GB1487369A - Cephalosporins - Google Patents

Cephalosporins

Info

Publication number
GB1487369A
GB1487369A GB53116/74A GB5311674A GB1487369A GB 1487369 A GB1487369 A GB 1487369A GB 53116/74 A GB53116/74 A GB 53116/74A GB 5311674 A GB5311674 A GB 5311674A GB 1487369 A GB1487369 A GB 1487369A
Authority
GB
United Kingdom
Prior art keywords
alkyl
phenyl
halo
dec
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB53116/74A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/468,716 external-priority patent/US3960850A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB1487369A publication Critical patent/GB1487369A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Fodder In General (AREA)

Abstract

1487369 Silylated cephalosporins E R SQUIBB & SONS Inc 9 Dec 1974 [28 Dec 1973 10 May 1974] 53116/74 Heading C3S [Also in Division C2] Novel compounds I (R 1 is H, 1-8C alkyl, phenyl or phenyl-1-8C alkyl-optionally substituted by halo, 1-8C alkyl or alkoxy, OH or COOH- or R 1 is 5-6- membered heterocyclyl optionally substituted by halo, 1-8C alkyl or alkoxy or phenyl; R 2 is 1-8C alkyl; R 3 is tri(1-8C alkyl)silyl and R 4 is H, acetoxy, a quaternary ammonium radical, 1-8C alkylthio, heterocyclylthio or a nitrogenlinked radical of an amine) are prepared by reaction of a compound II or an acylating derivative thereof with a compound III
GB53116/74A 1973-12-28 1974-12-09 Cephalosporins Expired GB1487369A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42922573A 1973-12-28 1973-12-28
US05/468,716 US3960850A (en) 1974-05-10 1974-05-10 3-Heterothio derivatives of [(alkoxycarbonyl)oxyacetyl]cephalosporins

Publications (1)

Publication Number Publication Date
GB1487369A true GB1487369A (en) 1977-09-28

Family

ID=27028093

Family Applications (1)

Application Number Title Priority Date Filing Date
GB53116/74A Expired GB1487369A (en) 1973-12-28 1974-12-09 Cephalosporins

Country Status (4)

Country Link
JP (1) JPS5096592A (en)
DE (1) DE2461505A1 (en)
FR (1) FR2255912B1 (en)
GB (1) GB1487369A (en)

Also Published As

Publication number Publication date
JPS5096592A (en) 1975-07-31
DE2461505A1 (en) 1975-07-10
FR2255912A1 (en) 1975-07-25
FR2255912B1 (en) 1978-07-21

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee