GB1462958A - Biodegradable implantable drug delivery device and process for preparing and using the same - Google Patents
Biodegradable implantable drug delivery device and process for preparing and using the sameInfo
- Publication number
- GB1462958A GB1462958A GB2136174A GB2136174A GB1462958A GB 1462958 A GB1462958 A GB 1462958A GB 2136174 A GB2136174 A GB 2136174A GB 2136174 A GB2136174 A GB 2136174A GB 1462958 A GB1462958 A GB 1462958A
- Authority
- GB
- United Kingdom
- Prior art keywords
- implanted
- preparing
- same
- delivery device
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/2045—Polyamides; Polyaminoacids, e.g. polylysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
Abstract
1462958 Controlled release devices ARTHUR D LITTLE Inc 14 May 1974 [17 May 1973] 21361/74 Heading A5B An implant device for the controllable release of a biologically active substance or a diagnostic agent into a living host into which it is to be implanted comprises a biodegradable matrix structure formed from a substantially non-toxic polymer of an alpha-amino acid having the substance which is to be controllably released physically distributed therethrough. The implants may be for example, in the form of films, ribbons rods or fibres and may be implanted in or near an organ of the body, or they may be implanted subdermally They may also be administered as uterine or vaginal inserts.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36118273A | 1973-05-17 | 1973-05-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1462958A true GB1462958A (en) | 1977-01-26 |
Family
ID=23420985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2136174A Expired GB1462958A (en) | 1973-05-17 | 1974-05-14 | Biodegradable implantable drug delivery device and process for preparing and using the same |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPS5040718A (en) |
CA (1) | CA1045977A (en) |
CH (1) | CH591255A5 (en) |
DE (1) | DE2424169A1 (en) |
FR (1) | FR2287242A1 (en) |
GB (1) | GB1462958A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2295316A (en) * | 1994-11-25 | 1996-05-29 | William Leslie Porter | Bolus for supplying biologically beneficial substances to ruminant animals |
US7833548B2 (en) | 2002-06-18 | 2010-11-16 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
US10390702B2 (en) | 2011-12-30 | 2019-08-27 | Kibur Medical, Inc. | Implantable devices and methods for the evaluation of active agents |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5423050B2 (en) * | 1972-04-28 | 1979-08-10 | ||
JPS4964542A (en) * | 1972-10-25 | 1974-06-22 | ||
JPS52137559A (en) * | 1976-05-12 | 1977-11-17 | Brother Ind Ltd | Coupling method for component parts |
WO1978000011A1 (en) * | 1977-06-07 | 1978-12-21 | Garching Instrumente | Form of implant medicament and preparation process |
PH25589A (en) * | 1979-09-12 | 1991-08-08 | Lilly Co Eli | Device for drug celivery to ruminants |
GB2077586A (en) * | 1980-06-12 | 1981-12-23 | Standard Telephones Cables Ltd | Sustained-release device |
JPS57128621A (en) * | 1981-01-30 | 1982-08-10 | Japan Atom Energy Res Inst | Preparation of prolonged release type composite |
JPS58144314A (en) * | 1982-02-19 | 1983-08-27 | Japan Atom Energy Res Inst | Preparation of combined substance having prolonged effect |
JPS58154509A (en) * | 1982-03-10 | 1983-09-14 | Japan Atom Energy Res Inst | Preparation of slow-releasing composite |
JPS58192817A (en) * | 1982-05-06 | 1983-11-10 | Nippon Soda Co Ltd | Production of stick-like drug preparation |
US5248700A (en) * | 1982-05-14 | 1993-09-28 | Akzo Nv | Active agent containing solid structures for prolonged release of active agents |
JPS58213708A (en) * | 1982-06-03 | 1983-12-12 | Mitsui Toatsu Chem Inc | Preparation of molded bar drug having prolonged effect |
JPS58225008A (en) * | 1982-06-25 | 1983-12-27 | Japan Atom Energy Res Inst | Preparation of prolonged action compounded substance |
JPS5968209A (en) * | 1982-10-13 | 1984-04-18 | Mikuni Plast Kk | Manufacture of joint pipe |
JPS59135053A (en) * | 1983-01-20 | 1984-08-03 | 日本特殊陶業株式会社 | Liquid medicine impregnated fibrous ceramics |
JPS59139318A (en) * | 1983-01-31 | 1984-08-10 | Mitsui Toatsu Chem Inc | Production of filmlike or sheetlike molded pharmaceutical material |
WO1985000372A1 (en) * | 1983-07-01 | 1985-01-31 | Battelle Memorial Institute | Biodegradable polypeptide and utilization thereof for the progressive release of drugs |
GB2146531B (en) * | 1983-09-15 | 1987-04-29 | Stc Plc | Controlled release system |
GB2146524B (en) * | 1983-09-15 | 1987-04-08 | Stc Plc | Differential release system for aqueous media |
JPS60237015A (en) * | 1984-05-11 | 1985-11-25 | Koken:Kk | Sustained release drug |
DE3671375D1 (en) * | 1985-02-19 | 1990-06-28 | Dow Chemical Co | HARD TISSUE PROSTHESIS AND METHOD FOR THEIR PRODUCTION. |
DE3533369A1 (en) * | 1985-09-19 | 1987-03-19 | Alois Prof Dr Med Bloemer | ANTIBIOTIC CONTAINER AND ITS USE AS SURGICAL PLASTIC MATERIAL |
CH667874A5 (en) * | 1985-12-19 | 1988-11-15 | Battelle Memorial Institute | BIODEGRADABLE SYNTHETIC POLYPEPTIDE AND ITS USE FOR THE PREPARATION OF MEDICAMENTS. |
JPS62247555A (en) * | 1986-04-18 | 1987-10-28 | Ibiden Co Ltd | Pin grid array package substrate |
JPS62247554A (en) * | 1986-04-18 | 1987-10-28 | Ibiden Co Ltd | Pin grid array package substrate |
DE3745075C2 (en) * | 1986-08-18 | 1997-04-30 | Emisphere Tech Inc | Therapeutic agent encapsulated in proteinoid microspheres |
USRE35862E (en) * | 1986-08-18 | 1998-07-28 | Emisphere Technologies, Inc. | Delivery systems for pharmacological agents encapsulated with proteinoids |
WO1988001213A1 (en) * | 1986-08-18 | 1988-02-25 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents |
AU606383B2 (en) * | 1987-03-06 | 1991-02-07 | Research Triangle Institute | Polymer blends for selective biodegradability |
FR2618329B1 (en) * | 1987-07-22 | 1997-03-28 | Dow Corning Sa | METHOD OF MANUFACTURING A RING CAPABLE OF ENSURING THE RELEASE OF A THERAPEUTIC AGENT, AND RING MANUFACTURED BY THIS METHOD |
US4894231A (en) * | 1987-07-28 | 1990-01-16 | Biomeasure, Inc. | Therapeutic agent delivery system |
DE3832162A1 (en) * | 1988-09-22 | 1990-04-12 | Lohmann Therapie Syst Lts | METHOD FOR THE PRODUCTION OF COLLAGEN FOAMS IN THE FORM OF ENDLESS TAPES AND USE IN MEDICINE, COSMETICS AND HYGIENE |
US4976968A (en) * | 1989-02-24 | 1990-12-11 | Clinical Technologies Associates, Inc. | Anhydrous delivery systems for pharmacological agents |
US4983402A (en) * | 1989-02-24 | 1991-01-08 | Clinical Technologies Associates, Inc. | Orally administerable ANF |
US5443841A (en) * | 1992-06-15 | 1995-08-22 | Emisphere Technologies, Inc. | Proteinoid microspheres and methods for preparation and use thereof |
US5578323A (en) * | 1992-06-15 | 1996-11-26 | Emisphere Technologies, Inc. | Proteinoid carriers and methods for preparation and use thereof |
US5447728A (en) | 1992-06-15 | 1995-09-05 | Emisphere Technologies, Inc. | Desferrioxamine oral delivery system |
US6221367B1 (en) | 1992-06-15 | 2001-04-24 | Emisphere Technologies, Inc. | Active agent transport systems |
US6331318B1 (en) | 1994-09-30 | 2001-12-18 | Emisphere Technologies Inc. | Carbon-substituted diketopiperazine delivery systems |
US5693338A (en) | 1994-09-29 | 1997-12-02 | Emisphere Technologies, Inc. | Diketopiperazine-based delivery systems |
US5629020A (en) | 1994-04-22 | 1997-05-13 | Emisphere Technologies, Inc. | Modified amino acids for drug delivery |
US6099856A (en) | 1992-06-15 | 2000-08-08 | Emisphere Technologies, Inc. | Active agent transport systems |
US5714167A (en) | 1992-06-15 | 1998-02-03 | Emisphere Technologies, Inc. | Active agent transport systems |
JPH04163879A (en) * | 1990-10-26 | 1992-06-09 | Mitsumi Electric Co Ltd | Contact pin fixing method |
US5326568A (en) * | 1991-05-03 | 1994-07-05 | Giampapa Vincent C | Method of tissue-specific delivery |
US5792451A (en) | 1994-03-02 | 1998-08-11 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
US5811127A (en) | 1992-06-15 | 1998-09-22 | Emisphere Technologies, Inc. | Desferrioxamine oral delivery system |
US5401516A (en) * | 1992-12-21 | 1995-03-28 | Emisphere Technologies, Inc. | Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof |
US5643957A (en) | 1993-04-22 | 1997-07-01 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5958457A (en) | 1993-04-22 | 1999-09-28 | Emisphere Technologies, Inc. | Compositions for the delivery of antigens |
US5709861A (en) | 1993-04-22 | 1998-01-20 | Emisphere Technologies, Inc. | Compositions for the delivery of antigens |
DE69428040T2 (en) | 1993-04-22 | 2002-05-29 | Emisphere Technologies, Inc. | ORAL PHARMACEUTICAL FORM |
US6001347A (en) | 1995-03-31 | 1999-12-14 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5965121A (en) | 1995-03-31 | 1999-10-12 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5989539A (en) | 1995-03-31 | 1999-11-23 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
CN1151836C (en) | 1995-03-31 | 2004-06-02 | 艾米斯菲尔技术有限公司 | Compound and compositions for delivering active agents |
US5650386A (en) | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
US5866536A (en) | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5667806A (en) | 1995-06-07 | 1997-09-16 | Emisphere Technologies, Inc. | Spray drying method and apparatus |
US6051258A (en) | 1995-06-07 | 2000-04-18 | Emisphere Technologies, Inc. | Proteinoid emulsions and methods for preparation and use thereof |
US5750147A (en) | 1995-06-07 | 1998-05-12 | Emisphere Technologies, Inc. | Method of solubilizing and encapsulating itraconazole |
DE19608423A1 (en) * | 1996-03-05 | 1997-09-11 | Merck Patent Gmbh | Phased drug delivery implants |
EP0904065A4 (en) | 1996-06-14 | 2000-06-14 | Emisphere Tech Inc | Microencapsulated fragrances and method for preparation |
US5939381A (en) | 1997-02-07 | 1999-08-17 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5990166A (en) | 1997-02-07 | 1999-11-23 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5876710A (en) | 1997-02-07 | 1999-03-02 | Emisphere Technologies Inc. | Compounds and compositions for delivering active agents |
US5879681A (en) | 1997-02-07 | 1999-03-09 | Emisphere Technolgies Inc. | Compounds and compositions for delivering active agents |
US6358504B1 (en) | 1997-02-07 | 2002-03-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5863944A (en) | 1997-04-30 | 1999-01-26 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
-
1974
- 1974-05-10 CA CA199,552A patent/CA1045977A/en not_active Expired
- 1974-05-14 GB GB2136174A patent/GB1462958A/en not_active Expired
- 1974-05-16 CH CH674474A patent/CH591255A5/xx not_active IP Right Cessation
- 1974-05-17 DE DE19742424169 patent/DE2424169A1/en not_active Withdrawn
- 1974-05-17 JP JP5459574A patent/JPS5040718A/ja active Pending
- 1974-10-11 FR FR7434307A patent/FR2287242A1/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2295316A (en) * | 1994-11-25 | 1996-05-29 | William Leslie Porter | Bolus for supplying biologically beneficial substances to ruminant animals |
GB2295316B (en) * | 1994-11-25 | 1997-09-10 | William Leslie Porter | Bolus for supplying biologically beneficial substances to ruminant animals |
US7833548B2 (en) | 2002-06-18 | 2010-11-16 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
US10390702B2 (en) | 2011-12-30 | 2019-08-27 | Kibur Medical, Inc. | Implantable devices and methods for the evaluation of active agents |
Also Published As
Publication number | Publication date |
---|---|
CA1045977A (en) | 1979-01-09 |
FR2287242B1 (en) | 1981-06-12 |
JPS5040718A (en) | 1975-04-14 |
FR2287242A1 (en) | 1976-05-07 |
DE2424169A1 (en) | 1974-12-05 |
CH591255A5 (en) | 1977-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |