GB1455888A - Dihydropyridines - Google Patents
DihydropyridinesInfo
- Publication number
- GB1455888A GB1455888A GB3495874A GB3495874A GB1455888A GB 1455888 A GB1455888 A GB 1455888A GB 3495874 A GB3495874 A GB 3495874A GB 3495874 A GB3495874 A GB 3495874A GB 1455888 A GB1455888 A GB 1455888A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- radical
- phenyl
- dicyano
- alkali
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004925 dihydropyridyl group Chemical group N1(CC=CC=C1)* 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 N - Substituted 3,5 - dicyano - 1,4 - dihydropyridines Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- VCLSSIUDTNSANT-UHFFFAOYSA-N 1,4-dihydropyridine-3,5-dicarbonitrile Chemical compound N#CC1=CNC=C(C#N)C1 VCLSSIUDTNSANT-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229910000102 alkali metal hydride Inorganic materials 0.000 abstract 1
- 150000008046 alkali metal hydrides Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229940085304 dihydropyridine derivative selective calcium channel blockers with mainly vascular effects Drugs 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 239000003880 polar aprotic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS6416A CS168272B1 (enExample) | 1973-09-18 | 1973-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1455888A true GB1455888A (en) | 1976-11-17 |
Family
ID=5411137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3495874A Expired GB1455888A (en) | 1973-09-18 | 1974-08-08 | Dihydropyridines |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3969359A (enExample) |
| JP (1) | JPS5076075A (enExample) |
| CH (1) | CH602647A5 (enExample) |
| CS (1) | CS168272B1 (enExample) |
| DE (1) | DE2444654A1 (enExample) |
| FR (1) | FR2243942B3 (enExample) |
| GB (1) | GB1455888A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0330470A3 (en) * | 1988-02-24 | 1992-01-02 | Ajinomoto Co., Inc. | 1,4-dihydropyridine derivatives useful against tumour cells |
| US5216172A (en) * | 1988-02-24 | 1993-06-01 | Ajinomoto Co., Inc. | 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells |
| ES2396160T3 (es) * | 2006-12-14 | 2013-02-19 | Bayer Intellectual Property Gmbh | Derivados de DIHIDROPIRIDINA que utiliza como inhibidores de la proteina quinasa |
-
1973
- 1973-09-18 CS CS6416A patent/CS168272B1/cs unknown
-
1974
- 1974-08-08 GB GB3495874A patent/GB1455888A/en not_active Expired
- 1974-08-30 CH CH1185574A patent/CH602647A5/xx not_active IP Right Cessation
- 1974-09-11 US US05/505,006 patent/US3969359A/en not_active Expired - Lifetime
- 1974-09-17 JP JP49106136A patent/JPS5076075A/ja active Pending
- 1974-09-18 FR FR7431572A patent/FR2243942B3/fr not_active Expired
- 1974-09-18 DE DE19742444654 patent/DE2444654A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CS168272B1 (enExample) | 1976-05-28 |
| FR2243942B3 (enExample) | 1977-07-01 |
| CH602647A5 (enExample) | 1978-07-31 |
| DE2444654A1 (de) | 1975-03-27 |
| JPS5076075A (enExample) | 1975-06-21 |
| FR2243942A1 (enExample) | 1975-04-11 |
| US3969359A (en) | 1976-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |