GB1462676A - Substituted esters of n-4-quinolyl-anthranilic acids - Google Patents
Substituted esters of n-4-quinolyl-anthranilic acidsInfo
- Publication number
- GB1462676A GB1462676A GB2629474A GB2629474A GB1462676A GB 1462676 A GB1462676 A GB 1462676A GB 2629474 A GB2629474 A GB 2629474A GB 2629474 A GB2629474 A GB 2629474A GB 1462676 A GB1462676 A GB 1462676A
- Authority
- GB
- United Kingdom
- Prior art keywords
- quinolyl
- formula
- acid
- june
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 4
- 150000002148 esters Chemical class 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- VAYWXCMEIWUYBK-UHFFFAOYSA-N 2-(quinolin-4-ylamino)benzoic acid Chemical compound OC(=O)C1=CC=CC=C1NC1=CC=NC2=CC=CC=C12 VAYWXCMEIWUYBK-UHFFFAOYSA-N 0.000 abstract 1
- UKNRVEVYWIFLKV-UHFFFAOYSA-N 2-[[8-(trifluoromethyl)quinolin-4-yl]amino]benzoyl chloride Chemical compound FC(C=1C=CC=C2C(=CC=NC=12)NC=1C(C(=O)Cl)=CC=CC=1)(F)F UKNRVEVYWIFLKV-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 125000004953 trihalomethyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7321434A FR2233059B1 (en, 2012) | 1973-06-13 | 1973-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1462676A true GB1462676A (en) | 1977-01-26 |
Family
ID=9120866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2629474A Expired GB1462676A (en) | 1973-06-13 | 1974-06-13 | Substituted esters of n-4-quinolyl-anthranilic acids |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3944555A (en, 2012) |
| JP (1) | JPS5032185A (en, 2012) |
| BE (1) | BE816175A (en, 2012) |
| CA (1) | CA1045140A (en, 2012) |
| CH (1) | CH585206A5 (en, 2012) |
| DE (1) | DE2428201A1 (en, 2012) |
| DK (1) | DK137182B (en, 2012) |
| FR (1) | FR2233059B1 (en, 2012) |
| GB (1) | GB1462676A (en, 2012) |
| IE (1) | IE39977B1 (en, 2012) |
| IL (1) | IL44912A (en, 2012) |
| LU (1) | LU70286A1 (en, 2012) |
| NL (1) | NL7407827A (en, 2012) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0094065A3 (en) * | 1982-05-06 | 1984-08-22 | Ferrer Internacional, S.A. | 2-aminobenzoic acid derivatives, a process for their preparation and pharmaceutical compositions |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE448091B (sv) * | 1977-12-15 | 1987-01-19 | Roussel Uclaf | Nya 2-/(4-kinolinyl)-amino/-5-fluorbensoesyraderivat, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande dessa derivat |
| FR2434808A1 (fr) * | 1978-09-01 | 1980-03-28 | Science Union & Cie | Nouveaux esters du methyl-1 piperidinol-4, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| ES512605A0 (es) * | 1982-05-06 | 1983-02-16 | Ferrer Int | "procedimiento de obtencion de nuevos derivados del acido 2-aminobenzoico". |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2940974A (en) * | 1957-06-19 | 1960-06-14 | Sterling Drug Inc | 1-substituted-4-[(tertiary-or secondary-amino)-alkylimino]-1, 4-dihydroquinolines |
| US3174972A (en) * | 1961-07-10 | 1965-03-23 | Table ii | |
| CH408915A (fr) * | 1962-02-16 | 1966-03-15 | Roussel Uclaf | Procédé de préparation d'un nouveau composé utilisable, notamment, pour le traitement des manifestations inflammatoires et/ou douloureuses |
| FR7870M (en, 2012) * | 1968-11-08 | 1970-04-27 | ||
| BE785973A (fr) * | 1971-07-09 | 1973-01-08 | Roussel Uclaf | Nouvelles 4-amino quinoleines et procede de preparation |
-
1973
- 1973-06-13 FR FR7321434A patent/FR2233059B1/fr not_active Expired
-
1974
- 1974-05-29 IL IL44912A patent/IL44912A/xx unknown
- 1974-05-31 US US05/474,885 patent/US3944555A/en not_active Expired - Lifetime
- 1974-06-10 DK DK308374AA patent/DK137182B/da unknown
- 1974-06-11 LU LU70286A patent/LU70286A1/xx unknown
- 1974-06-11 DE DE19742428201 patent/DE2428201A1/de not_active Ceased
- 1974-06-11 JP JP49065659A patent/JPS5032185A/ja active Pending
- 1974-06-11 BE BE145289A patent/BE816175A/xx unknown
- 1974-06-12 NL NL7407827A patent/NL7407827A/xx not_active Application Discontinuation
- 1974-06-12 CH CH804974A patent/CH585206A5/xx not_active IP Right Cessation
- 1974-06-12 CA CA202,236A patent/CA1045140A/en not_active Expired
- 1974-06-13 GB GB2629474A patent/GB1462676A/en not_active Expired
- 1974-06-13 IE IE1245/74A patent/IE39977B1/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0094065A3 (en) * | 1982-05-06 | 1984-08-22 | Ferrer Internacional, S.A. | 2-aminobenzoic acid derivatives, a process for their preparation and pharmaceutical compositions |
| US4767767A (en) * | 1982-05-06 | 1988-08-30 | Ferrer Internacional S.A. | 2-pyrrolidinylethyl-2-(7-trifluoromethyl-4-quinolyl-aminobenzoate having analgesic, antipyretic and anti-inflammatory activities |
Also Published As
| Publication number | Publication date |
|---|---|
| US3944555A (en) | 1976-03-16 |
| FR2233059B1 (en, 2012) | 1976-09-03 |
| FR2233059A1 (en, 2012) | 1975-01-10 |
| DE2428201A1 (de) | 1975-01-09 |
| DK137182B (da) | 1978-01-30 |
| IL44912A0 (en) | 1974-07-31 |
| BE816175A (fr) | 1974-12-11 |
| JPS5032185A (en, 2012) | 1975-03-28 |
| NL7407827A (en, 2012) | 1974-12-17 |
| IE39977B1 (en) | 1979-02-14 |
| LU70286A1 (en, 2012) | 1975-03-06 |
| CA1045140A (en) | 1978-12-26 |
| DK137182C (en, 2012) | 1978-07-03 |
| IL44912A (en) | 1978-12-17 |
| CH585206A5 (en, 2012) | 1977-02-28 |
| IE39977L (en) | 1974-12-13 |
| DK308374A (en, 2012) | 1975-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |