GB1445707A - Imidazolyl-indane and imidazolyl-tetralin derivatives - Google Patents
Imidazolyl-indane and imidazolyl-tetralin derivativesInfo
- Publication number
- GB1445707A GB1445707A GB3928873A GB3928873A GB1445707A GB 1445707 A GB1445707 A GB 1445707A GB 3928873 A GB3928873 A GB 3928873A GB 3928873 A GB3928873 A GB 3928873A GB 1445707 A GB1445707 A GB 1445707A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compounds
- reacting
- imidazolyl
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FSOUVFKZLYLZCE-UHFFFAOYSA-N 2-(2,3-dihydro-1h-inden-1-yl)-1h-imidazole Chemical compound C1CC2=CC=CC=C2C1C1=NC=CN1 FSOUVFKZLYLZCE-UHFFFAOYSA-N 0.000 title abstract 2
- BLXFHJKHZWXNDP-UHFFFAOYSA-N 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-1h-imidazole Chemical class C12=CC=CC=C2CCCC1C1=NC=CN1 BLXFHJKHZWXNDP-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- MOIPGXQKZSZOQX-UHFFFAOYSA-N carbonyl bromide Chemical compound BrC(Br)=O MOIPGXQKZSZOQX-UHFFFAOYSA-N 0.000 abstract 2
- 239000003638 chemical reducing agent Substances 0.000 abstract 2
- GKIPXFAANLTWBM-UHFFFAOYSA-N epibromohydrin Chemical compound BrCC1CO1 GKIPXFAANLTWBM-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- QNXSIUBBGPHDDE-UHFFFAOYSA-N indan-1-one Chemical compound C1=CC=C2C(=O)CCC2=C1 QNXSIUBBGPHDDE-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XHLHPRDBBAGVEG-UHFFFAOYSA-N 1-tetralone Chemical compound C1=CC=C2C(=O)CCCC2=C1 XHLHPRDBBAGVEG-UHFFFAOYSA-N 0.000 abstract 1
- 241001480043 Arthrodermataceae Species 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910004013 NO 2 Inorganic materials 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000037304 dermatophytes Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722244761 DE2244761A1 (de) | 1972-09-09 | 1972-09-09 | Indan- und tetralinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1445707A true GB1445707A (en) | 1976-08-11 |
Family
ID=5856137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3928873A Expired GB1445707A (en) | 1972-09-09 | 1973-08-20 | Imidazolyl-indane and imidazolyl-tetralin derivatives |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4962467A (enrdf_load_stackoverflow) |
| AT (1) | AT323737B (enrdf_load_stackoverflow) |
| BE (1) | BE804599A (enrdf_load_stackoverflow) |
| DD (1) | DD107459A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2244761A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2198752B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1445707A (enrdf_load_stackoverflow) |
| HU (1) | HU165751B (enrdf_load_stackoverflow) |
| NL (1) | NL7312417A (enrdf_load_stackoverflow) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0054233A1 (en) * | 1980-12-12 | 1982-06-23 | Schering Corporation | Novel benzo(b)thiophenes, benzo(b)furans, thiochromans and chromans, processes for their preparation and antimicrobial compositions containing them |
| US4431816A (en) * | 1980-12-12 | 1984-02-14 | Schering Corporation | 2,3-Dihydro-2-(imidazolylmethyl)benzo(b)thiophenes |
| US4468404A (en) * | 1980-12-12 | 1984-08-28 | Schering Corporation | 3-Aralkyloxy-2,3-dihydro-2-(triazolymethyl)benzo(b)thiophenes |
| US4492707A (en) * | 1981-07-23 | 1985-01-08 | Farmitalia Carlo Erba S.P.A. | N-Imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan |
| US5091539A (en) * | 1984-02-03 | 1992-02-25 | Shionogi & Co., Ltd. | Azolyl cycloalkanol derivatives and agricultural fungicides |
| US5204364A (en) * | 1988-10-06 | 1993-04-20 | Farmitalia Carlo Erba, S.R.L. | N-imidazolyl- and n-imidazolylmethyl-derivatives of substituted bicyclic compounds |
| US6956129B2 (en) | 2001-02-16 | 2005-10-18 | Bayer Aktiengesellschaft | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3369131D1 (en) * | 1982-04-22 | 1987-02-19 | Ici Plc | Antifungal azolyl phenyl substituted alicyclic alcohols |
| TW318184B (enrdf_load_stackoverflow) * | 1991-11-30 | 1997-10-21 | Hoechst Ag | |
| EP2368876A1 (en) * | 2010-03-01 | 2011-09-28 | Sanofi | Derivatives of aminoindanes, their preparation and their application in therapeutics |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3636002A (en) * | 1969-12-15 | 1972-01-18 | Janssen Pharmaceutica Nv | 1-(2-halobenzyloxy-1-indanyl)-imidazoles |
-
1972
- 1972-09-09 DE DE19722244761 patent/DE2244761A1/de active Pending
-
1973
- 1973-08-20 GB GB3928873A patent/GB1445707A/en not_active Expired
- 1973-09-05 AT AT770673A patent/AT323737B/de not_active IP Right Cessation
- 1973-09-07 FR FR7332334A patent/FR2198752B1/fr not_active Expired
- 1973-09-07 BE BE135437A patent/BE804599A/xx unknown
- 1973-09-07 HU HUSE000443 patent/HU165751B/hu unknown
- 1973-09-07 NL NL7312417A patent/NL7312417A/xx unknown
- 1973-09-07 DD DD17335873A patent/DD107459A5/xx unknown
- 1973-09-10 JP JP48102008A patent/JPS4962467A/ja active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0054233A1 (en) * | 1980-12-12 | 1982-06-23 | Schering Corporation | Novel benzo(b)thiophenes, benzo(b)furans, thiochromans and chromans, processes for their preparation and antimicrobial compositions containing them |
| US4352808A (en) * | 1980-12-12 | 1982-10-05 | Schering Corporation | 3-Aralkyloxy-2,3-dihydro-2-(imidazolylmethyl)benzo(b)thiophenes and related derivatives, their use as antimicrobials and pharmaceutical formulations useful therefore |
| US4431816A (en) * | 1980-12-12 | 1984-02-14 | Schering Corporation | 2,3-Dihydro-2-(imidazolylmethyl)benzo(b)thiophenes |
| US4468404A (en) * | 1980-12-12 | 1984-08-28 | Schering Corporation | 3-Aralkyloxy-2,3-dihydro-2-(triazolymethyl)benzo(b)thiophenes |
| US4492707A (en) * | 1981-07-23 | 1985-01-08 | Farmitalia Carlo Erba S.P.A. | N-Imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan |
| US5091539A (en) * | 1984-02-03 | 1992-02-25 | Shionogi & Co., Ltd. | Azolyl cycloalkanol derivatives and agricultural fungicides |
| US5204364A (en) * | 1988-10-06 | 1993-04-20 | Farmitalia Carlo Erba, S.R.L. | N-imidazolyl- and n-imidazolylmethyl-derivatives of substituted bicyclic compounds |
| US6956129B2 (en) | 2001-02-16 | 2005-10-18 | Bayer Aktiengesellschaft | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives |
| US7381832B2 (en) | 2001-02-16 | 2008-06-03 | Lanxess Deutschland Gmbh | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| DD107459A5 (enrdf_load_stackoverflow) | 1974-08-05 |
| HU165751B (enrdf_load_stackoverflow) | 1974-10-28 |
| FR2198752A1 (enrdf_load_stackoverflow) | 1974-04-05 |
| FR2198752B1 (enrdf_load_stackoverflow) | 1976-09-03 |
| DE2244761A1 (de) | 1974-03-14 |
| BE804599A (fr) | 1974-03-07 |
| JPS4962467A (enrdf_load_stackoverflow) | 1974-06-17 |
| NL7312417A (enrdf_load_stackoverflow) | 1974-03-12 |
| ATA770674A (de) | 1975-01-15 |
| AT323737B (de) | 1975-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |