GB1457439A - 11-oxygenated pregneno-17,16a-d-1,3,-oxathiolans - Google Patents
11-oxygenated pregneno-17,16a-d-1,3,-oxathiolansInfo
- Publication number
- GB1457439A GB1457439A GB5877373A GB5877373A GB1457439A GB 1457439 A GB1457439 A GB 1457439A GB 5877373 A GB5877373 A GB 5877373A GB 5877373 A GB5877373 A GB 5877373A GB 1457439 A GB1457439 A GB 1457439A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dione
- fluoro
- pregnadiene
- hydroxy
- dihydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000004593 Epoxy Substances 0.000 abstract 4
- 150000003431 steroids Chemical class 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Natural products C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- RJKFOVLPORLFTN-UHFFFAOYSA-N progesterone acetate Natural products C1CC2=CC(=O)CCC2(C)C2C1C1CCC(C(=O)C)C1(C)CC2 RJKFOVLPORLFTN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
- C07J7/006—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a hydroxy group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0073—Sulfur-containing hetero ring
- C07J71/0089—Sulfur-containing hetero ring containing sulfur and oxygen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2264001A DE2264001C2 (de) | 1972-12-22 | 1972-12-22 | 11β-Hydroxy-2',2'-dimethyl-1,4-pregnadieno[17,16α-d]-1',3'-oxathiolan-3,20-dion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1457439A true GB1457439A (en) | 1976-12-01 |
Family
ID=5865746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5877373A Expired GB1457439A (en) | 1972-12-22 | 1973-12-19 | 11-oxygenated pregneno-17,16a-d-1,3,-oxathiolans |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3894004A (enExample) |
| JP (1) | JPS4994659A (enExample) |
| BE (1) | BE808984A (enExample) |
| CH (1) | CH609066A5 (enExample) |
| DD (1) | DD108530A5 (enExample) |
| DE (1) | DE2264001C2 (enExample) |
| DK (1) | DK132123C (enExample) |
| FR (1) | FR2211258B1 (enExample) |
| GB (1) | GB1457439A (enExample) |
| NL (1) | NL7317655A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5792758A (en) * | 1995-12-08 | 1998-08-11 | G. D. Searle & Co. | Steroid nitrite ester derivatives useful as anti-inflammatory drugs |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3170920A (en) * | 1962-08-10 | 1965-02-23 | Shionogi & Co | 3-oxo-16beta-mercapto-17beta-hydroxy-5alpha-androstane-16-17 acetonides and the process for the production thereof |
| US3770726A (en) * | 1972-03-16 | 1973-11-06 | Schering Ag | Pregnano717,16alpha-d)-1',3'-oxathiolanes |
-
1972
- 1972-12-22 DE DE2264001A patent/DE2264001C2/de not_active Expired
-
1973
- 1973-12-10 CH CH1729773A patent/CH609066A5/xx not_active IP Right Cessation
- 1973-12-18 DK DK688673A patent/DK132123C/da active
- 1973-12-19 GB GB5877373A patent/GB1457439A/en not_active Expired
- 1973-12-20 DD DD175540A patent/DD108530A5/xx unknown
- 1973-12-20 US US426600A patent/US3894004A/en not_active Expired - Lifetime
- 1973-12-21 BE BE139170A patent/BE808984A/xx unknown
- 1973-12-21 JP JP49004709A patent/JPS4994659A/ja active Pending
- 1973-12-22 NL NL7317655A patent/NL7317655A/xx not_active Application Discontinuation
- 1973-12-26 FR FR7346232A patent/FR2211258B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK132123C (da) | 1976-03-29 |
| US3894004A (en) | 1975-07-08 |
| DE2264001C2 (de) | 1982-08-26 |
| JPS4994659A (enExample) | 1974-09-09 |
| FR2211258A1 (enExample) | 1974-07-19 |
| CH609066A5 (enExample) | 1979-02-15 |
| DE2264001A1 (de) | 1974-07-04 |
| DK132123B (da) | 1975-10-27 |
| NL7317655A (enExample) | 1974-06-25 |
| BE808984A (fr) | 1974-06-21 |
| FR2211258B1 (enExample) | 1976-09-03 |
| DD108530A5 (enExample) | 1974-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |