GB1472652A - Piperazinyl esters of n-quinelylanthranilic acid - Google Patents
Piperazinyl esters of n-quinelylanthranilic acidInfo
- Publication number
- GB1472652A GB1472652A GB2109074A GB2109074A GB1472652A GB 1472652 A GB1472652 A GB 1472652A GB 2109074 A GB2109074 A GB 2109074A GB 2109074 A GB2109074 A GB 2109074A GB 1472652 A GB1472652 A GB 1472652A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- acid
- piperazinyl
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
1472652 Piperazinyl esters of N-quinolylanthranilic acid ROUSSEL UCLAF 13 May 1974 [11 May 1973] 21090/74 Heading C2C Novel compounds of formula I [in which n is 0 or an integer from 1 to 5, Y is located at the 7- or 8-position of the quinoline ring system and represents a halogen atom or a trifluoromethyl, trifluoromethylthio or trifluoromethoxy group, and Z which is located at any position on the benzene ring represents a hydrogen atom, a halogen atom, an alkyl group having from 1 to 4 carbon atoms or an alkoxy group having from 1 to 4 carbon atoms] and non-toxic acid addition salts thereof are prepared either by reacting a functional derivative of an acid of formula II with a compound of formula III or by reacting a compound of formula IV with a compound of formula III. Pharmaceutical compositions in conventional forms for bucal, rectal or parenteral administration having analgesic and anti-inflammatory activity comprise an above novel compound and a carrier or diluent.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7317069A FR2228482B1 (en) | 1973-05-11 | 1973-05-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1472652A true GB1472652A (en) | 1977-05-04 |
Family
ID=9119165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2109074A Expired GB1472652A (en) | 1973-05-11 | 1974-05-13 | Piperazinyl esters of n-quinelylanthranilic acid |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5014688A (en) |
| AU (1) | AU6876774A (en) |
| BE (1) | BE814792A (en) |
| CA (1) | CA1106376A (en) |
| CH (1) | CH585225A5 (en) |
| DE (1) | DE2422848A1 (en) |
| ES (1) | ES425974A1 (en) |
| FR (1) | FR2228482B1 (en) |
| GB (1) | GB1472652A (en) |
| IE (1) | IE40385B1 (en) |
| IL (1) | IL44708A0 (en) |
| LU (1) | LU70024A1 (en) |
| NL (1) | NL7406229A (en) |
| ZA (1) | ZA742658B (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR7870M (en) * | 1968-11-08 | 1970-04-27 | ||
| BE754587A (en) * | 1969-08-08 | 1971-02-08 | Upjohn Co | NEW P- (TRIHALOMETHYLQUINOLYLAMINO) BENZAMIDES AND THEIR PREPARATION PROCESS |
| BE785973A (en) * | 1971-07-09 | 1973-01-08 | Roussel Uclaf | NEW 4-AMINO QUINOLEINES AND PREPARATION PROCESS |
-
1973
- 1973-05-11 FR FR7317069A patent/FR2228482B1/fr not_active Expired
-
1974
- 1974-04-24 IL IL44708A patent/IL44708A0/en unknown
- 1974-04-26 ZA ZA00742658A patent/ZA742658B/en unknown
- 1974-05-02 JP JP49048850A patent/JPS5014688A/ja active Pending
- 1974-05-04 ES ES425974A patent/ES425974A1/en not_active Expired
- 1974-05-08 CA CA199,329A patent/CA1106376A/en not_active Expired
- 1974-05-09 LU LU70024A patent/LU70024A1/xx unknown
- 1974-05-09 AU AU68767/74A patent/AU6876774A/en not_active Expired
- 1974-05-09 BE BE144130A patent/BE814792A/en unknown
- 1974-05-09 NL NL7406229A patent/NL7406229A/xx not_active Application Discontinuation
- 1974-05-10 IE IE1002/74A patent/IE40385B1/en unknown
- 1974-05-10 CH CH646174A patent/CH585225A5/xx not_active IP Right Cessation
- 1974-05-10 DE DE2422848A patent/DE2422848A1/en not_active Ceased
- 1974-05-13 GB GB2109074A patent/GB1472652A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA742658B (en) | 1975-05-28 |
| CA1106376A (en) | 1981-08-04 |
| IL44708A0 (en) | 1974-06-30 |
| FR2228482B1 (en) | 1976-05-14 |
| IE40385L (en) | 1974-11-11 |
| IE40385B1 (en) | 1979-05-23 |
| DE2422848A1 (en) | 1974-11-28 |
| FR2228482A1 (en) | 1974-12-06 |
| NL7406229A (en) | 1974-11-13 |
| ES425974A1 (en) | 1976-07-01 |
| LU70024A1 (en) | 1974-11-28 |
| JPS5014688A (en) | 1975-02-15 |
| CH585225A5 (en) | 1977-02-28 |
| BE814792A (en) | 1974-11-12 |
| AU6876774A (en) | 1975-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 414F | Notice of opposition given (sect. 14/1949) | ||
| 414A | Case decided by the comptroller ** specification amended (sect. 14/1949) | ||
| SPA | Amended specification published | ||
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |