GB1457619A - 2,6-dioxo-tetra and hexahydropyridine derivatives apparatuses for transferring threads from spinning and finishing parts of machines for continuous production of artificial threads to take-up and winding arrangements thereof - Google Patents

2,6-dioxo-tetra and hexahydropyridine derivatives apparatuses for transferring threads from spinning and finishing parts of machines for continuous production of artificial threads to take-up and winding arrangements thereof

Info

Publication number
GB1457619A
GB1457619A GB2781974A GB2781974A GB1457619A GB 1457619 A GB1457619 A GB 1457619A GB 2781974 A GB2781974 A GB 2781974A GB 2781974 A GB2781974 A GB 2781974A GB 1457619 A GB1457619 A GB 1457619A
Authority
GB
United Kingdom
Prior art keywords
methyl
dioxo
threads
alkyl
tetra
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2781974A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspro Nicholas Ltd
Original Assignee
Aspro Nicholas Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aspro Nicholas Ltd filed Critical Aspro Nicholas Ltd
Priority to GB2781974A priority Critical patent/GB1457619A/en
Priority to IE1347/75A priority patent/IE41708B1/en
Priority to ZA3902A priority patent/ZA753902B/en
Priority to AU82227/75A priority patent/AU8222775A/en
Priority to DK277275A priority patent/DK277275A/en
Priority to NL7507421A priority patent/NL7507421A/en
Priority to BE157524A priority patent/BE830462A/en
Priority to DE19752527581 priority patent/DE2527581A1/en
Priority to FR7519511A priority patent/FR2275201A1/en
Priority to JP50077445A priority patent/JPS51136675A/en
Publication of GB1457619A publication Critical patent/GB1457619A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1457619 2,6 - Dioxo - tetra- and hexahydropyridines ASPRO-NICHOLAS Ltd 23 June 1975 [22 June 1974] 27819/74 Heading C2C The invention comprises the title compounds, and their acid addition salts and quaternary ammonium derivatives, which contain (a) possibly a 1-alkyl substituent, (b) 3- (optionally substituted) Ph and 3-heterocyclyl- C 1-5 -alkyl substituents, as well as (c) 4- and/or 5-attached C 1-4 alkyl or C 3-8 (inclusive of the attached ring carbon atom or atoms) alkylene substituent, the "heterocyclyl" being derived from a non-aromatic N-containing 5-7 membered ring. The "alkyl" and "alkylene" radicals include unsaturated analogues. In an example, 1 - methyl - 2 - (2 - hydroxyethyl)pyridinium methosulphate is reduced to 1-methyl-2-(2- hydroxyethyl)piperidine which with SOCl 2 affords 1 - methyl - 2 - (2 - chloroethyl)piperidine, the latter condensed with m-methoxybenzyl cyanide to give 2 - (m - methoxyphenyl) - 4- (N - methyl - 2 - piperidyl)butyronitrile and then with 4 - (1 - ethoxy - 3 - methylbut - 2 - enylidene)morpholinium fluorosulphonate to give 2 - (1,1 - dimethyl - 2 - ethoxyethyl) - 2 - (mmethoxyphenyl) - 4 - (N - methyl - 2 - piperidyl)- butyronitrile, the latter being cyclized to 4,4-dimethyl - 2,6 - dioxo - 3 - m - methoxyphenyl- 3 - [2 - (N - methyl - 2 - piperidyl)ethyl]piperidine. Therapeutic compositions having C.N.S. activity comprise the title compounds, substituted as described above, and may be administered orally, parenterally or rectally.
GB2781974A 1974-06-22 1974-06-22 2,6-dioxo-tetra and hexahydropyridine derivatives apparatuses for transferring threads from spinning and finishing parts of machines for continuous production of artificial threads to take-up and winding arrangements thereof Expired GB1457619A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GB2781974A GB1457619A (en) 1974-06-22 1974-06-22 2,6-dioxo-tetra and hexahydropyridine derivatives apparatuses for transferring threads from spinning and finishing parts of machines for continuous production of artificial threads to take-up and winding arrangements thereof
IE1347/75A IE41708B1 (en) 1974-06-22 1975-06-16 2,6-dioxo-tetra and hexahydro-pyridine derivatives
ZA3902A ZA753902B (en) 1974-06-22 1975-06-18 Pyridine derivatives
AU82227/75A AU8222775A (en) 1974-06-22 1975-06-18 Glutarimide derivatives
DK277275A DK277275A (en) 1974-06-22 1975-06-19 PROCEDURE FOR PREPARING PYRIDINE DERIVATIVES
NL7507421A NL7507421A (en) 1974-06-22 1975-06-20 PROCESS FOR THE PREPARATION OF 3-PHENYL- -3- (HETEROCYCLICCHAMINE C1-C4-2,6-DIOXOTETRA AND HEXA-HYDROPYRIDINS, METHOD FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH ACTION ON THE CENTRAL NERVE, IN THE METHOD AN ANTI-DEPRESSION EMPLOYER AND SUCH MEDICINAL PRODUCT.
BE157524A BE830462A (en) 1974-06-22 1975-06-20 PYRIDINES 3-PHENYL-3- (HETEROCYCLIC AMINE) ALKYL-2,6-DIOXO- HYDORGENES, AND THEIR PREPARATION METHODS
DE19752527581 DE2527581A1 (en) 1974-06-22 1975-06-20 3-PHENYL-3- (HETEROCYCLIC AMINE) - ALKYL-2,6-DIOXO-HYDROPYRIDINE, THE PROCESS FOR THEIR MANUFACTURING AND THEIR USE IN PHARMACEUTICAL PREPARATIONS
FR7519511A FR2275201A1 (en) 1974-06-22 1975-06-23 PYRIDINES 3-PHENYL-3 (HETEROCYCLIC AMINE) ALKYL-2,6-DIOXOHYDROGENES, AND THEIR PREPARATION PROCEDURES
JP50077445A JPS51136675A (en) 1974-06-22 1975-06-23 Preparation method of 33phenyl 33*heterocyclicamin*alkyll2*66 dioxoohydrogenatedpyridines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2781974A GB1457619A (en) 1974-06-22 1974-06-22 2,6-dioxo-tetra and hexahydropyridine derivatives apparatuses for transferring threads from spinning and finishing parts of machines for continuous production of artificial threads to take-up and winding arrangements thereof

Publications (1)

Publication Number Publication Date
GB1457619A true GB1457619A (en) 1976-12-08

Family

ID=10265816

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2781974A Expired GB1457619A (en) 1974-06-22 1974-06-22 2,6-dioxo-tetra and hexahydropyridine derivatives apparatuses for transferring threads from spinning and finishing parts of machines for continuous production of artificial threads to take-up and winding arrangements thereof

Country Status (10)

Country Link
JP (1) JPS51136675A (en)
AU (1) AU8222775A (en)
BE (1) BE830462A (en)
DE (1) DE2527581A1 (en)
DK (1) DK277275A (en)
FR (1) FR2275201A1 (en)
GB (1) GB1457619A (en)
IE (1) IE41708B1 (en)
NL (1) NL7507421A (en)
ZA (1) ZA753902B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011234A1 (en) * 1993-10-22 1995-04-27 Australian Nuclear Science & Technology Organisation Radiolabelled ligands for muscarinic receptors

Also Published As

Publication number Publication date
AU8222775A (en) 1976-12-23
DK277275A (en) 1975-12-23
BE830462A (en) 1975-12-22
FR2275201A1 (en) 1976-01-16
NL7507421A (en) 1975-12-24
JPS51136675A (en) 1976-11-26
DE2527581A1 (en) 1976-01-08
IE41708L (en) 1975-12-22
IE41708B1 (en) 1980-03-12
ZA753902B (en) 1977-01-26

Similar Documents

Publication Publication Date Title
EP0176927A3 (en) Diazepine-containing pharmaceutical compositions having a platelet activating factor (paf)-antagonist action
ZA925682B (en) New benzimidazolone derivatives
KR930002364A (en) Trifluoro Methylbenzyl Phosphonate Useful to Treat Osteoporosis
ES2083464T3 (en) HETERO CYCLIC COMPOUNDS.
ES465047A1 (en) N-Benzhydryloxyethyl-N-phenylpropyl-piperazines
DE68914292D1 (en) Composition for the treatment of ischemic disorders in organs.
DE69115297D1 (en) LEUKOTRIA B4 ANTAGONISTS.
GB1034939A (en) Isoxazole derivative and processes for its production
DK26289D0 (en) USE OF 1,4-DISUBSTITUTED PIPERIDINYL FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION FOR TREATING INSOMNIA
ATE59632T1 (en) DIHYDRODIBENZOCYCLOHEPTYLIDENETHYLAMINE DERIVATIVES
GB1457619A (en) 2,6-dioxo-tetra and hexahydropyridine derivatives apparatuses for transferring threads from spinning and finishing parts of machines for continuous production of artificial threads to take-up and winding arrangements thereof
FR2677020B1 (en) COMPOUNDS DERIVED FROM BENZIMIDAZOLE, THEIR PREPARATION PROCESS AND THEIR USE IN THE THERAPEUTIC AND COSMETIC FIELDS.
ES8203354A1 (en) 1,2,4-Triazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing them.
GB1426028A (en) 2-oxazoline derivatives
ES8504159A1 (en) Esters of 3-(3-substituted-amino-2-hydroxypropoxy)-4-substituted-1,2,5-thiadiazole derivatives.
ES8400099A1 (en) Diazolyl alkanoles, process for their preparation and their use as antimycotic agents.
DE3363740D1 (en) 3-pyridyl-5-alkoxy-(or phenoxy- or aralkyloxy-)pyrazole derivatives, process for their preparation, and their therapeutical use
GB822777A (en) Improvements in or relating to halophenothiazine derivatives
ES514634A0 (en) "A PROCEDURE FOR THE PREPARATION OF 2- (1,4-BENZODIOXAN-2-IL-METHYL) -IMIDAZOLINE".
NO871140L (en) PROCEDURE FOR THE PREPARATION OF NEW 1- (3- (2- (4-MORPHOLINYL) -ETOXY) - (2-DIALKYLAMINETOXYX) -2-TIENYL) -3-PHENYL-PROPANONES AND ACID ADDITION SALTS THEREOF.
GB1042299A (en) Quinazoline derivatives
FR2185717A1 (en) Low viscosity plasticisers - using quat ammonium salts as viscosity depressant
ES8301933A1 (en) 4-(5)-alkylmercaptoimidazole derivatives, a process for their production and medicaments containing these compounds
GB1056044A (en) 5,10-disubstituted dibenzodiazepinones
KR920006353A (en) Substituted 3-aminosidone imine, preparation method thereof and use thereof

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee