GB145621A - Process for obtaining the active ingredient of lobelia inflata - Google Patents

Process for obtaining the active ingredient of lobelia inflata

Info

Publication number
GB145621A
GB145621A GB1779520A GB1779520A GB145621A GB 145621 A GB145621 A GB 145621A GB 1779520 A GB1779520 A GB 1779520A GB 1779520 A GB1779520 A GB 1779520A GB 145621 A GB145621 A GB 145621A
Authority
GB
United Kingdom
Prior art keywords
lobeline
extracting
chloroform
obtaining
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1779520A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of GB145621A publication Critical patent/GB145621A/en
Expired legal-status Critical Current

Links

Landscapes

  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Three alkaloids, termed a -, b -, and g -lobeline, are isolated from the crude alkaloid of lobelia inflata by dissolving the crude product in hydrochloric acid, crystallizing out the difficulty-soluble hydrochloride of b -lobeline, and extracting the hydrochloride of a -lobeline, from the mother-liquor by means of chloroform. The chloroform solution is mixed with soda solution, the chloroform evaporated off, and the a -lobeline crystallized out; it is formulated as C21H23O2N. The b - and g -lobeline are not crystalline. The crude alkaloid employed may be obtained by extracting the drug by alcohol, distilling off the alcohol, dissolving the bases in dilute acid, neutralizing the acid solutions by alkali and extracting with ether; or the first extract may be made with ether or benzene.
GB1779520A 1914-04-04 1920-06-29 Process for obtaining the active ingredient of lobelia inflata Expired GB145621A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE93814X 1914-04-04

Publications (1)

Publication Number Publication Date
GB145621A true GB145621A (en) 1921-01-20

Family

ID=5644807

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1779520A Expired GB145621A (en) 1914-04-04 1920-06-29 Process for obtaining the active ingredient of lobelia inflata

Country Status (2)

Country Link
CH (1) CH93814A (en)
GB (1) GB145621A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541105A (en) * 1967-06-29 1970-11-17 Esteban Nunez Melendez Process for obtaining the principal alkaloid of the plant tup a portoricensis vatke

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541105A (en) * 1967-06-29 1970-11-17 Esteban Nunez Melendez Process for obtaining the principal alkaloid of the plant tup a portoricensis vatke

Also Published As

Publication number Publication date
CH93814A (en) 1922-03-16

Similar Documents

Publication Publication Date Title
HU194209B (en) Process for preparing novel pyridine-2-ether derivatives and pyridine-2-thioether derivative having nitrogen-containing cycloaliphatic ring and pharmaceuticals comprising the same
JPS6152155B2 (en)
US3318926A (en) 7alpha-methyl-16alpha-hydroxy-estrones
GB145621A (en) Process for obtaining the active ingredient of lobelia inflata
DE1770062B2 (en) Tetrahydroisoquinolylpenicillins, processes for their preparation and pharmaceutical compositions
US2203121A (en) Preparation of diacetyldihydromorphinone
US3324111A (en) Speciofoline, an alkaloid from mitragyna speciosa
US3000896A (en) Process for the manufacture of second-
Forsyth et al. CCXX.—iso Quinoline derivatives. Part IX. Preparation and reduction of iso quinoline and its derivatives
Deulofeu et al. Studies on argentine plants. VIII. The alkaloids of erythrina crista galli. Chromatographic separation of erythratine and erysodine
Smith CCLXX.—l-Methylephedrine, an alkaloid from Ephedra species
JPS6225149B2 (en)
JP2017537125A (en) Compositions and methods for treating diseases and conditions
US2235661A (en) Hydrohaodes of pseudotropine
US2114306A (en) Improved method of separating
Begtrup et al. Studies on Methylated 1, 2, 3-Triazoles. II
US3072664A (en) Extraction of raunitidine
US2086562A (en) Method of sepaeating mixed ergot
US2391015A (en) Alkaloid and processes for producing the same
US3457258A (en) 5h-1,4-benzodiazepin-5-ones and-5-thiones
Tomita et al. Studies on the Alkaloids of Magnoliaceous Plants. VIII Alkaloids of Magnolia denudata Desr.(1)
US3517061A (en) 5h-1,4-benzodiazepin-5-ones
US2412256A (en) Process for the production of erythrina alkaloids
US2938906A (en) Certificate of correction
WENKERT et al. The stereochemistry of tetrahydroalstonine and related indole alkaloids