GB1463270A - Preparation of a semi-synthetic penicillin - Google Patents
Preparation of a semi-synthetic penicillinInfo
- Publication number
- GB1463270A GB1463270A GB4922275A GB4922275A GB1463270A GB 1463270 A GB1463270 A GB 1463270A GB 4922275 A GB4922275 A GB 4922275A GB 4922275 A GB4922275 A GB 4922275A GB 1463270 A GB1463270 A GB 1463270A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- dimethylpenam
- carboxylic acid
- semi
- aminophenylacetamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930182555 Penicillin Natural products 0.000 title abstract 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title abstract 2
- 229940049954 penicillin Drugs 0.000 title abstract 2
- AVKUERGKIZMTKX-FOQMGDCRSA-N (5r)-6-[(2-amino-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Chemical compound C1([C@H]2SC(C(N2C1=O)C(O)=O)(C)C)NC(=O)C(N)C1=CC=CC=C1 AVKUERGKIZMTKX-FOQMGDCRSA-N 0.000 abstract 2
- MRWCZVGUIZPARU-FOQMGDCRSA-N (5R)-6-[(2-hydrazinyl-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Chemical compound N(N)C(C(=O)NC1[C@@H]2N(C(C(S2)(C)C)C(=O)O)C1=O)C1=CC=CC=C1 MRWCZVGUIZPARU-FOQMGDCRSA-N 0.000 abstract 1
- 101100533558 Mus musculus Sipa1 gene Proteins 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
- C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3018874 | 1974-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1463270A true GB1463270A (en) | 1977-02-02 |
Family
ID=11229285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4922275A Expired GB1463270A (en) | 1974-12-05 | 1975-12-01 | Preparation of a semi-synthetic penicillin |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5182287A (enExample) |
| DE (1) | DE2554567A1 (enExample) |
| ES (1) | ES443190A1 (enExample) |
| FR (1) | FR2293434A1 (enExample) |
| GB (1) | GB1463270A (enExample) |
| NL (1) | NL7513996A (enExample) |
-
1975
- 1975-12-01 GB GB4922275A patent/GB1463270A/en not_active Expired
- 1975-12-01 NL NL7513996A patent/NL7513996A/xx unknown
- 1975-12-04 JP JP14341675A patent/JPS5182287A/ja active Pending
- 1975-12-04 DE DE19752554567 patent/DE2554567A1/de active Pending
- 1975-12-04 FR FR7537107A patent/FR2293434A1/fr active Granted
- 1975-12-04 ES ES443190A patent/ES443190A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2293434A1 (fr) | 1976-07-02 |
| NL7513996A (nl) | 1976-06-09 |
| DE2554567A1 (de) | 1976-06-10 |
| FR2293434B1 (enExample) | 1978-05-12 |
| ES443190A1 (es) | 1977-08-16 |
| JPS5182287A (en) | 1976-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |