GB1476026A - Acetylsalicylic acid derivatives their preparation and compo sitions containing them - Google Patents

Acetylsalicylic acid derivatives their preparation and compo sitions containing them

Info

Publication number
GB1476026A
GB1476026A GB3823075A GB3823075A GB1476026A GB 1476026 A GB1476026 A GB 1476026A GB 3823075 A GB3823075 A GB 3823075A GB 3823075 A GB3823075 A GB 3823075A GB 1476026 A GB1476026 A GB 1476026A
Authority
GB
United Kingdom
Prior art keywords
acetylsalicylate
amino
carbon atoms
acid derivatives
acetylsalicylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3823075A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7431400A external-priority patent/FR2285141A1/en
Priority claimed from FR7520099A external-priority patent/FR2315279A1/en
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Publication of GB1476026A publication Critical patent/GB1476026A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1476026 Acetylsalicylic acid derivatives RHONE-POULENC INDUSTRIES 17 Sept 1975 [17 Sept 1974 26 June 1975] 38230/75 Heading C2C Acetylsalicyclic acid derivatives of the general formula in which R 1 and R 2 , which may be identical or different, represent hydrogen or alkyl of 1 to 4 carbon atoms which is unsubstituted or substituted by hydroxyl, R 3 and R 4 , which may be identical or different, represent hydrogen or alkyl of 1 to 4 carbon atoms or, with the carbon atom to which they are bonded, together form a saturated ring with 5 or 6 ring atoms, or one of the symbols R 1 and R 2 , together with one of the symbols R 3 and R 4 and the nitrogen and carbon atoms to which they are respectively bonded, form a nitrogen-containing heterocyclic ring with 5 or 6 ring atoms, and R 5 and R 6 , which may be identical or different, represent hydrogen or alkyl of 1 to 4 carbon atoms which is unsubstituted or substituted by hydroxyl, and n is zero or 1, are prepared by reacting a compound of the general formula with acetylsalicylic acid in an organic solvent or in water and isolating the salt obtained. The compounds claimed per se are 2-amino-2- methy - propionamide acetylsalicylate; 2- methyl - 2 - methyl - amino - propionamide acetylsalicylate; aminoacetamide acetylsalicylate; 1 - amino - cyclohexanecarboxamide acetylsalicylate; 2 - dimethylamino - 2 - methylpropionamide acetylsalicylate; 2 - carbamoylpiperidine acetylsalicylate; 2 - amino -2- methyl - butyramide acetylsalicylate; 2- amino - 2,4 - dimethylpentamide acetylsalicylate. The compounds have pharmaceutical properties.
GB3823075A 1974-09-17 1975-09-17 Acetylsalicylic acid derivatives their preparation and compo sitions containing them Expired GB1476026A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7431400A FR2285141A1 (en) 1974-09-17 1974-09-17 Water-soluble aminoalkanoamide salts of acetylsalicylic acid - with anti-inflammatory, analgesic and antipyretic activity (BE-16.3.76)
FR7520099A FR2315279A1 (en) 1975-06-26 1975-06-26 Water-soluble aminoalkanoamide salts of acetylsalicylic acid - with anti-inflammatory, analgesic and antipyretic activity (BE-16.3.76)

Publications (1)

Publication Number Publication Date
GB1476026A true GB1476026A (en) 1977-06-10

Family

ID=26218517

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3823075A Expired GB1476026A (en) 1974-09-17 1975-09-17 Acetylsalicylic acid derivatives their preparation and compo sitions containing them

Country Status (13)

Country Link
JP (1) JPS5161615A (en)
AT (1) AT339886B (en)
AU (1) AU8484975A (en)
CH (1) CH593234A5 (en)
DE (1) DE2541475A1 (en)
ES (1) ES441029A1 (en)
FI (1) FI752589A (en)
GB (1) GB1476026A (en)
HU (1) HU172524B (en)
IL (1) IL48108A0 (en)
LU (1) LU73412A1 (en)
NL (1) NL7510622A (en)
NO (1) NO753158L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
JPS5742680A (en) * 1980-08-29 1982-03-10 Bago Sa Labor Novel ester of substituted benzoic acid and manufacture

Also Published As

Publication number Publication date
FI752589A (en) 1976-03-18
HU172524B (en) 1978-09-28
JPS5161615A (en) 1976-05-28
AT339886B (en) 1977-11-10
NL7510622A (en) 1976-03-19
DE2541475A1 (en) 1976-03-25
ES441029A1 (en) 1977-03-01
ATA713675A (en) 1977-03-15
NO753158L (en) 1976-03-18
LU73412A1 (en) 1976-08-13
IL48108A0 (en) 1975-11-25
AU8484975A (en) 1977-03-24
CH593234A5 (en) 1977-11-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee