GB1449364A - Pyrrolo 3-4-b- pyridines and method for their preparation - Google Patents
Pyrrolo 3-4-b- pyridines and method for their preparationInfo
- Publication number
- GB1449364A GB1449364A GB1238674A GB1238674A GB1449364A GB 1449364 A GB1449364 A GB 1449364A GB 1238674 A GB1238674 A GB 1238674A GB 1238674 A GB1238674 A GB 1238674A GB 1449364 A GB1449364 A GB 1449364A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- substituted
- formula
- compounds
- pyridines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- VSUQKXYKYUOJAP-UHFFFAOYSA-N 1-phenyl-N-(1H-pyrrol-3-yl)methanimine Chemical class C(C1=CC=CC=C1)=NC1=CNC=C1 VSUQKXYKYUOJAP-UHFFFAOYSA-N 0.000 abstract 1
- -1 1-substituted-3-benzalaminopyrroles Chemical class 0.000 abstract 1
- WAUGGYPDCQZJKK-UHFFFAOYSA-N 1h-pyrrol-3-amine Chemical class NC=1C=CNC=1 WAUGGYPDCQZJKK-UHFFFAOYSA-N 0.000 abstract 1
- QJMCIPBZDVYHDC-UHFFFAOYSA-N N1C=CC=C2C=NC=C21 Chemical class N1C=CC=C2C=NC=C21 QJMCIPBZDVYHDC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000003431 anti-prostaglandin Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1238674A GB1449364A (en) | 1974-03-20 | 1974-03-20 | Pyrrolo 3-4-b- pyridines and method for their preparation |
| US05/559,092 US3983127A (en) | 1974-03-20 | 1975-03-17 | Pyrrolo[3,4-b]pyridines |
| DE19752511585 DE2511585A1 (de) | 1974-03-20 | 1975-03-17 | Pyrrolo eckige klammer auf 3,4-b eckige klammer zu pyridine, verfahren zu ihrer herstellung und arzneimittel |
| DK111575AA DK141288B (da) | 1974-03-20 | 1975-03-19 | Analogifremgangsmåde til fremstilling af pyrrol(3,4-b)pyridiner eller syreadditionssalte deraf. |
| CA75222572A CA1049017A (en) | 1974-03-20 | 1975-03-19 | Pyrrolo (3,4-b) pyridines and methods for their preparation |
| NL7503254A NL7503254A (nl) | 1974-03-20 | 1975-03-19 | Pyrrolo (3,4-b)pyridinen en werkwijze voor de bereiding daarvan. |
| JP3420375A JPS5637993B2 (en:Method) | 1974-03-20 | 1975-03-20 | |
| BE154539A BE826926A (fr) | 1974-03-20 | 1975-03-20 | Pyrrolo (3,4-b) pyridines et leur preparation |
| FR7508668A FR2264534B1 (en:Method) | 1974-03-20 | 1975-03-20 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1238674A GB1449364A (en) | 1974-03-20 | 1974-03-20 | Pyrrolo 3-4-b- pyridines and method for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1449364A true GB1449364A (en) | 1976-09-15 |
Family
ID=10003604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1238674A Expired GB1449364A (en) | 1974-03-20 | 1974-03-20 | Pyrrolo 3-4-b- pyridines and method for their preparation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3983127A (en:Method) |
| JP (1) | JPS5637993B2 (en:Method) |
| BE (1) | BE826926A (en:Method) |
| CA (1) | CA1049017A (en:Method) |
| DE (1) | DE2511585A1 (en:Method) |
| DK (1) | DK141288B (en:Method) |
| FR (1) | FR2264534B1 (en:Method) |
| GB (1) | GB1449364A (en:Method) |
| NL (1) | NL7503254A (en:Method) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4227747A1 (de) * | 1992-08-21 | 1994-02-24 | Basf Ag | Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung |
| KR101099849B1 (ko) * | 2003-11-19 | 2011-12-28 | 어레이 바이오파마 인크. | Mek의 헤테로시클릭 억제제 및 그의 사용 방법 |
-
1974
- 1974-03-20 GB GB1238674A patent/GB1449364A/en not_active Expired
-
1975
- 1975-03-17 US US05/559,092 patent/US3983127A/en not_active Expired - Lifetime
- 1975-03-17 DE DE19752511585 patent/DE2511585A1/de not_active Withdrawn
- 1975-03-19 NL NL7503254A patent/NL7503254A/xx not_active Application Discontinuation
- 1975-03-19 DK DK111575AA patent/DK141288B/da unknown
- 1975-03-19 CA CA75222572A patent/CA1049017A/en not_active Expired
- 1975-03-20 FR FR7508668A patent/FR2264534B1/fr not_active Expired
- 1975-03-20 JP JP3420375A patent/JPS5637993B2/ja not_active Expired
- 1975-03-20 BE BE154539A patent/BE826926A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2264534B1 (en:Method) | 1978-08-04 |
| US3983127A (en) | 1976-09-28 |
| DK111575A (en:Method) | 1975-09-21 |
| BE826926A (fr) | 1975-07-16 |
| DK141288C (en:Method) | 1980-08-11 |
| DK141288B (da) | 1980-02-18 |
| JPS5637993B2 (en:Method) | 1981-09-03 |
| CA1049017A (en) | 1979-02-20 |
| NL7503254A (nl) | 1975-09-23 |
| JPS50135097A (en:Method) | 1975-10-25 |
| FR2264534A1 (en:Method) | 1975-10-17 |
| DE2511585A1 (de) | 1975-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |