Slow release formulation |
GB1481411A (en) * | 1973-07-20 | 1977-07-27 | Scherer Ltd R | Pharmaceutical compositions |
-
1974
- 1974-12-09 GB GB53096/74A patent/GB1488259A/en not_active Expired
- 1974-12-24 AU AU76810/74A patent/AU7681074A/en not_active Expired
-
1975
- 1975-02-19 ZA ZA00751051A patent/ZA751051B/en unknown
- 1975-02-27 DE DE2508504A patent/DE2508504B2/en not_active Ceased
- 1975-04-11 FR FR7511468A patent/FR2282863A1/en active Granted
- 1975-05-13 NL NL7505600A patent/NL7505600A/en not_active Application Discontinuation
- 1975-08-27 BE BE159505A patent/BE832794A/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2623072C2 (en) * | 2015-10-01 | 2017-06-21 | Владимир Андреевич Болсуновский | Method for producing digoxin preparation |
Also Published As
Publication number | Publication date |
---|---|
BE832794A (en) | 1976-02-27 |
ZA751051B (en) | 1976-01-28 |
NL7505600A (en) | 1976-03-02 |
FR2282863B1 (en) | 1978-08-04 |
AU7681074A (en) | 1976-06-24 |
DE2508504A1 (en) | 1976-03-11 |
DE2508504B2 (en) | 1978-04-13 |
FR2282863A1 (en) | 1976-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |